Re: WBC and CRON?

[Guest guest]

Hi Geeta:

Naturally I cannot comment on the particular reason for **YOUR** low

WBC count. However, low WBC is typical of people on CRON. The

numbers you mention are not unusually low for a CRON practitioner.

Indeed, a low WBC count is one of many criteria some people use as

evidence of success in following a CRON diet.

The logic for the low reading may be that WBCs, which can be

produced 'to order' by the body in quantity when they are needed, are

simply not needed when inflammation and disease susceptibility are

much reduced as in CRON.

Rodney.

>

> I am a 42 year old male. I am running low WBC (and mildly low RBC)

for

> the last two years. The WBC is in the range of 2.5 to 3.4, with

> Neutrophils in the range of 1000 to 2000, Lymphocytes in the range

of

> 1000 to 1300, and Monocytes in the range of 100 to 180. I have

heard

> that this may be possible as a result of CRON (which I think is

what I

> am doing, though I did not know about CRON till very recently).

Even

> though I have had low WBC, I haven't had any major infections

during

> these two years, except some throat infections or mild fevers.

>

> Can some one share there experience on low WBC and CRON with me?

What

> are the long term consequences of having low WBC?

>

> Thanks

>

[Guest guest]

Agreed. My WBC # has been similiarly " low " for at

least 16 years. I very rarely get colds, GI " bugs, "

or any other common illnesses.

It has been suggested that our WBC #s are normal

and the standard " normal " is too high and may

be due to excessive inflammation due to chronic

ongoing low grade auto-immune inflammation in

those " overfed. "

On 7/22/06, Rodney <perspect1111@...> wrote:

Hi Geeta:Naturally I cannot comment on the particular reason for **YOUR** low WBC count. However, low WBC is typical of people on CRON. The numbers you mention are not unusually low for a CRON practitioner. Indeed, a low WBC count is one of many criteria some people use as evidence of success in following a CRON diet.The logic for the low reading may be that WBCs, which can be produced 'to order' by the body in quantity when they are needed, are simply not needed when inflammation and disease susceptibility are much reduced as in CRON. Rodney.>> I am a 42 year old male. I am running low WBC (and mildly low RBC) for > the last two years. The WBC is in the range of 2.5 to 3.4, with > Neutrophils in the range of 1000 to 2000, Lymphocytes in the range of > 1000 to 1300, and Monocytes in the range of 100 to 180. I have heard > that this may be possible as a result of CRON (which I think is what I > am doing, though I did not know about CRON till very recently). Even > though I have had low WBC, I haven't had any major infections during > these two years, except some throat infections or mild fevers.

> > Can some one share there experience on low WBC and CRON with me? What > are the long term consequences of having low WBC?> > Thanks>

[Guest guest]

Hi ,

Any idea what the mechanism is for "overfeeding" to excite inflammation?

I can guess too much protein oxidation?

Regards.

Re: [ ] Re: WBC and CRON?

Agreed. My WBC # has been similiarly "low" for at

least 16 years. I very rarely get colds, GI "bugs,"

or any other common illnesses.

It has been suggested that our WBC #s are normal

and the standard "normal" is too high and may

be due to excessive inflammation due to chronic

ongoing low grade auto-immune inflammation in

those "overfed."

..

[Guest guest]

Can only speculate. Possibly, overfeeding induces disorganized immune reaction, thus too many inflammatory processes occuring without direction.

On 7/22/06, jwwright <jwwright@...> wrote:

Hi ,

Any idea what the mechanism is for " overfeeding " to excite inflammation?

I can guess too much protein oxidation?

Regards.

Re: [ ] Re: WBC and CRON?

Agreed. My WBC # has been similiarly " low " for at

least 16 years. I very rarely get colds, GI " bugs, "

or any other common illnesses.

It has been suggested that our WBC #s are normal

and the standard " normal " is too high and may

be due to excessive inflammation due to chronic

ongoing low grade auto-immune inflammation in

those " overfed. "

..

[Guest guest]

I could not remember if this was posted

Inflamation, stress and diabetes

JCInvestig. may 2006 vol 115,5 pag 1111-1119

Regards

..

[Guest guest]

http://www.jci.org/cgi/content/full/115/5/1111?maxtoshow= & HITS=10 & hits=10 & RESULTFORMAT= & fulltext=diabetes+stress+inflammation & searchid=1 & FIRSTINDEX=0 & resourcetype=HWCIT

On 7/22/06, Orfilio Franco <carlosofranco@...> wrote:

I could not remember if this was posted

Inflamation, stress and diabetes

JCInvestig. may 2006 vol 115,5 pag 1111-1119

Regards

..

[Guest guest]

Thanks very much,

I notice the word adiponectin, a down regulator in Table 1.

And

Ref 23: Ouchi, N. et al. 2003. . Obesity, adiponectin and vascular inflammatory disease. Curr. Opin. Lipidol. 14::561-566.

Notice Figure 1. Role of adiponectin in inflammatory cascades

"Conclusion

Adiponectin is an adipocyte-specific adipocytokine with anti-inflammatory, anti-diabetic and anti-atherogenic properties. Adiponectin acts as an endogenous biologically relevant modulator of vascular remodeling through attenuation of excessive inflammatory responses in the vascular walls. Therapeutic approaches aimed at increasing plasma adiponectin concentrations or adiponectin tissue sensitivity could potentially be beneficial in preventing obesity-related diseases. Elucidation of the molecular and cellular mechanisms of adiponectin function should provide useful information about the pathogenesis of vascular disease."

Regards.

Re: [ ] Re: WBC and CRON?

http://www.jci.org/cgi/content/full/115/5/1111?maxtoshow= & HITS=10 & hits=10 & RESULTFORMAT= & fulltext=diabetes+stress+inflammation & searchid=1 & FIRSTINDEX=0 & resourcetype=HWCIT

On 7/22/06, Orfilio Franco <carlosofranco@...> wrote:

I could not remember if this was posted

Inflamation, stress and diabetes

JCInvestig. may 2006 vol 115,5 pag 1111-1119

Regards

..

[Guest guest]

Hi Geeta,You might want to read this article on anemia.  http://homepage.mac.com/chronart1/anemia.pdfIt is normal for CR people to have low WBC counts  -- all the people in the biosphere came out with low numbers.I watch this stuff more than most because I have LGL (Large Granular Lymphocytes) leukemia, T-Cell type.  It is not a fatal condition, near term, and I have probably had it since my blood work first began to look weird in 1990 but I was only diagnosed 2 years ago.  I am now 66 and doing great with no treatment.  I have only been practicing CR for a year and CR hasn't changed my blood numbers.  I kept reading articles like the one above and after pushing my doctors and then getting an oncologist involved I got a bone marrow essay with the diagnosis.  A low neutrophil count is another characteristic of LGL Leukemia.  Mine is between 1100 and 1300, it is only a problem if it gets down to 600.  Then every-time you get the flu you are hospitalized.  My life expectancy is more than 10 years, but they really don't know.I was also suspicious something was wrong when all my friends could play tennis every morning for an hour and I could only do it twice a week.What bothers me is that my hemoglobin is 1300 and people with this reading according to the above article live 10 years less than those at 1500.  I speculate that this low reading marginally accelerates aging.  I am trying to talk my doctors into a Procrit shot to see what happens but no luck yet.  Like in the article all the nutrients my body needs to make hemoglobin are there.  My bone marrow cells just don't make enough.  Once, in the mid 1990's I gave blood and regretted it for two months.Barry Gamble