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Early Menopause

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This seems to be the million dollar question Iris. As far as I've

seen, there doesn't seem to be any medical articles to support early

menopause or any hormonal problems with women on Gleevec however if you

ask the women who are on Gleevec, there are just too many that are

having one issue or another to ignore the fact that there does seem to

be some hormonal issues going on.

Over the years I've seen plenty of women complain about irregular

periods, heavy periods, and missed periods so I can't help but think

something hormonal must be going on.

I went through a period of about 18 months where my prolactin level was

very high and I went through extensive testing to try to figure out why

but nothing was ever found that could cause it to rise the way it did.

The only studies I've seen that come close to dealing with hormonal

issues are ones that were done on men who had developed breasts while

on Gleevec (gynecomastia). The theory is that Gleevec can reduce

testosterone levels which can then cause men to grow breasts but I

haven't seen any studies done on women. Testosterone isn't really

something that women have a big problem with even if it does go a bit

low :)

So I guess what I'm saying is that no one can say for sure that Gleevec

causes hormone problems but if you go by anecdotal stories, there's no

doubt in my mind that there is a link.

Take care,

Tracey

>

> Does anyone know whether CML/ Gleevec can bring about early menopause?

>

> Iris

>

>

>

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