Pre- and during-CR +/- grazing

[Guest guest]

Hi All,

The effectiveness of CR with different meal patterns before and during CR, may

be

the subject of the not pdf-available below paper. Grazing versus 3-meals/day

patterns seem to be equal in their effectiveness for the benefits of CR as well

as

the effectiveness.

That the dieters lost weight is taken to be a guage of the effect of the advice

they

wer given to restrict calories being effectuated.

Poston WS, Haddock CK, Pinkston MM, Pace P, Karakoc ND, Reeves RS, Foreyt JP.

Weight loss with meal replacement and meal replacement plus snacks: a randomized

trial.

Int J Obes Relat Metab Disord. 2005 Sep;29(9):1107-14.

PMID: 15925955

OBJECTIVE: To evaluate whether snacking would improve weight loss and weight

maintenance in overweight individuals within the context of a structured meal

replacement (MR) weight loss program. DESIGN: A prospective 24 week, 2 (snacking

vs

nonsnacking) x 2 (MR vs meal replacement augmented with snacks (MRPS))

randomized

trial. Participants were instructed to limit their total daily intake to 1200

(women) or 1500 (men) kcals. Those receiving the MR program were instructed not

to

snack while those in the MRPS program were told to snack three times per day.

SUBJECTS: A total of 100 participants were block-randomized, based on prestudy

snacking status (high vs low), to receive a standard meal replacement program

(MR)

or MRPS. MEASUREMENTS: Weight, height, blood pressure, lipid fractions, glucose,

and

insulin were assessed at the baseline, 12-, and 24 weeks. RESULTS: Completers

analysis at 24 weeks demonstrated a significant time effect (F(1,46)=44.6,

P<0.001),

indicating that all participants lost significant amounts of weight regardless

of

group assignment. An intention-to-treat model resulted in similar results. By

week

24, the average weight loss across groups was 4.6 kg. There also were

significant

improvements across all groups among completers for systolic blood pressure

(P=0.047), cholesterol (P=0.001), LDL (P=0.001), glucose (P=0.004), and insulin

(P=0.001) at week 12, and glucose (P=0.001) and insulin at week 24 (P=0.003).

CONCLUSIONS: Our results suggest that a participant's preferences for snacking

did

not affect their response to treatment. Snackers and nonsnackers responded

equally

well whether they received a standard meal replacement program or one augmented

with snacks.

Al Pater, PhD; email: old542000@...

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