It's the FIBER ...

[Guest guest]

Hmm.. it's the fiber?

Can J Physiol Pharmacol. 2003 Nov;81(11):1042-8.

Dietary restriction and fibre supplementation: oxidative stress

and metabolic shifting for cardiac health.

Diniz YS, Cicogna AC, Padovani CR, Silva MD, Faine LA, Galhardi

CM, Rodrigues HG, Novelli EL.

Faculty of Medicine, UNESP, Botucatu, Sao o, Brazil.

Dietary modification ought to be the first line of strategy in

prevention of the development of cardiac disease. The purpose of this

study was to investigate whether dietary restriction,

dietary-fibre-enriched diet, and their interactions might affect

antioxidant capacity and oxidative stress in cardiac tissue. Male

Wistar rats (180-200 g; n=10) were divided into four groups: control

ad libitum diet ©, 50% restricted diet (DR), fed with fibre-enriched

diet (F), and 50% restricted fibre-enriched diet (DR-F). After 35 days

of the treatments, F, DR, and DR-F rats showed low cholesterol,

LDL-cholesterol, and triacylglycerol, and high HDL-cholesterol in

serum. The DR, DR-F, and F groups had decreased myocardial

lipoperoxide and lipid hydroperoxide. The DR-F and F treatments

increased superoxide dismutase and glutatione peroxidase (GSH-Px). The

DR treatment increased GSH-Px and catalase activities. Dietary fibre

beneficial effects were related to metabolic alterations. The F and

DR-F groups showed high cardiac glycogen and low lactate

dehydrogenase/citrate synthase ratios, indicating diminished anaerobic

and elevated aerobic myocardial metabolism in these animals. There was

no synergistic effect between dietary restriction and dietary fibre

addition, since no differences were observed in markers of oxidative

stress in the F and DR-F groups. Dietary fibre supplementation, rather

than energy intake and dietary restriction, appears to be the main

process retarding oxidative stress in cardiac tissue.

PMID: 14719039