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Coumadin and the G herbs

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Acknowledgement of Support

Supported by an educational grant from Sucampo Pharmaceuticals, Inc,

and Takeda Pharmaceuticals North America, Inc..

ACP: Garlic, Ginseng, Ginkgo Biloba, and Ginger All Bad Actors with

Coumadin

 

By Peggy Peck, Managing Editor, MedPage Today

Reviewed by Jasmer, MD; Assistant Professor of Medicine,

University of California, San Francisco

April 09, 2006

MedPage Today Action Points

• Explain to patients who ask that vitamins, as well as so-called

natural substances, can react with prescription drugs.

• Explain to patients who ask that periodic review of all

prescription and non-prescription drugs that they are using can reduce

the risk of adverse events.

Review

PHILADELPHIA, April 9 - When it comes to adverse events associated

with Coumadin (warfarin) therapy, beware of herbs and many supplements

beginning with the letter G, according to a University of Washington

investigator.

S. Paauw, M.D., spelled them out for a standing-room-only crowd

at the American College of Physicians meeting here. They are garlic,

ginger, gingko biloba, and ginseng.

" Garlic, ginger, and gingko biloba all increase the anticoagulation of

warfarin [Coumadin], while ginseng can decrease it, " he said.

Adverse events associated with Coumadin therapy continue to be a

leading cause of hospitalizations for drug-related adverse events, and

many times the problem can be traced to those herbs and supplements, he

said. Dr. Paauw ran through those and other hazards during a session

titled, " Ten Common Prescribing Errors: Drug Interactions and Side

Effects. "

http://www.medpagetoday.com/2005MeetingCoverage/ACP/dh/3050

Sears

PDX

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