Re: Remeron and Gleevec - interactions - xanax

[Guest guest]

I just wanted to add that recently I found that Xanax is supposed to

interact with Gleevec.

How exactly, I don't know. But what I do know is I have been taking xanax

for 7 years and Gleevec for 6 and I don't have any problems with anything

that I know of and I also recall many other people on the list taking the

same anxiety drug years ago when I was diagnosed. 2000

I am not saying this to say it's ok to take other drugs that interact with

Gleevec as I check everything first. But I would like to know exactly how it

does or could interact with xanax?

It also did not appear that all benzodiazepines interact with Gleevec.

ez

[Guest guest]

Hi ,

You're right, not all the benzodiazepines interact with Gleevec but

Xanax is one that does. The reason that Xanax interacts is because

it is metabolized using the P450 3A cytochrome.

http://www.drugs.com/pro/xanax.html

Gleevec is a potent inhibitor of CYP3A4 which means that it can

increase the plasma concentrations of the Xanax to potentially toxic

levels.

Ativan and Restoril are two examples of benzodiazepines that don't

interact with Gleevec. This is because they are metabolized mostly

through glucorinidation.

Hope that answers your question,

Tracey

>

> I just wanted to add that recently I found that Xanax is supposed to

> interact with Gleevec.

>

> How exactly, I don't know. But what I do know is I have been taking

xanax

> for 7 years and Gleevec for 6 and I don't have any problems with

anything

> that I know of and I also recall many other people on the list

taking the

> same anxiety drug years ago when I was diagnosed. 2000

>

> I am not saying this to say it's ok to take other drugs that

interact with

> Gleevec as I check everything first. But I would like to know

exactly how it

> does or could interact with xanax?

>

> It also did not appear that all benzodiazepines interact with

Gleevec.

>

>

>

>

>

> ez

>

>

>

>

>

>