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It is also glivec in France and most Europe. They must have learnt as

Tasigna (also by Novartis) has about the same pronunciation

everywhere.

Marcos.

On Fri, Feb 22, 2008 at 5:56 PM, Tracey <traceyincanada@...> wrote:

>

>

>

>

> As most drugs have a couple of names, it can get very confusing when

> trying to determine which are the same so here's a break down of the

> three most common drugs used for CML now:

>

> Gleevec is also called Glivec (in the UK) Imatinib, and STI571

>

> Sprycel is also called Dasatinib, and BMS-354825

>

> Tasigna is also called Nilotinib and AMN-107

>

> The first name is the brand name, the second name is the generic name

> and the third name is the name the drug was given in the first trials

> before it was approved.

>

> Gleevec is different than the rest because it actually has two brand

> names (Gleevec and Glivec). The reason is because Novartis was

> worried that North American's wouldn't be able to pronounce it

> properly if they called it Glivec so they changed the spelling to be

> more phonetically accurate.

>

> Tracey

>

>

--

Marcos Perreau Guimaraes

Suppes Brain Lab

Ventura Hall - CSLI

Stanford University

220 Panama street

Stanford CA 94305-4101

650 614 2305

650 630 5015 (cell)

marcospg@...

montereyunderwater@...

www.stanford.edu/~marcospg/

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The name Glivec actually has a very interesting story behind it.

When drug companies market drugs, they obviously have to assign names

to these drugs but it's a bit more complicated than that. The names

they pick, have to be pre-approved before they can be assigned to any

given drug and there are criteria to follow when they approve various

names. They don't just pick a name out of the sky and run with it,

there is an approval process to go through. Because of this process,

most drug companies have a list of drug names that have passed the

approval process but have not yet been officially assigned to a drug.

When Gleevec was in the first trials, it was only known as STI-571,

there was no brand name for it yet. They didn't know how successful

it was going to be or how fast it would be approved which meant that

they weren't prepared with a brand name for it.

As it turned out, it was approved in record time which meant that

they didn't have time to go through the process of finding a name for

it. Since approving names can take a while, they decided to use a

name that had already been approved for usage but wasn't yet assigned

to a drug.

The name Glivec was originally intended for a completely different

drug. It was supposed to be used for a drug that was made to treat

glioblastoma (a type of brain cancer) which explains the spelling.

Drug names are often similar to the conditions in which they treat.

Then from Glivec, as I originally mentioned, they came up with

Gleevec to make sure us North Americans would pronounce it properly.

Tracey

-- In , " Marcos Perreau Guimaraes "

<montereyunderwater@...> wrote:

>

> It is also glivec in France and most Europe. They must have learnt

as

> Tasigna (also by Novartis) has about the same pronunciation

> everywhere.

> Marcos.

>

> On Fri, Feb 22, 2008 at 5:56 PM, Tracey <traceyincanada@...> wrote:

> >

> >

> >

> >

> > As most drugs have a couple of names, it can get very confusing

when

> > trying to determine which are the same so here's a break down of

the

> > three most common drugs used for CML now:

> >

> > Gleevec is also called Glivec (in the UK) Imatinib, and STI571

> >

> > Sprycel is also called Dasatinib, and BMS-354825

> >

> > Tasigna is also called Nilotinib and AMN-107

> >

> > The first name is the brand name, the second name is the generic

name

> > and the third name is the name the drug was given in the first

trials

> > before it was approved.

> >

> > Gleevec is different than the rest because it actually has two

brand

> > names (Gleevec and Glivec). The reason is because Novartis was

> > worried that North American's wouldn't be able to pronounce it

> > properly if they called it Glivec so they changed the spelling to

be

> > more phonetically accurate.

> >

> > Tracey

> >

> >

>

>

>

> --

> Marcos Perreau Guimaraes

> Suppes Brain Lab

> Ventura Hall - CSLI

> Stanford University

> 220 Panama street

> Stanford CA 94305-4101

> 650 614 2305

> 650 630 5015 (cell)

> marcospg@...

> montereyunderwater@...

> www.stanford.edu/~marcospg/

>

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The precise etymology of the term Glivec is VECtor for GLIoblastoma, according

to Dr. Jurcic at MSKCC.

Carl

Marcos Perreau Guimaraes <montereyunderwater@...> wrote:

It is also glivec in France and most Europe. They must have learnt as

Tasigna (also by Novartis) has about the same pronunciation

everywhere.

Marcos.

On Fri, Feb 22, 2008 at 5:56 PM, Tracey <traceyincanada@...> wrote:

>

>

>

>

> As most drugs have a couple of names, it can get very confusing when

> trying to determine which are the same so here's a break down of the

> three most common drugs used for CML now:

>

> Gleevec is also called Glivec (in the UK) Imatinib, and STI571

>

> Sprycel is also called Dasatinib, and BMS-354825

>

> Tasigna is also called Nilotinib and AMN-107

>

> The first name is the brand name, the second name is the generic name

> and the third name is the name the drug was given in the first trials

> before it was approved.

>

> Gleevec is different than the rest because it actually has two brand

> names (Gleevec and Glivec). The reason is because Novartis was

> worried that North American's wouldn't be able to pronounce it

> properly if they called it Glivec so they changed the spelling to be

> more phonetically accurate.

>

> Tracey

>

>

--

Marcos Perreau Guimaraes

Suppes Brain Lab

Ventura Hall - CSLI

Stanford University

220 Panama street

Stanford CA 94305-4101

650 614 2305

650 630 5015 (cell)

marcospg@...

montereyunderwater@...

www.stanford.edu/~marcospg/

---------------------------------

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Thanks so much Tracey,

I spoke with what I thought was some authority and now know that both the person

I answered last night and I were right. I did not know that Tasagna was also

AMN 107 and Nilotinib.

I apologize to the man I ansered and to the rest of the group for promoting

incomplete knowledge of my subject. Will be more thorough and diligent from now

on.

I remember Tracey from years ago on the original list and definitely trust her

information.

L.

[ ] Drug names

As most drugs have a couple of names, it can get very confusing when

trying to determine which are the same so here's a break down of the

three most common drugs used for CML now:

Gleevec is also called Glivec (in the UK) Imatinib, and STI571

Sprycel is also called Dasatinib, and BMS-354825

Tasigna is also called Nilotinib and AMN-107

The first name is the brand name, the second name is the generic name

and the third name is the name the drug was given in the first trials

before it was approved.

Gleevec is different than the rest because it actually has two brand

names (Gleevec and Glivec). The reason is because Novartis was

worried that North American's wouldn't be able to pronounce it

properly if they called it Glivec so they changed the spelling to be

more phonetically accurate.

Tracey

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No harm done , I think we all get confused at one ponit or

another with these names.

Marcos.

On Sat, Feb 23, 2008 at 6:05 AM, seloew12 <seloew12@...> wrote:

>

>

>

>

> Thanks so much Tracey,

>

> I spoke with what I thought was some authority and now know that both the

> person I answered last night and I were right. I did not know that Tasagna

> was also AMN 107 and Nilotinib.

>

> I apologize to the man I ansered and to the rest of the group for promoting

> incomplete knowledge of my subject. Will be more thorough and diligent from

> now on.

>

> I remember Tracey from years ago on the original list and definitely trust

> her information.

>

> L.

>

> [ ] Drug names

>

> As most drugs have a couple of names, it can get very confusing when

> trying to determine which are the same so here's a break down of the

> three most common drugs used for CML now:

>

> Gleevec is also called Glivec (in the UK) Imatinib, and STI571

>

> Sprycel is also called Dasatinib, and BMS-354825

>

> Tasigna is also called Nilotinib and AMN-107

>

> The first name is the brand name, the second name is the generic name

> and the third name is the name the drug was given in the first trials

> before it was approved.

>

> Gleevec is different than the rest because it actually has two brand

> names (Gleevec and Glivec). The reason is because Novartis was

> worried that North American's wouldn't be able to pronounce it

> properly if they called it Glivec so they changed the spelling to be

> more phonetically accurate.

>

> Tracey

>

>

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Thanks Marcos,

I felt bad about that. I used to have much of the cml news but with all the

advances in science haven't kept up as I should.

Cheers,

L

[ ] Drug names

>

> As most drugs have a couple of names, it can get very confusing when

> trying to determine which are the same so here's a break down of the

> three most common drugs used for CML now:

>

> Gleevec is also called Glivec (in the UK) Imatinib, and STI571

>

> Sprycel is also called Dasatinib, and BMS-354825

>

> Tasigna is also called Nilotinib and AMN-107

>

> The first name is the brand name, the second name is the generic name

> and the third name is the name the drug was given in the first trials

> before it was approved.

>

> Gleevec is different than the rest because it actually has two brand

> names (Gleevec and Glivec). The reason is because Novartis was

> worried that North American's wouldn't be able to pronounce it

> properly if they called it Glivec so they changed the spelling to be

> more phonetically accurate.

>

> Tracey

>

>

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Yes, I too felt anxious and scared about situations that did

not give me another thought before Gleevec. I tried Ativan,

but it really did not take the feeling away.

Finally I dropped all medications with the exception of

Gleevec and noted the interactions they may have caused,

certainly could have included feelings of panic or uneasiness

or something. For me it ended up being Gleevec and Compazine

(or its generic equivalent). Once I no longer took Compazine

my anxiousness and fear went away.

Just me two cents.

Matt

ville, Fl

Survivor since 2005

**************Ideas to please picky eaters. Watch video on AOL Living.

(http://living.aol.com/video/how-to-please-your-picky-eater/rachel-campos-duffy/

2050827?NCID=aolcmp00300000002598)

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My 80 year old grandmother (diagnosed with CML, Oct. 2007) has been on Gleevec

for a little over a year now and I know I have read about some of you getting

real tired and your memory not being so good on Gleevec, but is anyone

experiencing nervousness? Here lately she physically shakes and today she said

that she felt scared. She has been put on a low dose of Tranzene. It just

doesn't seem to work. Help!!!

[ ] Drug names

>

> As most drugs have a couple of names, it can get very confusing when

> trying to determine which are the same so here's a break down of the

> three most common drugs used for CML now:

>

> Gleevec is also called Glivec (in the UK) Imatinib, and STI571

>

> Sprycel is also called Dasatinib, and BMS-354825

>

> Tasigna is also called Nilotinib and AMN-107

>

> The first name is the brand name, the second name is the generic name

> and the third name is the name the drug was given in the first trials

> before it was approved.

>

> Gleevec is different than the rest because it actually has two brand

> names (Gleevec and Glivec). The reason is because Novartis was

> worried that North American's wouldn't be able to pronounce it

> properly if they called it Glivec so they changed the spelling to be

> more phonetically accurate.

>

> Tracey

>

>

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Kristie,

Yes, of course there's some panic among us because for all the new meds

available to us, cml remains a life-threatening disease and we endure needle

after needle, meds that may have profound side effects plus having heard all our

lives until recent years that leukemia was a death sentence. It no longer is.

So, I have shaken with fear, with fevers and cold and sometimes just because my

diet needed something it didn't have.

Your grandmother can still be considered as newly diagnosed so she's on a new

path which she didn't choose. Perhaps other people here in the group know her

story but I don't. She could even have some sugar imabalance.

If her oncologist is not a cml speciaist -- and most are not -- then I suggest

you find one if at all possible. Also, there is another site I would recommend

in addition to this one where there are other people who have CML and the

discussion is helpful. It is www.newcmldrug.com.

All the best to you and your grandmother.

L.

[ ] Drug names

>

> As most drugs have a couple of names, it can get very confusing when

> trying to determine which are the same so here's a break down of the

> three most common drugs used for CML now:

>

> Gleevec is also called Glivec (in the UK) Imatinib, and STI571

>

> Sprycel is also called Dasatinib, and BMS-354825

>

> Tasigna is also called Nilotinib and AMN-107

>

> The first name is the brand name, the second name is the generic name

> and the third name is the name the drug was given in the first trials

> before it was approved.

>

> Gleevec is different than the rest because it actually has two brand

> names (Gleevec and Glivec). The reason is because Novartis was

> worried that North American's wouldn't be able to pronounce it

> properly if they called it Glivec so they changed the spelling to be

> more phonetically accurate.

>

> Tracey

>

>

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