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Re: Tasigna- Tim

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Hi Tim,

Thanks for giving us a great summary of the side effects for AMN-107.

Can you give any more detail about the anomalies that were found

regarding the pancreas? Which lab tests did they do to monitor it? I

assume that pancreatitis wasn't the issue since you said that most of

the patients didn't have any physical symptoms? Do you know if the

patient's lab results returned to normal after they discontinued taking

the drug?

Thanks for your input,

Tracey

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Do you know if the

> patient's lab results returned to normal after they discontinued

taking

> the drug?

Tracey,

I have heard a few reports that they did return to normal. I believe

that there is a clinical trial that was recently started to evalute

this further. Not much else to report right now.

Skip,

I am glad that you are doing well on Nilotinib. I did not mean to

imply that you had said anything out of bounds about this drug. I

merely was objecting to 's Oncologist statement that it was safer

than Gleevec. I have heard this opinion long before any of the trial

results were out on the drug. Hopefully, the Oncology community will

get up to speed once the drug is approved.

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ok Tim

I have survived when there were no drugs for CML,

or at least just one which was Myleran, and I never

did

understand nor did the doctors how I survived over

all these years.. So for me to say any drug was better

or more effective would be a lie. All I know is that

I am still around.. Still taking new drugs

ie. Exjade and nilotinib..BTW nilotinib is still the

name that my onc uses as well as the people from my

trial and Novartis.

thank Skipd

my diary of blood counts on AMN107

http://easyskip.tripod.ca

--- <timothyfarley16@...> wrote:

> Do you know if the

> > patient's lab results returned to normal after

> they discontinued

> taking

> > the drug?

>

> Tracey,

>

> I have heard a few reports that they did return to

> normal. I believe

> that there is a clinical trial that was recently

> started to evalute

> this further. Not much else to report right now.

>

> Skip,

>

> I am glad that you are doing well on Nilotinib. I

> did not mean to

> imply that you had said anything out of bounds about

> this drug. I

> merely was objecting to 's Oncologist statement

> that it was safer

> than Gleevec. I have heard this opinion long before

> any of the trial

> results were out on the drug. Hopefully, the

> Oncology community will

> get up to speed once the drug is approved.

>

>

>

SkipD

Dx'ed Dec 1978

on Myleran(busulfan) 26 yrs

on Hydroxyurea for about 1 year

on Gleevec for approx 1.5 years

on AMN107(Nilotinib) to now

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