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Interferon after Gleevec

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I found this one really interesting.

A new study is underway to determine if patients can go off of Gleevec

and onto a low dose of Interferon if they can achieve PCRU while on

Gleevec and maintain that response for at least a year.

Four patients were studied in this abstract, all had achieved PCRU

while on Gleevec and maintained that for a year, then stopped taking it

and started taking a low dose of Interferon. All of them were still

PCRU after between 3 and 12 months of being off Gleevec and taking only

Interferon.

Interferon works differently than Gleevec does so it's possible that

Interferon may be able to handle the minimal residual disease better

than Gleevec to eradicate those last stubborn quiescent cells.

http://www.abstracts2view.com/hem07/view.php?nu=HEM07L1_342 & terms=

Tracey

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