Re: Starting Sprycel today!

[Guest guest]

, thanks for the updates. I will be real interested to see how things

go on Sprycell. My Onc and I have talked about it, whoa, by name. Not just

" other " options if my counts stay off. But, right now, things are great on

Gleevec, well, this month, haha.

Chris

************************************** See what's free at http://www.aol.com.

[Guest guest]

:

We are all hoping that things go well and believe that indeed

they will. Keep us updated as to his progress as I am sure

there are some of us who will eventually have to make that switch.

It is also good to hear that he returned to normal, if only for a

while. Maybe you will see more of that with Sprycel.

Sincerely,

Matt

ville, Florida

Dx January of 2005

Gleevec since March of 2005

Treated at MD

Father of 3

In a message dated 6/28/2007 12:23:48 P.M. Eastern Standard Time,

weez_555@... writes:

Hi all---

just called me and has his Sprycel in-hand! He is starting today,

140mg/day. Actually, was downing his first pill right when he hung up with

me. His liver counts have returned to " normal " from being off the Gleevec,

and now we start this new journey. We still have our appt at the end of the

month with Dr. Druker, so hopefully July proves to be a good month -

starting Sprycel and getting to meet with Dr. Druker! His onc will also be

monitoring him weekly for the first month or so. Actually, today is

Thursday, she is checking his counts, etc. come again Monday!

Funny, because he has been off Gleevec (no meds at all), for almost a month

now, and for a brief period of time, I had my " old husband " back. He felt

awesome the whole time, his WBC stayed at around 4500 the whole time, no

fatigue, no headaches, tons of energy, and didnt have to gourge himself at

meal time, since he wasnt taking Gleevec!! He spent the last couple weeks

cleaning the backyard, his garage, working on his 53 Chevy....all in

preparation for possible Sprycel side affects that may knock him down for

the first little while. But, we both know, that I can never have my " old

husband " back..he has CML and without these drugs, my " old husband " would

not be around for very long. So, we welcome Sprycel into our lives now, and

I now have my " new and imrpoved " husband...sometimes a little less energy,

sometimes a little more " achy " , but a whole lot more appreciative of life in

general, and the blessings we can now see clearly...these drugs being a

couple of those blessings.

So--I will be posting Spyrcel updates from time to time...thanks to all who

have already given us lots of Sprycel heads-ups...

Cervera

wife of Cervera, age 34

Diagnosed 7/2006

Was on 400mg/Gleevec daily, stopped due to liver interolerance

Started 140mg/Sprycel daily on 6/28/07

__________________________________________________________

Who's that on the Red Carpet? Play & win glamorous prizes.

_http://club.http://clhttp://clubhttp://club.http://club.<WBhttp://club.<WBR_

(http://club.live.com/red_carpet_reveal.aspx?icid=REDCARPET_hotmailtextlink3)

************************************** See what's free at http://www.aol.com.

[Guest guest]

, did you all ever get some sort of answer from the Onc or maybe ask Dr

Druker why all of a sudden did start to reject Gleevec? Was it just

his liver saying no more, could the weekend with the oysters and brew have

contributed? Just curious.

Chris

************************************** See what's free at http://www.aol.com.

[Guest guest]

Hi---

It was liver intolerance. No, the oysters and brew maybe had something to do

with it happening THAT day, but, no--that is not why he went off Gleevec. He

hasnt had any alcohol for about 6 weeks now. He was off Gleevec for 3 weeks,

and his liver recovered to normal. He started Gleevec at a reduced dose

(300mg), and within just 5 days it shot back up to 5x the toxicity rate -

and he still was not drinking alcohol, taking tylenol or doing anything that

would make his liver angry! So, his onc felt that he could keep starting and

stopping Gleevec and the same result would happen. So, she (along with us),

decided it was time for the switch.

He is on day 2 of Sprycel, and the later half of today has felt pretty

good--just a little tired. Yesterday was crazy - rashes, hives, headaches,

swollen eyes and lips, and then it all went away. So--tomorrow is day

3...we'll see what day 3 holds.

Take care,

>From: letitbe@...

>Reply-

>

>Subject: Re: [ ] Starting Sprycel today!

>Date: Fri, 29 Jun 2007 18:11:44 EDT

>

>, did you all ever get some sort of answer from the Onc or maybe ask

>Dr

>Druker why all of a sudden did start to reject Gleevec? Was it just

>his liver saying no more, could the weekend with the oysters and brew have

>contributed? Just curious.

>

>Chris

>

>

>

>************************************** See what's free at

>http://www.aol.com.

>

>

>

[Guest guest]

Thanks for the update and response, . I was just curious. I have had

a couple beers as my Onc said I could. He said my liver tox was completely

normal. Been on Gleevec for 4 months now, just was worried I might be messing

with a good thing. But, am watching the alcohol intake. Like two per

month, nothing major.

Hope the new side effects go away fast.

My headaches have started back now since off the Topamax. But, to have my

blood counts back normal, I can live with that.

Chris

************************************** See what's free at http://www.aol.com.