Correlates of HIV vaccine trial participation: an Indian perspective

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Correlates of HIV vaccine trial participation: an Indian perspective

Vaccine 2005 Feb 3;23(11):1351-8 (ISSN: 0264-410X)

Sahay S; Mehendale S; Sane S; Brahme R; Brown A; Charron K; Beyrer

C; Bollinger R; Paranjape R

National AIDS Research Institute, G-73, MIDC, Bhosari, P.O. Box

1895, Pune 411026, India.

Successful conduct of HIV vaccine trials in a population of great

cultural diversity like India could be a challenge. Concerns,

knowledge gaps and willingness to participate in future HIV vaccine

trials were studied among 349 patients attending three sexually

transmitted infections clinics and one reproductive tract infections

clinic. Overall willingness to volunteer for HIV vaccine trials was

48%. Women and men at risk of HIV infection were willing to

participate in the HIV vaccine trials.

Factors associated with increased willingness to participate in

these trials were awareness of current HIV vaccine efforts,

realization of importance of vaccine for self, concern about adverse

events and altruism.