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Re: Re: PCR result

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Beside what Tracey already said, there is no reason to consider a stem

cell or bone marrow transplant when gleevec is working, even for

younger people. The risk and impact on quality of life of a transplant

is without comparison with staying on gleevec as long as it works. The

drug is now proven to be effective in the long term and the side

effects are minimal for most people. And we can hope for a cure in the

next decade. With a transplant you are at best exchanging the leukemia

against graft versus host disease, which even when it is low grade,

impacts quite a bit on quality of life. And it is for ever. It took me

one year to reach the level of remission you had in 3 months, and I am

still not at 3 logs after 3 years, but the numbers are still slowly

decreasing and I am staying at 400mg/day. I am 41 and doing great.

Side effects went away after a few months, hang in there.

Cheers,

Marcos.

On Feb 19, 2008 5:33 AM, Malseed <rodorbal@...> wrote:

>

>

>

>

> Hi Marcos and Tracey,

>

> Thank you for your kind words and words of wisdom I like you will question

> further if I am to up my dose rate - I think the main reason is that by not

> increasing the dose, it may be possible to get mutations down the track? As

> I said the Australian way seems to be to keep upping the dose to 800mg. I'm

> positive I will never cope with this.

>

> As always, once you get home you have more questions to ask and this group

> is so helpful. My haem/t also brought up that as I am doing so well and so

> young still at 50 <huge grin, I love that man> that I should also give

> thought to going down the donor track....now that is something I am not at

> all keen about and very risky, while we have these excellent drugs coming

> along.

>

> To top my good week off, my daughter had her 2nd baby a little boy, so it

> has been lovely babysitting my nearly 2 year old grand daughter and visiting

> mum and bub in hospital.

>

> Regards,

>

>

>

> _____

>

>

>

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I agree with you 100%

Marcos Perreau Guimaraes <montereyunderwater@...> wrote: Beside

what Tracey already said, there is no reason to consider a stem

cell or bone marrow transplant when gleevec is working, even for

younger people. The risk and impact on quality of life of a transplant

is without comparison with staying on gleevec as long as it works. The

drug is now proven to be effective in the long term and the side

effects are minimal for most people. And we can hope for a cure in the

next decade. With a transplant you are at best exchanging the leukemia

against graft versus host disease, which even when it is low grade,

impacts quite a bit on quality of life. And it is for ever. It took me

one year to reach the level of remission you had in 3 months, and I am

still not at 3 logs after 3 years, but the numbers are still slowly

decreasing and I am staying at 400mg/day. I am 41 and doing great.

Side effects went away after a few months, hang in there.

Cheers,

Marcos.

On Feb 19, 2008 5:33 AM, Malseed <rodorbal@...> wrote:

>

>

>

>

> Hi Marcos and Tracey,

>

> Thank you for your kind words and words of wisdom I like you will question

> further if I am to up my dose rate - I think the main reason is that by not

> increasing the dose, it may be possible to get mutations down the track? As

> I said the Australian way seems to be to keep upping the dose to 800mg. I'm

> positive I will never cope with this.

>

> As always, once you get home you have more questions to ask and this group

> is so helpful. My haem/t also brought up that as I am doing so well and so

> young still at 50 <huge grin, I love that man> that I should also give

> thought to going down the donor track....now that is something I am not at

> all keen about and very risky, while we have these excellent drugs coming

> along.

>

> To top my good week off, my daughter had her 2nd baby a little boy, so it

> has been lovely babysitting my nearly 2 year old grand daughter and visiting

> mum and bub in hospital.

>

> Regards,

>

>

>

> _____

>

>

>

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