In Answer to Questions on Resveratrol [wasRe: Notice of Joint Bulk Purchase

[Guest guest]

> > > >

> > > > Note from Francesca: A recent study posted here claimed that

> > reservatrol

> > > > is NOT the main ingredient in wine that benefits longevity. Also

> > another

> > > > study that claims that reservatrol gives no further benefit to

> > those already

> > > > on CR. That said, I am myself on a trial of it purchased from

> the site

> > > > posted by Maco a few weeks back. I have been taking it for 2

> > months and

> > > > notice no difference in my energy level or otherwise. Maco's

site is

> > > > purityproducts.com and the capsules do not need refrigeration

orany

> > > > special handling unlike the bulk purchase that is proposing

> > below. It

> > > > also has special " deals " at the site and I paid a reasonable

price.

> > > >

> > > > Here is 's post:

> > > >

> > > > Notice of Joint Bulk Purchase of >99% Resveratrol

> > > >

> > > > Participants are being sought for a joint bulk purchase of

>99% pure

> > > > fully synthetic trans-resveratrol from the exact same company

> (Orchid

> > > > Chemicals and Pharmaceuticals Ltd of Chennai, India) that

> supplied the

> > > > resveratrol used in the last two major published mouse feeding

> studies

> > > > http://pmid.us/17086191 http://pmid.us/17112576. In these studies

> > > > trans-resveratrol, at human equivalent daily dosages of 5 and 50

> mg/kg

> > > > respectively, was shown to have major beneficial effects as a

> calorie

> > > > restriction mimetic, and on enhanced mitochondrial activity

> resulting

> > > > in more energy and stamina respectively. The pure synthetic

has the

> > > > advantage that it is completely free from plant contaminants

> which may

> > > > have negative effects, while being exactly the same chemical as

> occurs

> > > > in nature in red wine (among other sources). In order to obtain a

> > > > supply of trans-resveratrol for myself and other interested

> parties, I

> > > > am seeking others to join me in a large bulk purchase so that

> together

> > > > we may get the far lower price per gram that the supplier will

give

> > > > for a large order. I have already successfully received and

> > > > distributed to the initial joint purchase participants 4 kg from

> > > > Orchid which is in the process of producing a large new batch

to be

> > > > ready by mid March 2007. This notice is for the purpose of

> increasing

> > > > the amount that will be ordered at that time, if anyone should be

> > > > interested.

> > > >

> > > > Here are the terms of this add-on commitment for new joint bulk

> > > > purchase participants.

> > > >

> > > > Terms and Conditions of Joint Bulk Purchase as of Jan 18, 2007

> > > >

> > > > Pricing

> > > >

> > > > 100 grams @ $4.00 per gram,

> > > > 200 grams @ $3.65 per gram,

> > > > 300 grams @ $3.40 per gram,

> > > > 400 grams @ $3.25 per gram,

> > > > 500 grams @ $3.15 per gram.

> > > >

> > > > Packaging

> > > >

> > > > All purchases are packaged in 50 or 100 gm amounts in

polypropylene

> > > > (PP) zip-lock bags with all air expelled before the bag is

> closed. PP

> > > > bags are much more moisture and air proof than are

polyethylene (PE)

> > > > bags (the standard that one gets at the supermarket). Each PP

bag is

> > > > placed in a zip-lock PE sandwich bag for added protection.

Multiple

> > > > bags are then placed into a bubble envelope which is then placed

> > > > inside a USPS flat rate priority mail envelope for shipments

of 200

> > > > grams or less and a priority box for more than that. (For those

> > > > outside the US things will be done a little differently as

> appropriate

> > > > to your import needs.)

> > > >

> > > > Storage, handling and Dosage

> > > >

> > > > If the bags are kept in a freezer (all processes are slower at a

> lower

> > > > temperature), and inside a light proof container (dark bottle or

> HDPE

> > > > container), then research, reading and discussions with others

> > > > suggests that there will be little degradation over a period of 2

> > > > years. The mice researchers stated nothing about storage in

nitrogen

> > > > during the experiment and most of the storage time was in a

> > > > refrigerator mixed with chow. During actual usage everyone

would be

> > > > wise to expel all air from the bag whenever it is reclosed after

> > > > getting some out of it.

> > > >

> > > > When you remove some resveratrol from a larger package, only

remove

> > > > enough to last for, say, ten days or 2 weeks at a time and,

when not

> > > > in use, keep it in a small PP ziplock bag in a dark bottle in the

> > > > refrigerator. Small PP zip-lock bags will be enclosed with every

> > > > shipment package for the purpose of keeping this smaller in-use

> amount

> > > > in the refrigerator.

> > > >

> > > > As for dosage, standard dosage increasing procedures for any new

> > > > chemical suggests that it will be safest to start at 0.5 mg/kg

daily

> > > > and double every 2 weeks until you reach at least 5 mg/kg

(which is

> > > > what Dr Sinclair takes and what I am taking), but this is

> really

> > > > a matter of individual choice and desire for experimentation. With

> > > > respect to upper limits of dosage, note that there is no

evidence of

> > > > toxicity for resveratrol even at a human equivalent dosage of 75

> mg/kg

> > > > - http://pmid.us/15329443.

> > > >

> > > > Shipping and payment

> > > >

> > > > All prices include priority mail (USPS) shipping to US addresses

> and a

> > > > copy of the Certificate of Analysis (COA) of the product.

> > > > Insurance of package costs extra.

> > > > Out of US shipping incurs a $25 surcharge (only $15 to Canada)

> with no

> > > > customs entry guarantees.

> > > > Email me your full legal name, physical and postal addresses,

phone

> > > > number and amount desired.

> > > > Be prepared to pay in advance by check or money order in early

March

> > > > when the next order with Orchid will need to be placed and

prepaid,

> > > > since this is a joint bulk purchase and must be prepaid.

> > > > I will email you when I need prepayment in March.

> > > >

> > > > Responsibility for Loss

> > > >

> > > > Everyone should be aware that although all joint purchasers

received

> > > > their allotted share of the first partial shipment, there is

always

> > > > some possibility that an entire future shipment, or merely a

> shipment

> > > > to a particular joint purchaser, will be lost. Although as the

> > > > coordinator of this prepaid joint bulk purchase I promise to do

> > > > everything that I possibly can to prevent any such loss, I do

> not bear

> > > > any responsibility for refunding any money in the case of any such

> > loss.

> > > >

> > > > -- Wakfer

> > > >

> > > > MoreLife for the rational - http://morelife.org

> > > > Reality based tools for more life in quantity and quality

> > > > The Self-Sovereign Individual Project - http://selfsip.org

> > > > Rational freedom by self-sovereignty & social contracting

> > > >

> > > >

> > > >

> > >

> >

>