Guest guest Posted January 12, 2008 Report Share Posted January 12, 2008 The number of bcr-abl copies was divided by 38 in two months. Aka for every 100 cml cells in October, only about 2 and a half are still there in December. Whatever the log reduction from baseline was in October, it was improved by about 1.6 from then to December. The baseline or the log reduction are not mentioned so I dunno for the current log reduction from the lab's baseline, aka the number that is used to determine if he is in major molecular remission (mmr = -3 log). That does sound like pretty good anyway Marcos On Jan 12, 2008 2:36 PM, Cervera <weez_555@...> wrote: > > > > > > Hi guys-- > 's doc just sent an email with the below message in it. > Can someone please interpret for us? > > We understand that it did go down, thus an improvement (which is all we > actually really care about at this point).. > > Any interpretation as to what degree the drop is, would be nice to know! > > Hi , > Your PCR results form bone marrow 12/19/07: > Positive at 1.1 X 10-4; this is reduced c/w prior value 4.2 X 10-3 from > 10/17/07. > I interpret this as positive; continued regression of the CML clone. > > (chromosomes negative-20 cells, FISH negative-250 cells) > > See you soon, email or call if you have questions. > ELIZABETH D SIMMONS MD > > Thanks! > > > __________________________________________________________ > Share life as it happens with the new Windows Live. > http://www.windowslive.com/share.html?ocid=TXT_TAGHM_Wave2_sharelife_012008 > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 12, 2008 Report Share Posted January 12, 2008 > > > Hi guys-- > 's doc just sent an email with the below message in it. > Can someone please interpret for us? > > We understand that it did go down, thus an improvement (which is all we actually really care about at this point).. > > Any interpretation as to what degree the drop is, would be nice to know! > > Hi , > Your PCR results form bone marrow 12/19/07: > Positive at 1.1 X 10-4; this is reduced c/w prior value 4.2 X 10-3 from 10/17/07. The result is in scientific notation. To conver to a whole number, put some zeros to the left of the 1.1. Its to the left since x10 is a minus number. (Zeros to the right after the 1.1 if the x10 number was positive). Then skip the decimal to the left placing between a zero and do this the number of times the shown in the x10. In this case 4 skips. It would look like 0.00011 when done. This is the whole number. To get it a percentage, back the decimal to places to the right. This gives a result of 0.011%. It depends on the lab but this is at a point that many consider as reaching or very close to a Major Molecular Response. Congratulations. Quote Link to comment Share on other sites More sharing options...
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