Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Tracey: I have had continual changes in my vision the last two years and I have been going to the optometrist every 6 months. Because of the pressure issue, I make sure they check it each time and my pressure has not been an issue. However, you have been on Gleevec much longer than I have. Sincerely, Matt ville, Florida Dx January of 2005 Gleevec since March of 2005 Treated at MD Father of 3 In a message dated 7/11/2007 7:43:27 A.M. Eastern Standard Time, traceyincanada@... writes: Hi Everyone, Some time ago I posted an abstract that showed the various side effects that Gleevec could cause on the eyes and an increase in intraocular pressure was one of them. Well I finally got around to getting my eyes tested and sure enough, my pressure was quite high. Now I'm curious to know if anyone else has kept on " eye " on their eye pressure. Unfortunately, I can't say for sure that the Gleevec is at the root of my eye pressure because I don't think I ever had it tested prior to starting Gleevec over 5 years ago. If I did, it would have been with a different eye doctor, in a different province so it wouldn't be that easy for me to check anyway. It is possible that I've always been that way I guess. Tracey ************************************** See what's free at http://www.aol.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Hi dxt 12/23/05 eye tested May 07 pressure ok.I asked about the wet eyes,not much comment I did have a plug removed from tear gland.It was installed for dry eyes ,not anymore. ----- Original Message ________________________________________________________________________________\ ____ Shape in your own image. Join our Network Research Panel today! http://surveylink./gmrs/_panel_invite.asp?a=7 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 12, 2007 Report Share Posted July 12, 2007 Hi , I started on Gleevec in Dec of 2005 and in Oct 2006 I started noticing some blurred vision. I went to my ophthalmologist and I was diagnosed with pseudo tumor cerbri which in laymen' s terms is elevated spinal fluid pressure. This pressure was causing my optic nerves to swell causing my blurred vision. My onc. took me off Gleevec and the pressure came back down. I was started on Sprycel in Dec of 2007 and in May my elevated pressure is back. I have had two spinal taps that showed the elevated pressure. Right now I am off the Sprycel on a " drug holiday " and I have another appointment with my ophthalmologist on July 20th to see what the progress is. My dilemma is if Gleevec and Sprycel both are causing my elevated spinal pressure I think I am running out of options. I hope this information helps you, Chuck Talk to you soon, Chuck --------------------------------- Now that's room service! Choose from over 150,000 hotels in 45,000 destinations on Travel to find your fit. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 12, 2007 Report Share Posted July 12, 2007 Hi Chuck, I'm sorry to hear that Gleevec and Sprycel are causing your spinal fluid pressure to increase. Please don't worry that you're running out of options though. Nilotinib (AMN-107) should be approved shortly and so far it seems that this drug isn't having the same problems with fluid retention and edema that Gleevec and Sprycel have. There are also a myriad of other drugs in various trials around the US so there are still a number of options out there, should you need more choices. So far, my increase in intraocular pressure isn't serious enough to warrant a change in treatment but it's something my optometrist wants to keep a close " eye " on. It seems to be stable though so that's reassuring and thankfully, my actual vision hasn't been impacted. All the best to you, Tracey > > Hi , > I started on Gleevec in Dec of 2005 and in Oct 2006 I started noticing some blurred vision. I went to my ophthalmologist and I was diagnosed with pseudo tumor cerbri which in laymen' s terms is elevated spinal fluid pressure. This pressure was causing my optic nerves to swell causing my blurred vision. My onc. took me off Gleevec and the pressure came back down. I was started on Sprycel in Dec of 2007 and in May my elevated pressure is back. I have had two spinal taps that showed the elevated pressure. Right now I am off the Sprycel on a " drug holiday " and I have another appointment with my ophthalmologist on July 20th to see what the progress is. My dilemma is if Gleevec and Sprycel both are causing my elevated spinal pressure I think I am running out of options. > I hope this information helps you, > Chuck > > > Talk to you soon, > Chuck > > > --------------------------------- > Now that's room service! Choose from over 150,000 hotels > in 45,000 destinations on Travel to find your fit. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 12, 2007 Report Share Posted July 12, 2007 Hi , It's funny you should say this because I too used to have terribly dry eyes (before Gleevec). I still have an occasional day here or there where my eyes are dry (mostly in the winter when it's drier) but for the most part, Gleevec has fixed my dry eye problem. Sometimes they tear so much it looks like I'm crying. Tracey > > Hi dxt 12/23/05 eye tested May 07 pressure ok.I asked about the wet eyes,not much comment I did have a plug removed from tear gland.It was installed for dry eyes ,not anymore. > > > ----- Original Message > > > > ______________________________________________________________________ ______________ > Shape in your own image. Join our Network Research Panel today! http://surveylink./gmrs/_panel_invite.asp?a=7 > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 12, 2007 Report Share Posted July 12, 2007 Hi Chuck, Tracey, and , I have had different reactions with my eyes since beginning treatment on 400mg's of Gleevec in April of 04. When I first started taking it my eyes would swell nearly shut(looked like I had gotten out of the ring with Mike Tyson..lol) that gradually went away and once in a while they get puffy but that goes away as the day goes on. I wear contact lenses and have had dryness as well as the tearing up thing happen. I was wondering though Chuck what dosage level did they have you on when taking Gleevec? If it was over 400mg's you might want to just lower the dosage and see if they helps. I know many are jumping off the Gleevec bandwagon for these new drug coming out but from my understanding these drugs were suppose to be for people to take if they could not handle Gleevec or it stopped working? Anyway good luck and keep us posted on how your doing. Terry On 7/11/07, Tracey <traceyincanada@...> wrote: > > Hi , > > It's funny you should say this because I too used to have terribly > dry eyes (before Gleevec). I still have an occasional day here or > there where my eyes are dry (mostly in the winter when it's drier) > but for the most part, Gleevec has fixed my dry eye problem. > Sometimes they tear so much it looks like I'm crying. > > Tracey > > > > > > Hi dxt 12/23/05 eye tested May 07 pressure ok.I asked about > the wet eyes,not much comment I did have a plug removed from tear > gland.It was installed for dry eyes ,not anymore. > > > > > > ----- Original Message > > > > > > > > > __________________________________________________________ > ______________ > > Shape in your own image. Join our Network Research Panel > today! http://surveylink./gmrs/_panel_invite.asp?a=7 > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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