Kcal vs. protein (was: [Re: Which calories?])

[Guest guest]

Hi Willie:

From the same authors:

" In the group of mice with 60% intake of a carbohydrate-free (i.e.,

high fat) diet, mean longevity was doubled as compared to that of ad

libitum-fed mice. However, when the nonprotein energy was supplied by

carbohydrate (sucrose and glycerol) the mean longevity was three

times that of the ad libitum-fed groups ...................

clearly, although energy intake restriction provides significant

influence on longevity, very high fat diets do not give the same

protection as do high carbohydrate diets. " PMID: 3598724.

And,

" .......... In mice consuming a restricted energy intake of a diet

providing identical amounts of protein to those consumed by ad

libitum-fed mice, whether the protein intake was very high or normal,

longevity was equally greatly prolonged. " PMID: 3598725.

Based on this one would be tempted to conclude, as Pritikin did a

long time ago, that it is FAT restriction that is critical. But

these are old studies and, as Willie noted, these are a very specific

type of mice. So who knows if the results will be found apply to

humans. But they do seem to agree with Mair, Partridge & Co that

carbohydrate is not the really key component, in mice as well as

fruit flies. And these results suggest that Mair and Partridge may

right now be in the midst of discovering that fat is much more

important than protein or carbs. We will see. But either way it

will have interesting ramifications.

Rodney.

--- In , " Rodney " <perspect1111@y...>

wrote:

> Hi Willie:

>

> This part is interesting:

>

> " ......... but the calorie restriction did not produce as much

life

> extension when the diets had a high fat or high protein content as

it

> did when the diet had a very high proportion of carbohydrates "

>

> because it seems to be consistent with the fruit fly study where

> restriction of carbohydrates didn't make much difference.

>

> But is it the fat or the protein that matters?

>

> Rodney.

>

> --- In , " " <wmbragg@h...>

wrote:

> > Hi all,

> >

> > Here you have a reference that points just in another direction

> > regarding the issue of calories from carbs or protein. Of course,

> > one have to have in mind this strain of mice had a renal disease,

> > but it's worth reading it

> >

> > http://www.pnas.org/cgi/reprint/83/15/5659

> >

> > Take a look at this extract:

> >

> > " It was also of interest that the diet that promoted the very

> > longest life and the greatest increase in maximum life span in

> > these relatively short-lived mice was the diet of very high

> > carbohydrate, low fat, normal protein composition. However,

> > this diet exhibited the greatly beneficial effect only when

> > fed as a calorie-restricted diet. The diets higher in fat and

> > higher in protein permitted the increasing of longevity and life

> > span when fed in restricted amounts, but the calorie restriction

> > did not produce as much life extension when the diets

> > had a high fat or high protein content as it did when the diet

> > had a very high proportion of carbohydrates. "

> >

> > Cheers.

> > Willie.