Rising Fish Levels

[Guest guest]

Hi everyone,

I have been reading your posts for several months now and take great

comfort in everything I read. My husband was diagnosed with CML in

August of 2006. He has been on 400 mg of Gleevec daily and was doing

great. His FISH level at diagnosis was 189, then in October 06 the

level was 124 then in December 06 it was 14. We were thrilled. Then

in Febuary 2007 his FISH was 22. The Dr. wanted the FISH repeated

which we did and today April 11th the FISH was 35. I can't tell you

how our hearts sank. Has anyone else encountered this? We are still

waiting for our PCR test to come back but have nothing to compare it

to as the DR. didn't order one initially. We are waiting for an

appointment at the Hospital of University of Pennsylvania to speak

with a transplant specialist for evaluation.

On top of everything my husband also takes anti-siezure medication for

epilepsy. (The summer of 2006 was not a good one for us) Does Keppra

interact with Gleevec? The Dr. says " No " but I would like to hear any

comments you all may have.

Sorry for the long message. My prayers are will all of you as well as

for my husband and family. Thank you for any information.

D