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FISH and PCR tests

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I know that I have asked this question already but I lost my responses.

I have been on Gleevec for almost four months and reached cytologic remission

last month. My doctor drew some additional blood this past week to now conduct

a FISH test and do a PCR for the BCR-ABL protein..

Can someone please remind me the difference between the two tests and why we

do both.

Also, my doctor told me that you can be FISH negative but still have the

BCR-ABL protein in your body. Can someone please elaborate on that and explain

how that is possible, and whatthat means as far as remission.

Thank You

Efrem

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