Re: Major Molecular Response -

[Guest guest]

,

I paid $506 for each PCR at OHSU. However, there was a recent increase

to $521.

Your onc will know the lab Kaiser uses for PCRs.

You can also get a copy of the PCR report from your husband's onc. The

report will state the lab. Then you can contact the lab if you want

more information.

I was with Kaiser for 30 years but felt more comfortable going to a

comprehensive cancer center after diagnosis. That's why I switched to

UCSD. Before the switch I asked UCSD about the PCR sensitivity and was

told that it was 1:100,000. Wrong! So it was quite a shock to get my

first PCR result in January and find out the sensitivity was only

1:1000. I no longer think it was necessary to have left Kaiser!

I have seen Dr. Druker twice. Yes, it is definitely an additional

expense, but worth it.

My best to you and your husband,

JoAnn

> > > >

> > > > Hi Mark and Marcos,

> > > >

> > > > Anytime a number is that low it's a good thing but I'm not

sure how

> > > > significant it is if the PCR's sensitivity was only 1 in 1,000.

> > > >

> > > > By definition, the famous 3 log reduction that we're all

aiming for

> > > > (which is how they define a major molecular response) , is a

> > > > reduction in transcripts by 1000 fold. Now if someone is still

> > > > positive on a test that only has a sensitivity of 1,000, would

that

> > > > not mean that their reduction is less than a 1000?

> > > >

> > > > As I've stated in previous posts, math is hardly my strong

suit but I

> > > > do know that the experts have said that PCR's with

sensitivities of

> > > > less than 1 in 100,000 are unreliable and give little information.

> > > >

> > > > Mark, I would suggest that you ask if you can send your samples to

> > > > another lab where they do more sensitive testing and this way

you'll

> > > > know exactly where you stand.

> > > >

> > > > Tracey

> >

>

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