Vinegar diet effect

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Hi All,

See the not pdf-available paper that dietary acetic acid is good. Have a blood

lower ratio of insulin to glucagon seems to be beneficial. Increasing liver

glycogen levels and fatty acid oxidation seems to be other pluses.

Effect of acetic acid feeding on the circadian changes in glycogen and

metabolites of glucose and lipid in liver and skeletal muscle of rats

Fushimi, Takashi; Sato, Yuzo

British Journal of Nutrition, Volume 94, Number 5, November 2005, pp. 714-719

Abstract:

The aim of the present study is to investigate the effect of acetic acid feeding

on

the circadian changes in glycogen concentration in liver and skeletal muscle.

Rats

were provided meal once daily (09.00–13.00 hours) for 10 & #8201;d. On the 11th

day,

they were either killed immediately or given 9 & #8201;g diet containing either 0

(control) or 0·7 & #8201;g/kg-diet acetic acid beginning at 09.00 hours for

4 & #8201;h,

as in the previous regimen. Rats in the fed group were killed at 4, 8 or

24 & #8201;h

after the start of feeding. At 4 & #8201;h after the start of feeding, the acetic

acid

group had significantly greater liver and gastrocnemius muscle glycogen

concentrations (P<0·05). Also, at this same point, liver xylulose-5-phosphate, a

key

stimulator of glycolysis, the ratio of fructose-1,6-bisphosphate to

fructose-6-phosphate in skeletal muscle, which reflects phosphofructokinase-1

activity, and liver malonyl-CoA, an allosteric inhibitor of carnitine

palmitoyl-transferase, were significantly lower in the acetic acid group than in

the

control group (P<0·05). In addition, the acetic acid group had a significantly

lower

serum lactate concentration and lower ratio of insulin to glucagon than the

control

group at the same point (P<0·05). We conclude that a diet containing acetic acid

may

enhance glycogen repletion but not induce supercompensation, a large increase in

the

glycogen level that is beneficial in improving performance, in liver and

skeletal

muscle by transitory inhibition of glycolysis. Further, we indicate the

possibility

of a transient enhancement of fatty acid oxidation in liver by acetic acid

feeding.

Al Pater, PhD; email: old542000@...

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