Does anyone know if monocytosis is worrisome or not?

[Guest guest]

Hi. I was diagnosed with CML three years ago; have been on Gleevec

all that time - never reached 0% PH chromosome.

I went for my checkup the other day, and my blood was checked via

the " quickie " blood machine in the office. My monocytes are over

17% - something new, not a problem before. Total WBC is normal at

this point.

When the doctor came in, she said, " Are you still taking your

Gleevec? " Well, of course I am. She stated that we have to see if

the Gleevec is still working.

Well, it always takes some time to get the PCR results, and I am

wondering, is this monocytosis a problem or not? I do know that

monocytes over 15% are supposed to be extremely high. Could

monocytosis be a sign that the CML is becoming Gleevec resistant?

Also, supposing Gleevec isn't working anymore, what else is there? I

tried Sprycel because of Gleevec side effects, but I developed angina

from the Sprycel (never had any heart issues before or since

Sprycel).

Grace