Can someone please help me with my FISH results

[Guest guest]

Hi,

I am confused about my FISH results and was hoping some of the great people on

the board can help interpret the reults. They are as follows: Interphase

cells:200

Peripheral Cells:0

FISH results: Negative for 16q22 rearrangement by FISH nuc ish (CBFBx2) (200)

Interpretation and Comments:

The FISH study showed no evidence of a CBFB (16q22) rearrangement, inv(16) or

t(16;16), seen in acute myelomonocytic leukemia with eosinophilia, less commonly

in other forms of acute myeloid leukemia, and rarely myelodysplastic syndrome. A

normal hybridization signal was detected in more than 98% of onterphase cells

analyzed. To be considered positive, a " break apart " FISH pattern should be

detected in 3% or more cells. This test will not detect other cytogenetic

abnormalities that may have clinical significance. These reults should be

considered incomonation with other standard cytogenic results as well as other

clinical and hematological data.

Here is why I am confused. What does 16 and 22 have to do with this? I thought

they were looking for 9 and 22? I think this is very good news, but I am

confused about the whole 16/22 thing. Someone please help. Thanks,

D

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