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Tasigna

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I had great difficulty with the GI side effects of Gleevec and begin

a regimen of Tasigna last November. I have found that most of the

GI issues that I had with Gleevec have promptly disappeared.

Tasigna is taken twice a day on an empty stomach, at least two

hours after a meal or one hour. At the beginning this is kind of

hard to schedule, but I take my doses at the time I get up and

at approximately 5:00 in the afternoon. The standard dose

is 400 mg twice a day, however some are on 200 mg twice

a day. I have also heard of people taking 400 mg once a day.

I did have one scare and ended up in the ER with high pancreatic

enzymes and low electrolytes. I know drink at least two 8 oz.

glasses of Gatorade each day and supplement with electrolyte

tablets that I obtain from Hammer Gel nutrition.

For those of you with significant GI issues with Gleevec, I would

encourage you to consider Tasigna as I have done well on it

so far.

With warm regards,

Matt

ville, FL

DX January 2005

Gleevec March 2005

Tasigna November 2008

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