Re: Need some help -- Drug Interactions In Imatinib Therapy

[Guest guest]

yusef,

I have had the same problem. Don't worry abou the antibiotic. It just

enhances the Fleevec, makes it stronger. You wil only be one it for about 10

days. You really need the treatment, as it can get worse and become more

painful.

Yusuf Cipe <cipeyusuf@...> wrote:

Hello all,

For a while i'm having some trouble with my stomach. Endoscopy results shows

that there is bacterium called helicobacter pylori in my stomach which causes

serious stomach problems. So my doctor told me to begin an antibiotics therapy

for a week which contains 1000 mg clarithromycin every day. I asked him if there

is an interaction between gleevec and this antibiotics and his answer was " no " .

The problem is that i searched the web and read that there is an interaction

between imatinib and clarithromycin. I'm really confused now and i dont know

what to do. I will be very happy if someone has a knowledge or idea about this.

http://medicineworld.org/cancer/lead/2-2006/drug-interactions-in-imatinib-therap\

y.html

http://www.drugs.com/mtm/gleevec.html

Thank you very much.

Yusuf Cipe

Istanbul

---------------------------------

oneSearch: Finally, mobile search that gives answers, not web links.

[Guest guest]

Hi Yusuf,

The interaction between Gleevec and Clarithromycin will cause the

Gleevec level in your system to rise. Are you taking 400mg or

higher? If you are on 800mg, you may want to talk to your doctor

about reducing your Gleevec dose (to 600mg or 400mg) during the time

you will be taking the antibiotic but if you are on 400mg and

tolerating it well, you shouldn't have a problem, especially if the

duration of the antibiotic is only a week.

Good luck,

Tracey

>

>

> Hello all,

>

> For a while i'm having some trouble with my stomach. Endoscopy

results shows that there is bacterium called helicobacter pylori in

my stomach which causes serious stomach problems. So my doctor told

me to begin an antibiotics therapy for a week which contains 1000 mg

clarithromycin every day. I asked him if there is an interaction

between gleevec and this antibiotics and his answer was " no " .

>

> The problem is that i searched the web and read that there is an

interaction between imatinib and clarithromycin. I'm really confused

now and i dont know what to do. I will be very happy if someone has a

knowledge or idea about this.

>

> http://medicineworld.org/cancer/lead/2-2006/drug-interactions-in-

imatinib-therapy.html

>

> http://www.drugs.com/mtm/gleevec.html

>

> Thank you very much.

>

> Yusuf Cipe

>

> Istanbul

>

>

> ---------------------------------

> oneSearch: Finally, mobile search that gives answers, not

web links.

>

>

[Guest guest]

this is steve not yusef

---------------------------------

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[Guest guest]

Hello Yusef,

My sister has CML (400 ml daily) and is recovering from colon cancer surgery

(Sept. 2006). When I read your post, I felt like she had written it. One month

ago, she also was diagnosed with the bacteria H -Pylori and given that

same medication. Two weeks later, she became very ill. She had flu like

symptoms at first and then suddenly lost all control of bowels movements. She

has

to be hospitalized and was diagnosed with a very serious disease called C.

diff (google that). She was on IV's for a long time. This is such a hard

contagious medical adverse reaction for the body to handle. Hospitals do not

like to have patients sick with c-diff..it travels fast. She is recovering

slowly, but anyone who has ever heard of this disease knows that this takes a

long time and it is very serious.

We know that everyone reacts differently to medications based on their

own health at the time. We don't know if this was a drug interaction with

Gleevec or what, but, we urge you to do just what the Internet recommendation

says:

Monitor for adverse events.

Sincerely,

Jan

janw815@...

**************************************

Get a sneak peek of

the all-new AOL at http://discover.aol.com/memed/aolcom30tour

[Guest guest]

Hi Jan,

I'm sorry to hear about your sister's struggles and I hope she

recovers very soon.

C Difficile is a bacteria that you acquire, usually after you've been

on antibiotics for a while and usually when a patient has been in a

hospital where the bacteria is present. It's not something that you

get from a drug interaction between Gleevec and an antibiotic, it's a

bacteria that you catch.

I wish you and your sister the best,

Tracey

>

> Hello Yusef,

> My sister has CML (400 ml daily) and is recovering from colon

cancer surgery

> (Sept. 2006). When I read your post, I felt like she had written

it. One month

> ago, she also was diagnosed with the bacteria H -Pylori and

given that

> same medication. Two weeks later, she became very ill. She had

flu like

> symptoms at first and then suddenly lost all control of bowels

movements. She has

> to be hospitalized and was diagnosed with a very serious disease

called C.

> diff (google that). She was on IV's for a long time. This is

such a hard

> contagious medical adverse reaction for the body to handle.

Hospitals do not

> like to have patients sick with c-diff..it travels fast. She is

recovering

> slowly, but anyone who has ever heard of this disease knows that

this takes a

> long time and it is very serious.

> We know that everyone reacts differently to medications

based on their

> own health at the time. We don't know if this was a drug

interaction with

> Gleevec or what, but, we urge you to do just what the Internet

recommendation

> says:

> Monitor for adverse events.

> Sincerely,

> Jan

> janw815@...

>

>

> **************************************

> Get a sneak peek of

> the all-new AOL at http://discover.aol.com/memed/aolcom30tour

>

>

>