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I have to agree with all respondents! I wonder how up on current CML

options he really is? There are so many other than BMT options out there that

I am

shocked he is so insistent. I am 42, diagnosed exactly one year ago today,

01 March 2007. My Onc has maintained the BMT when all other options are

exhausted. He stated, and I personally agree that so long as the patient is

responding to meds, why risk the mortality rate of a BMT? I 100% agree, at

least

for me. I also would urge you to see a CML guru - specialist like Dr

Druker, before going the BMT route. Perhaps your Onc sees something more than

stated and is not sharing. My extended family had been urging me to have them

type matched, to see if any are matches. I will soon, but have put it off a

little, as I seriously do not plan to go the BMT route, God willing.

Cheers,

Chris

**************Ideas to please picky eaters. Watch video on AOL Living.

(http://living.aol.com/video/how-to-please-your-picky-eater/rachel-campos-duffy/

2050827?NCID=aolcmp00300000002598)

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I saw new oncologist/hematologist... he seems very up.. He did his

fellowship at Stanford etc. Anyway, I was quite suprised when he told

me I had possibly 10 good years with the medications and that

eventuality would be tolerance to the medications by CML and eventual

progression. I'm 35 and he said I would not approach the 30 to 40

years I had left on this earth with everything that was currently

available. He then went on to say that BMT is the best option for

someone my age and it was best done in the next year or two too

increase odds of surviving CML free. I have 4 eligible siblings and 2

children (too young to be tested I think.) So, he's telling me I need

BMT after I figure how to get some type of ins coverage. He would

like to see that happen in the next year if possible. Sigh. I

generally agree but little overwhelmed. Who else is my age and what

have you been told. I have a lot of problems tolerating Sprycel. I

was very SOB yesterday. Got Chest xray and wait to see if there's

some fluid. Anyway, looking for your advice.. on how to get through

this and where the heck to begin etc. I've read some stuff about BMT,

so I have some knowledge etc, I think the logistics is going to kill

me. I live in REno. They reccommend going to Seattle or LA (City of

Hope). I've been to Stanford... They said that would be OK too.

Family in VEgas. Friend in Seattle with twin babies. A friend has mom

who lives near STanford. I have two kids, 7 and 2 years (girls). My

husband is a sub teacher and on verge of getting contract and

possibly insurance but pre existing.... would be 15 to 18 months I

think before anything was covered (3 month eligiblity period included

and wouldn't start until very late August. Suggestions... Advice...

What do you all think?

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Hi,

I love the responses.

My question to your doctor is on what data does he base his prediction on.

Did he also explain the survival rates when it comes to a BMT?

My advice to you is to get a consult with one of the CML biggies and get

their opinion on what to do.

Zavie

Zavie (age 69)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.2 log reduction Jun/07

3.6 log reduction Sep/07

3.5 log reduction Feb/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of

marri35

Sent: March 1, 2008 11:23 PM

Subject: [ ] Re: BMT

THanks... that was helpful.

> he told

> > me I had possibly 10 good years with the medications and that

> > eventuality would be tolerance to the medications by CML and

eventual

> > progression. ........................ Suggestions... Advice...

> > What do you all think?

>

>

> ***************************************

>

> My suggestion is to have him tell you the lottery numbers for the

next

> draw since he seems to have such a firm grasp on the future!

>

> Tracey

>

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He had no right telling you that. You are young, strong and you do not know

what the future holds for us. I am 65 and have had CML for 4 years. Been

through gleevec, and just off Sprycel .now going to Tasigna. I am PCRU but

the side effects are bad for me. But there are others that are doing very

very very well. And if I get bad side effects on Tasigna I will go back to

Sprycel. I did wonderfully for three years on it. And by then there will be

something else. Do not give up.

Sharon

_____

From: [mailto: ] On Behalf Of Tracey

Sent: Saturday, March 01, 2008 7:24 PM

Subject: [ ] Re: BMT

he told

> me I had possibly 10 good years with the medications and that

> eventuality would be tolerance to the medications by CML and eventual

> progression. ........................ Suggestions... Advice...

> What do you all think?

***************************************

My suggestion is to have him tell you the lottery numbers for the next

draw since he seems to have such a firm grasp on the future!

Tracey

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I guess I have the next year to figure this out. I have done terribly

on Sprycel. I hope that I have responded too it cytogenically or

whatever. This is cotor explained it: He said since I was 35 that

gave me potentially 30 to 40 years in front of me. He said it was

likely CML would get me in the end before I reached that 30 to 40

years even with medications available now. I think he is telling me

that BMT is still the best way to cure and I am young enough to

tolerate it. I'm confused at best but I know I wouldn't mind the

prospect of not being on Sprycel or other medication if that were

possible. He also alluded to toxicity after time with the meds. So,

where's Dr. Druker at... does someone have an email for him. I

certainly would love to have a second opinion. I don't know what to

do. I don't know why I feel incredibly crappy on medicine. I feel

better when I miss a day but I'm trying to keep on track. I tell

myself it will settle down. Thanks everyone for your input.

> > he told

> > > me I had possibly 10 good years with the medications and that

> > > eventuality would be tolerance to the medications by CML and

eventual

> > > progression. ........................ Suggestions... Advice...

> > > What do you all think?

> >

> > ***************************************

> >

> > My suggestion is to have him tell you the lottery numbers for the

next

> > draw since he seems to have such a firm grasp on the future!

> >

> > Tracey

> >

> >

> >

> >

>

>

>

> --

> Marcos Perreau Guimaraes

> Suppes Brain Lab

> Ventura Hall - CSLI

> Stanford University

> 220 Panama street

> Stanford CA 94305-4101

> 650 614 2305

> 650 630 5015 (cell)

> marcospg@...

> montereyunderwater@...

> www.stanford.edu/~marcospg/

>

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Hi Marrianne,

Dr. Druker's coordinates:

Dr. Druker

Oregon Health Sciences University

Division of Hematology & Medical Oncology, L592

3181 Southwest Sam Park Road

Portland, Oregon, 97201-3098

USA

503-494-5596

503-494-3688 FAX

drukerb@...

There are several other medications that work where Gleevec and Sprycel

don't. Dr. Druker will be the best person to explain your options.

Zavie

Zavie (age 69)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.2 log reduction Jun/07

3.6 log reduction Sep/07

3.5 log reduction Feb/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of

marri35

Sent: March 2, 2008 12:22 PM

Subject: [ ] Re: BMT

I guess I have the next year to figure this out. I have done terribly

on Sprycel. I hope that I have responded too it cytogenically or

whatever. This is cotor explained it: He said since I was 35 that

gave me potentially 30 to 40 years in front of me. He said it was

likely CML would get me in the end before I reached that 30 to 40

years even with medications available now. I think he is telling me

that BMT is still the best way to cure and I am young enough to

tolerate it. I'm confused at best but I know I wouldn't mind the

prospect of not being on Sprycel or other medication if that were

possible. He also alluded to toxicity after time with the meds. So,

where's Dr. Druker at... does someone have an email for him. I

certainly would love to have a second opinion. I don't know what to

do. I don't know why I feel incredibly crappy on medicine. I feel

better when I miss a day but I'm trying to keep on track. I tell

myself it will settle down. Thanks everyone for your input.

> > he told

> > > me I had possibly 10 good years with the medications and that

> > > eventuality would be tolerance to the medications by CML and

eventual

> > > progression. ........................ Suggestions... Advice...

> > > What do you all think?

> >

> > ***************************************

> >

> > My suggestion is to have him tell you the lottery numbers for the

next

> > draw since he seems to have such a firm grasp on the future!

> >

> > Tracey

> >

> >

> >

> >

>

>

>

> --

> Marcos Perreau Guimaraes

> Suppes Brain Lab

> Ventura Hall - CSLI

> Stanford University

> 220 Panama street

> Stanford CA 94305-4101

> 650 614 2305

> 650 630 5015 (cell)

> marcospg@...

> montereyunderwater@...

> www.stanford.edu/~marcospg/

>

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Guest guest

The main thing to keep in mind is if you are responding to Sprycel you

have time to decide. I was diagnosed at 38 (41 now) and had somewhat a

comparable experience with my hematologist at Kaiser. Although he

wasn't as pushy as you describe your dr he did lean at first towards a

BMT, I was in very good physical shape, but I strongly resisted, and a

2nd opinion from a cml specialist in Paris confirmed that a BMT was

not anymore a sensible first option, even at 38. Now they even

hesitate proposing tthat to kids with cml.

The drug (gleevec for me) was a little rough for the first month but

it got a lot better and now I am in pretty good shape, working,

climbing, diving. The most important thing is the test results

(cytogenetics, FISH and PCR), if you have a good response the 1st year

(reach complete cytogenetic remission, or better, major molecular

remission) you will be pretty much out of the wood. If you don't get

used to Sprycel you have other options such as Tasigna. If you have

problems with the cost of the drugs others, on the list have

experience getting them at low cost or free from the labs. I have good

benefits from my job at Stanford so I never ran into the problem. If

you go to Stanford and want to chat with a fellow cmler over coffee I

d be happy to, I work across the street from the hospital.

Marcos.

On Sun, Mar 2, 2008 at 9:21 AM, marri35 <tmtip@...> wrote:

>

>

>

>

> I guess I have the next year to figure this out. I have done terribly

> on Sprycel. I hope that I have responded too it cytogenically or

> whatever. This is cotor explained it: He said since I was 35 that

> gave me potentially 30 to 40 years in front of me. He said it was

> likely CML would get me in the end before I reached that 30 to 40

> years even with medications available now. I think he is telling me

> that BMT is still the best way to cure and I am young enough to

> tolerate it. I'm confused at best but I know I wouldn't mind the

> prospect of not being on Sprycel or other medication if that were

> possible. He also alluded to toxicity after time with the meds. So,

> where's Dr. Druker at... does someone have an email for him. I

> certainly would love to have a second opinion. I don't know what to

> do. I don't know why I feel incredibly crappy on medicine. I feel

> better when I miss a day but I'm trying to keep on track. I tell

> myself it will settle down. Thanks everyone for your input.

>

>

> > > he told

> > > > me I had possibly 10 good years with the medications and that

> > > > eventuality would be tolerance to the medications by CML and

> eventual

> > > > progression. ........................ Suggestions... Advice...

> > > > What do you all think?

> > >

> > > ***************************************

> > >

> > > My suggestion is to have him tell you the lottery numbers for the

> next

> > > draw since he seems to have such a firm grasp on the future!

> > >

> > > Tracey

> > >

> > >

> > >

> > >

> >

> >

> >

> > --

> > Marcos Perreau Guimaraes

> > Suppes Brain Lab

> > Ventura Hall - CSLI

> > Stanford University

> > 220 Panama street

> > Stanford CA 94305-4101

> > 650 614 2305

> > 650 630 5015 (cell)

> > marcospg@...

> > montereyunderwater@...

> > www.stanford.edu/~marcospg/

> >

>

>

>

>

--

Marcos Perreau Guimaraes

Suppes Brain Lab

Ventura Hall - CSLI

Stanford University

220 Panama street

Stanford CA 94305-4101

650 614 2305

650 630 5015 (cell)

marcospg@...

montereyunderwater@...

www.stanford.edu/~marcospg/

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  • 3 weeks later...
Guest guest

Marri35:

I know this is a late response, I am clearing old e-mail out today. I had CML,

was dx in April 2005. Started on Gleevec and became resistant to it in 06. Did

a short stint on Sprycel to hold me to transplant. It has been 13 months since

transplant. I had a Mini Mud. I do not know my donor.

Since having done the chemo and transplant I am in remission for CML. I have

been since a couple of months after the transplant. It took almost a year for

the new cells to come in and I have a new immune system. When I did the

transplant I was 48 years old, young compared to the others in my transplant

group. Because I do not have CML any longer I do not take the Gleevec or the

Sprycel to maintain. My diseased cells are gone, I now have healthy cells.

It took almost a year for me to get back to work. I won't say the transplant is

easy. There is no easy path out of our situation. If you choose transplant

there will be other issues. I have had minor gVHD, and a lung infection. But

I am free of the CML. The issues are being worked out, CML would have killed

me.

First, get your insurance issues in order. Then you have to weigh out how you

feel about your direction. You will need a caregiver for at least 4-5 months.

You will be sick. But then your health will start coming back. Do not let

scare tactics from people that have not gone through this procedure weigh in

your decisions. Even if you don't want to go to transplant you may have to due

to the drugs not working. Get you donor situation in order.

I have spent the last year fighting for my life. I am glad to no longer be

fighting the medication battle with CML. I have a chance to get my life back.

Yeah, there are hurdles along the way. Don't tell me you live with CML and it

is all smooth. I was told this month that if all goes well in the next few

months I will be living with out restrictions and disease free for the first

time in years. I am glad I took the chance with transplant. I might just get

to see my youngest daughter graduate from college after all! Best of luck with

you decisions. Oh also,. don't go to Stanford to do this procedure. Hutch in

Seattle is one of the best facilities in the country to transplant. Mine was

done in Atlanta so I could stay close to my daughters. It has gone ok, make

your own decision based on your life and not fear.

Best Regards,

Therese Stone

marri35 <tmtip@...> wrote: I saw new

oncologist/hematologist... he seems very up.. He did his

fellowship at Stanford etc. Anyway, I was quite suprised when he told

me I had possibly 10 good years with the medications and that

eventuality would be tolerance to the medications by CML and eventual

progression. I'm 35 and he said I would not approach the 30 to 40

years I had left on this earth with everything that was currently

available. He then went on to say that BMT is the best option for

someone my age and it was best done in the next year or two too

increase odds of surviving CML free. I have 4 eligible siblings and 2

children (too young to be tested I think.) So, he's telling me I need

BMT after I figure how to get some type of ins coverage. He would

like to see that happen in the next year if possible. Sigh. I

generally agree but little overwhelmed. Who else is my age and what

have you been told. I have a lot of problems tolerating Sprycel. I

was very SOB yesterday. Got Chest xray and wait to see if there's

some fluid. Anyway, looking for your advice.. on how to get through

this and where the heck to begin etc. I've read some stuff about BMT,

so I have some knowledge etc, I think the logistics is going to kill

me. I live in REno. They reccommend going to Seattle or LA (City of

Hope). I've been to Stanford... They said that would be OK too.

Family in VEgas. Friend in Seattle with twin babies. A friend has mom

who lives near STanford. I have two kids, 7 and 2 years (girls). My

husband is a sub teacher and on verge of getting contract and

possibly insurance but pre existing.... would be 15 to 18 months I

think before anything was covered (3 month eligiblity period included

and wouldn't start until very late August. Suggestions... Advice...

What do you all think?

---------------------------------

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Marri35:

One more thing, I don't see choosing a transplant as giving up on life. It

actually give you one more option to choosing life. Transplant has been done

for many, many years. Once you start looking into this option you will see how

advanced this medical has become. Don't be archaic with the stats you look at,

be up to date. Good Luck.

Therese Stone

marri35 <tmtip@...> wrote: I saw new

oncologist/hematologist... he seems very up.. He did his

fellowship at Stanford etc. Anyway, I was quite suprised when he told

me I had possibly 10 good years with the medications and that

eventuality would be tolerance to the medications by CML and eventual

progression. I'm 35 and he said I would not approach the 30 to 40

years I had left on this earth with everything that was currently

available. He then went on to say that BMT is the best option for

someone my age and it was best done in the next year or two too

increase odds of surviving CML free. I have 4 eligible siblings and 2

children (too young to be tested I think.) So, he's telling me I need

BMT after I figure how to get some type of ins coverage. He would

like to see that happen in the next year if possible. Sigh. I

generally agree but little overwhelmed. Who else is my age and what

have you been told. I have a lot of problems tolerating Sprycel. I

was very SOB yesterday. Got Chest xray and wait to see if there's

some fluid. Anyway, looking for your advice.. on how to get through

this and where the heck to begin etc. I've read some stuff about BMT,

so I have some knowledge etc, I think the logistics is going to kill

me. I live in REno. They reccommend going to Seattle or LA (City of

Hope). I've been to Stanford... They said that would be OK too.

Family in VEgas. Friend in Seattle with twin babies. A friend has mom

who lives near STanford. I have two kids, 7 and 2 years (girls). My

husband is a sub teacher and on verge of getting contract and

possibly insurance but pre existing.... would be 15 to 18 months I

think before anything was covered (3 month eligiblity period included

and wouldn't start until very late August. Suggestions... Advice...

What do you all think?

---------------------------------

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Guest guest

Hello Marri, I never post to anyone who is considering transplant, as it is not

an option for me, at 78, so I have no knowledge of it. But if you have not had

a second opinion on this, may I suggest that you get one? Dr. Druker in

Portland Oregon and Dr. Talpaz in Ann Arbor, are to me the two finest doctors in

the states. I have had cml for 13 years, and they only gave me 5 years in 1995,

and I'm still around and kicking! And that is because of all the new drugs, and

there are more in the near future. Good luck with your decision, I know it is

not an easy one. Blessings, Bobby

Therese Stone <kidme2003@...> wrote: Marri35:

One more thing, I don't see choosing a transplant as giving up on life. It

actually give you one more option to choosing life. Transplant has been done for

many, many years. Once you start looking into this option you will see how

advanced this medical has become. Don't be archaic with the stats you look at,

be up to date. Good Luck.

Therese Stone

marri35 <tmtip@...> wrote: I saw new oncologist/hematologist... he

seems very up.. He did his

fellowship at Stanford etc. Anyway, I was quite suprised when he told

me I had possibly 10 good years with the medications and that

eventuality would be tolerance to the medications by CML and eventual

progression. I'm 35 and he said I would not approach the 30 to 40

years I had left on this earth with everything that was currently

available. He then went on to say that BMT is the best option for

someone my age and it was best done in the next year or two too

increase odds of surviving CML free. I have 4 eligible siblings and 2

children (too young to be tested I think.) So, he's telling me I need

BMT after I figure how to get some type of ins coverage. He would

like to see that happen in the next year if possible. Sigh. I

generally agree but little overwhelmed. Who else is my age and what

have you been told. I have a lot of problems tolerating Sprycel. I

was very SOB yesterday. Got Chest xray and wait to see if there's

some fluid. Anyway, looking for your advice.. on how to get through

this and where the heck to begin etc. I've read some stuff about BMT,

so I have some knowledge etc, I think the logistics is going to kill

me. I live in REno. They reccommend going to Seattle or LA (City of

Hope). I've been to Stanford... They said that would be OK too.

Family in VEgas. Friend in Seattle with twin babies. A friend has mom

who lives near STanford. I have two kids, 7 and 2 years (girls). My

husband is a sub teacher and on verge of getting contract and

possibly insurance but pre existing.... would be 15 to 18 months I

think before anything was covered (3 month eligiblity period included

and wouldn't start until very late August. Suggestions... Advice...

What do you all think?

---------------------------------

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Guest guest

I second Zavie. This is not about scare tactics or choosing sides in a

football game. BMT is just not anymore the front line treatment of

cml. No cml specialists advise it for chronic phase patients without

trying the drugs first, neither LLS, NCF or European cancer

organisations. Survival and remission rates for newly dx patients are

a lot better with gleevec alone. If the drugs fail then BMT becomes

one of the options. Anyway nobody should take this kind of decision

without getting the opinion of one of the leader cml specialists. CML

is a rare form of leukemia and most hematologists/oncologists don't

see enough cml patients to be knowledgeable about current options. I

am glad the BMT worked for you Theresa, and that you overcame the loss

of remission with gleevec. And you are right that BMTs are getting

better, but we don't even know if Marry is responding to the drug. And

there is also no reason to rush a decision one way or another.

Marcos.

On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE <rcd1929@...> wrote:

>

>

>

>

> Hello Marri, I never post to anyone who is considering transplant, as it is

> not an option for me, at 78, so I have no knowledge of it. But if you have

> not had a second opinion on this, may I suggest that you get one? Dr. Druker

> in Portland Oregon and Dr. Talpaz in Ann Arbor, are to me the two finest

> doctors in the states. I have had cml for 13 years, and they only gave me 5

> years in 1995, and I'm still around and kicking! And that is because of all

> the new drugs, and there are more in the near future. Good luck with your

> decision, I know it is not an easy one. Blessings, Bobby

>

> Therese Stone <kidme2003@...> wrote: Marri35:

>

>

>

> One more thing, I don't see choosing a transplant as giving up on life. It

> actually give you one more option to choosing life. Transplant has been done

> for many, many years. Once you start looking into this option you will see

> how advanced this medical has become. Don't be archaic with the stats you

> look at, be up to date. Good Luck.

>

> Therese Stone

>

> marri35 <tmtip@...> wrote: I saw new oncologist/hematologist... he

> seems very up.. He did his

> fellowship at Stanford etc. Anyway, I was quite suprised when he told

> me I had possibly 10 good years with the medications and that

> eventuality would be tolerance to the medications by CML and eventual

> progression. I'm 35 and he said I would not approach the 30 to 40

> years I had left on this earth with everything that was currently

> available. He then went on to say that BMT is the best option for

> someone my age and it was best done in the next year or two too

> increase odds of surviving CML free. I have 4 eligible siblings and 2

> children (too young to be tested I think.) So, he's telling me I need

> BMT after I figure how to get some type of ins coverage. He would

> like to see that happen in the next year if possible. Sigh. I

> generally agree but little overwhelmed. Who else is my age and what

> have you been told. I have a lot of problems tolerating Sprycel. I

> was very SOB yesterday. Got Chest xray and wait to see if there's

> some fluid. Anyway, looking for your advice.. on how to get through

> this and where the heck to begin etc. I've read some stuff about BMT,

> so I have some knowledge etc, I think the logistics is going to kill

> me. I live in REno. They reccommend going to Seattle or LA (City of

> Hope). I've been to Stanford... They said that would be OK too.

> Family in VEgas. Friend in Seattle with twin babies. A friend has mom

> who lives near STanford. I have two kids, 7 and 2 years (girls). My

> husband is a sub teacher and on verge of getting contract and

> possibly insurance but pre existing.... would be 15 to 18 months I

> think before anything was covered (3 month eligiblity period included

> and wouldn't start until very late August. Suggestions... Advice...

> What do you all think?

>

> ---------------------------------

> Looking for last minute shopping deals? Find them fast with Search.

>

>

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Guest guest

Ooops, I second a. The concatenation of adresses and signatures

got me confused, sorry a :)

Marcos.

On Sun, Mar 23, 2008 at 12:06 PM, Marcos Perreau Guimaraes

<montereyunderwater@...> wrote:

> I second Zavie. This is not about scare tactics or choosing sides in a

> football game. BMT is just not anymore the front line treatment of

> cml. No cml specialists advise it for chronic phase patients without

> trying the drugs first, neither LLS, NCF or European cancer

> organisations. Survival and remission rates for newly dx patients are

> a lot better with gleevec alone. If the drugs fail then BMT becomes

> one of the options. Anyway nobody should take this kind of decision

> without getting the opinion of one of the leader cml specialists. CML

> is a rare form of leukemia and most hematologists/oncologists don't

> see enough cml patients to be knowledgeable about current options. I

> am glad the BMT worked for you Theresa, and that you overcame the loss

> of remission with gleevec. And you are right that BMTs are getting

> better, but we don't even know if Marry is responding to the drug. And

> there is also no reason to rush a decision one way or another.

> Marcos.

>

>

> On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE <rcd1929@...> wrote:

> >

> >

> >

> >

> > Hello Marri, I never post to anyone who is considering transplant, as it is

> > not an option for me, at 78, so I have no knowledge of it. But if you have

> > not had a second opinion on this, may I suggest that you get one? Dr. Druker

> > in Portland Oregon and Dr. Talpaz in Ann Arbor, are to me the two finest

> > doctors in the states. I have had cml for 13 years, and they only gave me 5

> > years in 1995, and I'm still around and kicking! And that is because of all

> > the new drugs, and there are more in the near future. Good luck with your

> > decision, I know it is not an easy one. Blessings, Bobby

> >

> > Therese Stone <kidme2003@...> wrote: Marri35:

> >

> >

> >

> > One more thing, I don't see choosing a transplant as giving up on life. It

> > actually give you one more option to choosing life. Transplant has been done

> > for many, many years. Once you start looking into this option you will see

> > how advanced this medical has become. Don't be archaic with the stats you

> > look at, be up to date. Good Luck.

> >

> > Therese Stone

> >

> > marri35 <tmtip@...> wrote: I saw new oncologist/hematologist... he

> > seems very up.. He did his

> > fellowship at Stanford etc. Anyway, I was quite suprised when he told

> > me I had possibly 10 good years with the medications and that

> > eventuality would be tolerance to the medications by CML and eventual

> > progression. I'm 35 and he said I would not approach the 30 to 40

> > years I had left on this earth with everything that was currently

> > available. He then went on to say that BMT is the best option for

> > someone my age and it was best done in the next year or two too

> > increase odds of surviving CML free. I have 4 eligible siblings and 2

> > children (too young to be tested I think.) So, he's telling me I need

> > BMT after I figure how to get some type of ins coverage. He would

> > like to see that happen in the next year if possible. Sigh. I

> > generally agree but little overwhelmed. Who else is my age and what

> > have you been told. I have a lot of problems tolerating Sprycel. I

> > was very SOB yesterday. Got Chest xray and wait to see if there's

> > some fluid. Anyway, looking for your advice.. on how to get through

> > this and where the heck to begin etc. I've read some stuff about BMT,

> > so I have some knowledge etc, I think the logistics is going to kill

> > me. I live in REno. They reccommend going to Seattle or LA (City of

> > Hope). I've been to Stanford... They said that would be OK too.

> > Family in VEgas. Friend in Seattle with twin babies. A friend has mom

> > who lives near STanford. I have two kids, 7 and 2 years (girls). My

> > husband is a sub teacher and on verge of getting contract and

> > possibly insurance but pre existing.... would be 15 to 18 months I

> > think before anything was covered (3 month eligiblity period included

> > and wouldn't start until very late August. Suggestions... Advice...

> > What do you all think?

> >

> > ---------------------------------

> > Looking for last minute shopping deals? Find them fast with Search.

> >

> >

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Guest guest

Hey Marcos:

It takes a tremendous amount of planning and dx to make any decision regarding

your medical care. I do not consider what any one of us are going through " a

game " . I am giving my opinion on my experiences with my treatment of CML.

I payed my dues to all of this and have experience to share with those that

might be backed into the corner I was in. As far as treatment for the CML my

options were getting very limited. I decided not to wait to blast crisis before

the latest and greatest trial came along. I needed to take action. My CML was

past wait and see stage.

The doctors I see all agreed it was time to consider a transplant. After 14

months of transplant recovery, I think it was a good choice. Any treatment we

choose should be planned out very carefully. If you choose drugs or transplant

you need a course of action. Financially, emotionally, mentally, insurance,

if needed - donors, all need careful planning to survive the treatment.

I am pissed you think I feel this is a game, let me tell you something, I fought

hard to keep my life. We are warriors fighting a battle. Hope we all come out

on the winning end.

Therese

Marcos Perreau Guimaraes <montereyunderwater@...> wrote:

I second Zavie. This is not about scare tactics or choosing sides in a

football game. BMT is just not anymore the front line treatment of

cml. No cml specialists advise it for chronic phase patients without

trying the drugs first, neither LLS, NCF or European cancer

organisations. Survival and remission rates for newly dx patients are

a lot better with gleevec alone. If the drugs fail then BMT becomes

one of the options. Anyway nobody should take this kind of decision

without getting the opinion of one of the leader cml specialists. CML

is a rare form of leukemia and most hematologists/oncologists don't

see enough cml patients to be knowledgeable about current options. I

am glad the BMT worked for you Theresa, and that you overcame the loss

of remission with gleevec. And you are right that BMTs are getting

better, but we don't even know if Marry is responding to the drug. And

there is also no reason to rush a decision one way or another.

Marcos.

On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE <rcd1929@...> wrote:

>

>

>

>

> Hello Marri, I never post to anyone who is considering transplant, as it is

> not an option for me, at 78, so I have no knowledge of it. But if you have

> not had a second opinion on this, may I suggest that you get one? Dr. Druker

> in Portland Oregon and Dr. Talpaz in Ann Arbor, are to me the two finest

> doctors in the states. I have had cml for 13 years, and they only gave me 5

> years in 1995, and I'm still around and kicking! And that is because of all

> the new drugs, and there are more in the near future. Good luck with your

> decision, I know it is not an easy one. Blessings, Bobby

>

> Therese Stone <kidme2003@...> wrote: Marri35:

>

>

>

> One more thing, I don't see choosing a transplant as giving up on life. It

> actually give you one more option to choosing life. Transplant has been done

> for many, many years. Once you start looking into this option you will see

> how advanced this medical has become. Don't be archaic with the stats you

> look at, be up to date. Good Luck.

>

> Therese Stone

>

> marri35 <tmtip@...> wrote: I saw new oncologist/hematologist... he

> seems very up.. He did his

> fellowship at Stanford etc. Anyway, I was quite suprised when he told

> me I had possibly 10 good years with the medications and that

> eventuality would be tolerance to the medications by CML and eventual

> progression. I'm 35 and he said I would not approach the 30 to 40

> years I had left on this earth with everything that was currently

> available. He then went on to say that BMT is the best option for

> someone my age and it was best done in the next year or two too

> increase odds of surviving CML free. I have 4 eligible siblings and 2

> children (too young to be tested I think.) So, he's telling me I need

> BMT after I figure how to get some type of ins coverage. He would

> like to see that happen in the next year if possible. Sigh. I

> generally agree but little overwhelmed. Who else is my age and what

> have you been told. I have a lot of problems tolerating Sprycel. I

> was very SOB yesterday. Got Chest xray and wait to see if there's

> some fluid. Anyway, looking for your advice.. on how to get through

> this and where the heck to begin etc. I've read some stuff about BMT,

> so I have some knowledge etc, I think the logistics is going to kill

> me. I live in REno. They reccommend going to Seattle or LA (City of

> Hope). I've been to Stanford... They said that would be OK too.

> Family in VEgas. Friend in Seattle with twin babies. A friend has mom

> who lives near STanford. I have two kids, 7 and 2 years (girls). My

> husband is a sub teacher and on verge of getting contract and

> possibly insurance but pre existing.... would be 15 to 18 months I

> think before anything was covered (3 month eligiblity period included

> and wouldn't start until very late August. Suggestions... Advice...

> What do you all think?

>

> ---------------------------------

> Looking for last minute shopping deals? Find them fast with Search.

>

>

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Guest guest

Hi Therese,

I wasn't thinking you chose a BMT without reasons, you mentioned

gleevec stopped working and I can understand you had some tough

decisions to make, and BMT was certainly a sensible option at that

point, I am sincerely glad you did well with it and I can only imagine

you had some really rough time and lot of courage to pull through. I

never suggested you take it as a game, sorry if it sounded that way,

it was just about taking sides, and we sometime tend to take sides

even when it is not a game. Well, before being a cml warrior, I have

been a soldier, I guess I did that too :). My point was that the ones

who talked about other options weren't just trying to scare marry just

because we don't like BMT, I got HLA tested with my brother in case

of. But just after dx it is not so easy to stay calm and read about

cml, it was a scary time for all of us, and we wanted marry to take

more time to think about options and not to rush into following the

first advice from the first oncologist she saw. As I mentioned on

another post, cml is a rare condition and most oncologists have little

experience with cml patients. I hope I clarified my previous post and

I apologize if you felt offended, and wish sincerely you are not

pissed at me anymore :)

Cheers,

Marcos.

On Mon, Mar 24, 2008 at 6:30 AM, Therese Stone <kidme2003@...> wrote:

>

>

>

>

> Hey Marcos:

>

> It takes a tremendous amount of planning and dx to make any decision

> regarding your medical care. I do not consider what any one of us are going

> through " a game " . I am giving my opinion on my experiences with my treatment

> of CML.

>

> I payed my dues to all of this and have experience to share with those that

> might be backed into the corner I was in. As far as treatment for the CML my

> options were getting very limited. I decided not to wait to blast crisis

> before the latest and greatest trial came along. I needed to take action. My

> CML was past wait and see stage.

>

> The doctors I see all agreed it was time to consider a transplant. After 14

> months of transplant recovery, I think it was a good choice. Any treatment

> we choose should be planned out very carefully. If you choose drugs or

> transplant you need a course of action. Financially, emotionally, mentally,

> insurance, if needed - donors, all need careful planning to survive the

> treatment.

>

> I am pissed you think I feel this is a game, let me tell you something, I

> fought hard to keep my life. We are warriors fighting a battle. Hope we all

> come out on the winning end.

>

> Therese

>

> Marcos Perreau Guimaraes <montereyunderwater@...> wrote: I second

> Zavie. This is not about scare tactics or choosing sides in a

>

>

> football game. BMT is just not anymore the front line treatment of

> cml. No cml specialists advise it for chronic phase patients without

> trying the drugs first, neither LLS, NCF or European cancer

> organisations. Survival and remission rates for newly dx patients are

> a lot better with gleevec alone. If the drugs fail then BMT becomes

> one of the options. Anyway nobody should take this kind of decision

> without getting the opinion of one of the leader cml specialists. CML

> is a rare form of leukemia and most hematologists/oncologists don't

> see enough cml patients to be knowledgeable about current options. I

> am glad the BMT worked for you Theresa, and that you overcame the loss

> of remission with gleevec. And you are right that BMTs are getting

> better, but we don't even know if Marry is responding to the drug. And

> there is also no reason to rush a decision one way or another.

> Marcos.

>

> On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE <rcd1929@...>

> wrote:

> >

> >

> >

> >

> > Hello Marri, I never post to anyone who is considering transplant, as it

> is

> > not an option for me, at 78, so I have no knowledge of it. But if you have

> > not had a second opinion on this, may I suggest that you get one? Dr.

> Druker

> > in Portland Oregon and Dr. Talpaz in Ann Arbor, are to me the two finest

> > doctors in the states. I have had cml for 13 years, and they only gave me

> 5

> > years in 1995, and I'm still around and kicking! And that is because of

> all

> > the new drugs, and there are more in the near future. Good luck with your

> > decision, I know it is not an easy one. Blessings, Bobby

> >

> > Therese Stone <kidme2003@...> wrote: Marri35:

> >

> >

> >

> > One more thing, I don't see choosing a transplant as giving up on life. It

> > actually give you one more option to choosing life. Transplant has been

> done

> > for many, many years. Once you start looking into this option you will see

> > how advanced this medical has become. Don't be archaic with the stats you

> > look at, be up to date. Good Luck.

> >

> > Therese Stone

> >

> > marri35 <tmtip@...> wrote: I saw new oncologist/hematologist...

> he

> > seems very up.. He did his

> > fellowship at Stanford etc. Anyway, I was quite suprised when he told

> > me I had possibly 10 good years with the medications and that

> > eventuality would be tolerance to the medications by CML and eventual

> > progression. I'm 35 and he said I would not approach the 30 to 40

> > years I had left on this earth with everything that was currently

> > available. He then went on to say that BMT is the best option for

> > someone my age and it was best done in the next year or two too

> > increase odds of surviving CML free. I have 4 eligible siblings and 2

> > children (too young to be tested I think.) So, he's telling me I need

> > BMT after I figure how to get some type of ins coverage. He would

> > like to see that happen in the next year if possible. Sigh. I

> > generally agree but little overwhelmed. Who else is my age and what

> > have you been told. I have a lot of problems tolerating Sprycel. I

> > was very SOB yesterday. Got Chest xray and wait to see if there's

> > some fluid. Anyway, looking for your advice.. on how to get through

> > this and where the heck to begin etc. I've read some stuff about BMT,

> > so I have some knowledge etc, I think the logistics is going to kill

> > me. I live in REno. They reccommend going to Seattle or LA (City of

> > Hope). I've been to Stanford... They said that would be OK too.

> > Family in VEgas. Friend in Seattle with twin babies. A friend has mom

> > who lives near STanford. I have two kids, 7 and 2 years (girls). My

> > husband is a sub teacher and on verge of getting contract and

> > possibly insurance but pre existing.... would be 15 to 18 months I

> > think before anything was covered (3 month eligiblity period included

> > and wouldn't start until very late August. Suggestions... Advice...

> > What do you all think?

> >

> > ---------------------------------

> > Looking for last minute shopping deals? Find them fast with Search.

> >

> >

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Guest guest

--

Hi Aliza, Your'e coming in nice and clear

Esther

- In , taina2044@... wrote:

>

> hi guys my email hasn't worked in days just wondering if it is now

> aliza yaffa

>

>

>

> **************Create a Home Theater Like the Pros. Watch the video

on AOL

> Home.

> (http://home.aol.com/diy/home-improvement-eric-stromer?video=15?

ncid=aolhom00030000000001)

>

>

>

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Guest guest

Fellow Warriors-

Thank goodness we are all so passionate about our

friend,our disease. It is complacency that would kill

us. The journey is a private one when it comes down to

it- we each make our own decision- what is right for

one may not be right for another. But life decisions

should be made with as much information as possible.

I love my Hem/Onc but I know he is learning with me.

He is not afraid to consult or do research. He was

not offended when I told him I asked Dr. Druker a

question. The advice on the posts is priceless from

those who have survived and are doing more than

surviving many are even thriving.The technology of CML

meds is evolving daily. I love that we can be so real

with each other with all of are various pains cml

quirks.

We are family- we may not always agree brothers and

sisters but we are bound by our blood . By the way if

I may complain. I feel like crap. Pain in my left

side and right shoulder- different from the usually

cramps and bone pain.Night sweats again. I'm supposed

to be in remission but this doesn't feel good. I

switched from four 100 mg to one 400mg gleevec because

I heard it was easier on the stomach. Now I'm

wondering if I made a mistake. I'm feeling sort of

paranoid- noticed a dark spot on my tongue today. I

don't want to see cancer hiding in every nook and

cranny of my body but... I know we are susceptible to

secondary cancers and I have an almost 14 year old to

raise.

On a more positive note- I am having T- shirts printed

as a fundraiser first for LLS and then for other

cancer research with the logo- ME 2. It answers the

question- Has Cancer impacted your life? well- Me too.

I figure I should be able to sell a shirt to everyone

in the world. The first shipment say- Warrior or

Family or Friend. I'm donating Warrior shirts to

children's hospitals- my goal is that every child

diagnosed with cancer will leave the hospital with a

warrior shirt. I will send a FREE Warrior shirt to

anyone on this post if you send me your T shirt size

and where tos end it.Eventually - I will make

shirts/hats/sweatshirts that say- Cure, Survivor,

Thriving- well you get the picture. 100% of the

profits will go to Cancer Foundations.

Love to you all. We are all on the same side- we are

family.

--- Marcos Perreau Guimaraes

<montereyunderwater@...> wrote:

> Hi Therese,

> I wasn't thinking you chose a BMT without reasons,

> you mentioned

> gleevec stopped working and I can understand you had

> some tough

> decisions to make, and BMT was certainly a sensible

> option at that

> point, I am sincerely glad you did well with it and

> I can only imagine

> you had some really rough time and lot of courage to

> pull through. I

> never suggested you take it as a game, sorry if it

> sounded that way,

> it was just about taking sides, and we sometime tend

> to take sides

> even when it is not a game. Well, before being a cml

> warrior, I have

> been a soldier, I guess I did that too :). My point

> was that the ones

> who talked about other options weren't just trying

> to scare marry just

> because we don't like BMT, I got HLA tested with my

> brother in case

> of. But just after dx it is not so easy to stay calm

> and read about

> cml, it was a scary time for all of us, and we

> wanted marry to take

> more time to think about options and not to rush

> into following the

> first advice from the first oncologist she saw. As I

> mentioned on

> another post, cml is a rare condition and most

> oncologists have little

> experience with cml patients. I hope I clarified my

> previous post and

> I apologize if you felt offended, and wish sincerely

> you are not

> pissed at me anymore :)

> Cheers,

> Marcos.

>

> On Mon, Mar 24, 2008 at 6:30 AM, Therese Stone

> <kidme2003@...> wrote:

> >

> >

> >

> >

> > Hey Marcos:

> >

> > It takes a tremendous amount of planning and dx to

> make any decision

> > regarding your medical care. I do not consider

> what any one of us are going

> > through " a game " . I am giving my opinion on my

> experiences with my treatment

> > of CML.

> >

> > I payed my dues to all of this and have experience

> to share with those that

> > might be backed into the corner I was in. As far

> as treatment for the CML my

> > options were getting very limited. I decided not

> to wait to blast crisis

> > before the latest and greatest trial came along. I

> needed to take action. My

> > CML was past wait and see stage.

> >

> > The doctors I see all agreed it was time to

> consider a transplant. After 14

> > months of transplant recovery, I think it was a

> good choice. Any treatment

> > we choose should be planned out very carefully. If

> you choose drugs or

> > transplant you need a course of action.

> Financially, emotionally, mentally,

> > insurance, if needed - donors, all need careful

> planning to survive the

> > treatment.

> >

> > I am pissed you think I feel this is a game, let

> me tell you something, I

> > fought hard to keep my life. We are warriors

> fighting a battle. Hope we all

> > come out on the winning end.

> >

> > Therese

> >

> > Marcos Perreau Guimaraes

> <montereyunderwater@...> wrote: I second

> > Zavie. This is not about scare tactics or choosing

> sides in a

> >

> >

> > football game. BMT is just not anymore the front

> line treatment of

> > cml. No cml specialists advise it for chronic

> phase patients without

> > trying the drugs first, neither LLS, NCF or

> European cancer

> > organisations. Survival and remission rates for

> newly dx patients are

> > a lot better with gleevec alone. If the drugs fail

> then BMT becomes

> > one of the options. Anyway nobody should take this

> kind of decision

> > without getting the opinion of one of the leader

> cml specialists. CML

> > is a rare form of leukemia and most

> hematologists/oncologists don't

> > see enough cml patients to be knowledgeable about

> current options. I

> > am glad the BMT worked for you Theresa, and that

> you overcame the loss

> > of remission with gleevec. And you are right that

> BMTs are getting

> > better, but we don't even know if Marry is

> responding to the drug. And

> > there is also no reason to rush a decision one way

> or another.

> > Marcos.

> >

> > On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE

> <rcd1929@...>

> > wrote:

> > >

> > >

> > >

> > >

> > > Hello Marri, I never post to anyone who is

> considering transplant, as it

> > is

> > > not an option for me, at 78, so I have no

> knowledge of it. But if you have

> > > not had a second opinion on this, may I suggest

> that you get one? Dr.

> > Druker

> > > in Portland Oregon and Dr. Talpaz in Ann Arbor,

> are to me the two finest

> > > doctors in the states. I have had cml for 13

> years, and they only gave me

> > 5

> > > years in 1995, and I'm still around and kicking!

> And that is because of

> > all

> > > the new drugs, and there are more in the near

> future. Good luck with your

> > > decision, I know it is not an easy one.

> Blessings, Bobby

> > >

> > > Therese Stone <kidme2003@...> wrote:

> Marri35:

> > >

> > >

> > >

> > > One more thing, I don't see choosing a

> transplant as giving up on life. It

> > > actually give you one more option to choosing

> life. Transplant has been

> > done

> > > for many, many years. Once you start looking

> into this option you will see

> > > how advanced this medical has become. Don't be

> archaic with the stats you

> > > look at, be up to date. Good Luck.

> > >

> > > Therese Stone

> > >

> > > marri35 <tmtip@...> wrote: I saw new

> oncologist/hematologist...

> > he

> > > seems very up.. He did his

> > > fellowship at Stanford etc. Anyway, I was quite

> suprised when he told

> > > me I had possibly 10 good years with the

> medications and that

> > > eventuality would be tolerance to the

> medications by CML and eventual

> > > progression. I'm 35 and he said I would not

> approach the 30 to 40

> > > years I had left on this earth with everything

> that was currently

> > > available. He then went on to say that BMT is

> the best option for

> > > someone my age and it was best done in the next

> year or two too

> > > increase odds of surviving CML free. I have 4

> eligible siblings and 2

> > > children (too young to be tested I think.) So,

> he's telling me I need

> > > BMT after I figure how to get some type of ins

> coverage. He would

> > > like to see that happen in the next year if

> possible. Sigh. I

> > > generally agree but little overwhelmed. Who else

> is my age and what

> > > have you been told. I have a lot of problems

> tolerating Sprycel. I

> > > was very SOB yesterday. Got Chest xray and wait

> to see if there's

> > > some fluid. Anyway, looking for your advice.. on

> how to get through

>

=== message truncated ===

________________________________________________________________________________\

____

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Hi China,

I have also some left side/shoulder pain once in a while this last 3

years, even now I am PCRU. I mentioned it to the dr a few times and he

wasn't too concerned, although he did check it up. Pretty much

everything from toes to head on my left side got broken or cut at one

point or another, and my left shoulder is not so good, what probably

doesn't help.

You certainly should tell it to your dr, but no reason to panic. Could

be a lot of things, like gas (mild aerophagia), gall bladder duct

getting irritated by the gleevec, etc. Good post by the way, and yes I

want a t-shirt :) although I can contribute something, it doesn't have

to be free. Size large for me. Thanks a lot,

Take care,

Marcos.

On Mon, Mar 24, 2008 at 7:30 PM, china neal <chimera46@...> wrote:

>

>

>

>

> Fellow Warriors-

>

> Thank goodness we are all so passionate about our

> friend,our disease. It is complacency that would kill

> us. The journey is a private one when it comes down to

> it- we each make our own decision- what is right for

> one may not be right for another. But life decisions

> should be made with as much information as possible.

> I love my Hem/Onc but I know he is learning with me.

> He is not afraid to consult or do research. He was

> not offended when I told him I asked Dr. Druker a

> question. The advice on the posts is priceless from

> those who have survived and are doing more than

> surviving many are even thriving.The technology of CML

> meds is evolving daily. I love that we can be so real

> with each other with all of are various pains cml

> quirks.

>

> We are family- we may not always agree brothers and

> sisters but we are bound by our blood . By the way if

> I may complain. I feel like crap. Pain in my left

> side and right shoulder- different from the usually

> cramps and bone pain.Night sweats again. I'm supposed

> to be in remission but this doesn't feel good. I

> switched from four 100 mg to one 400mg gleevec because

> I heard it was easier on the stomach. Now I'm

> wondering if I made a mistake. I'm feeling sort of

> paranoid- noticed a dark spot on my tongue today. I

> don't want to see cancer hiding in every nook and

> cranny of my body but... I know we are susceptible to

> secondary cancers and I have an almost 14 year old to

> raise.

>

> On a more positive note- I am having T- shirts printed

> as a fundraiser first for LLS and then for other

> cancer research with the logo- ME 2. It answers the

> question- Has Cancer impacted your life? well- Me too.

> I figure I should be able to sell a shirt to everyone

> in the world. The first shipment say- Warrior or

> Family or Friend. I'm donating Warrior shirts to

> children's hospitals- my goal is that every child

> diagnosed with cancer will leave the hospital with a

> warrior shirt. I will send a FREE Warrior shirt to

> anyone on this post if you send me your T shirt size

> and where tos end it.Eventually - I will make

> shirts/hats/sweatshirts that say- Cure, Survivor,

> Thriving- well you get the picture. 100% of the

> profits will go to Cancer Foundations.

>

> Love to you all. We are all on the same side- we are

> family.

>

> --- Marcos Perreau Guimaraes

>

>

> <montereyunderwater@...> wrote:

>

> > Hi Therese,

> > I wasn't thinking you chose a BMT without reasons,

> > you mentioned

> > gleevec stopped working and I can understand you had

> > some tough

> > decisions to make, and BMT was certainly a sensible

> > option at that

> > point, I am sincerely glad you did well with it and

> > I can only imagine

> > you had some really rough time and lot of courage to

> > pull through. I

> > never suggested you take it as a game, sorry if it

> > sounded that way,

> > it was just about taking sides, and we sometime tend

> > to take sides

> > even when it is not a game. Well, before being a cml

> > warrior, I have

> > been a soldier, I guess I did that too :). My point

> > was that the ones

> > who talked about other options weren't just trying

> > to scare marry just

> > because we don't like BMT, I got HLA tested with my

> > brother in case

> > of. But just after dx it is not so easy to stay calm

> > and read about

> > cml, it was a scary time for all of us, and we

> > wanted marry to take

> > more time to think about options and not to rush

> > into following the

> > first advice from the first oncologist she saw. As I

> > mentioned on

> > another post, cml is a rare condition and most

> > oncologists have little

> > experience with cml patients. I hope I clarified my

> > previous post and

> > I apologize if you felt offended, and wish sincerely

> > you are not

> > pissed at me anymore :)

> > Cheers,

> > Marcos.

> >

> > On Mon, Mar 24, 2008 at 6:30 AM, Therese Stone

> > <kidme2003@...> wrote:

> > >

> > >

> > >

> > >

> > > Hey Marcos:

> > >

> > > It takes a tremendous amount of planning and dx to

> > make any decision

> > > regarding your medical care. I do not consider

> > what any one of us are going

> > > through " a game " . I am giving my opinion on my

> > experiences with my treatment

> > > of CML.

> > >

> > > I payed my dues to all of this and have experience

> > to share with those that

> > > might be backed into the corner I was in. As far

> > as treatment for the CML my

> > > options were getting very limited. I decided not

> > to wait to blast crisis

> > > before the latest and greatest trial came along. I

> > needed to take action. My

> > > CML was past wait and see stage.

> > >

> > > The doctors I see all agreed it was time to

> > consider a transplant. After 14

> > > months of transplant recovery, I think it was a

> > good choice. Any treatment

> > > we choose should be planned out very carefully. If

> > you choose drugs or

> > > transplant you need a course of action.

> > Financially, emotionally, mentally,

> > > insurance, if needed - donors, all need careful

> > planning to survive the

> > > treatment.

> > >

> > > I am pissed you think I feel this is a game, let

> > me tell you something, I

> > > fought hard to keep my life. We are warriors

> > fighting a battle. Hope we all

> > > come out on the winning end.

> > >

> > > Therese

> > >

> > > Marcos Perreau Guimaraes

> > <montereyunderwater@...> wrote: I second

> > > Zavie. This is not about scare tactics or choosing

> > sides in a

> > >

> > >

> > > football game. BMT is just not anymore the front

> > line treatment of

> > > cml. No cml specialists advise it for chronic

> > phase patients without

> > > trying the drugs first, neither LLS, NCF or

> > European cancer

> > > organisations. Survival and remission rates for

> > newly dx patients are

> > > a lot better with gleevec alone. If the drugs fail

> > then BMT becomes

> > > one of the options. Anyway nobody should take this

> > kind of decision

> > > without getting the opinion of one of the leader

> > cml specialists. CML

> > > is a rare form of leukemia and most

> > hematologists/oncologists don't

> > > see enough cml patients to be knowledgeable about

> > current options. I

> > > am glad the BMT worked for you Theresa, and that

> > you overcame the loss

> > > of remission with gleevec. And you are right that

> > BMTs are getting

> > > better, but we don't even know if Marry is

> > responding to the drug. And

> > > there is also no reason to rush a decision one way

> > or another.

> > > Marcos.

> > >

> > > On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE

> > <rcd1929@...>

> > > wrote:

> > > >

> > > >

> > > >

> > > >

> > > > Hello Marri, I never post to anyone who is

> > considering transplant, as it

> > > is

> > > > not an option for me, at 78, so I have no

> > knowledge of it. But if you have

> > > > not had a second opinion on this, may I suggest

> > that you get one? Dr.

> > > Druker

> > > > in Portland Oregon and Dr. Talpaz in Ann Arbor,

> > are to me the two finest

> > > > doctors in the states. I have had cml for 13

> > years, and they only gave me

> > > 5

> > > > years in 1995, and I'm still around and kicking!

> > And that is because of

> > > all

> > > > the new drugs, and there are more in the near

> > future. Good luck with your

> > > > decision, I know it is not an easy one.

> > Blessings, Bobby

> > > >

> > > > Therese Stone <kidme2003@...> wrote:

> > Marri35:

> > > >

> > > >

> > > >

> > > > One more thing, I don't see choosing a

> > transplant as giving up on life. It

> > > > actually give you one more option to choosing

> > life. Transplant has been

> > > done

> > > > for many, many years. Once you start looking

> > into this option you will see

> > > > how advanced this medical has become. Don't be

> > archaic with the stats you

> > > > look at, be up to date. Good Luck.

> > > >

> > > > Therese Stone

> > > >

> > > > marri35 <tmtip@...> wrote: I saw new

> > oncologist/hematologist...

> > > he

> > > > seems very up.. He did his

> > > > fellowship at Stanford etc. Anyway, I was quite

> > suprised when he told

> > > > me I had possibly 10 good years with the

> > medications and that

> > > > eventuality would be tolerance to the

> > medications by CML and eventual

> > > > progression. I'm 35 and he said I would not

> > approach the 30 to 40

> > > > years I had left on this earth with everything

> > that was currently

> > > > available. He then went on to say that BMT is

> > the best option for

> > > > someone my age and it was best done in the next

> > year or two too

> > > > increase odds of surviving CML free. I have 4

> > eligible siblings and 2

> > > > children (too young to be tested I think.) So,

> > he's telling me I need

> > > > BMT after I figure how to get some type of ins

> > coverage. He would

> > > > like to see that happen in the next year if

> > possible. Sigh. I

> > > > generally agree but little overwhelmed. Who else

> > is my age and what

> > > > have you been told. I have a lot of problems

> > tolerating Sprycel. I

> > > > was very SOB yesterday. Got Chest xray and wait

> > to see if there's

> > > > some fluid. Anyway, looking for your advice.. on

> > how to get through

> >

> === message truncated ===

>

> __________________________________________________________

>

> Be a better friend, newshound, and

> know-it-all with Mobile. Try it now.

> http://mobile./;_ylt=Ahu06i62sR8HDtDypao8Wcj9tAcJ

>

>

>

--

Marcos Perreau Guimaraes

Suppes Brain Lab

Ventura Hall - CSLI

Stanford University

220 Panama street

Stanford CA 94305-4101

650 614 2305

650 630 5015 (cell)

marcospg@...

montereyunderwater@...

www.stanford.edu/~marcospg/

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Guest guest

Size large and even though I am in Canada , anything I can do to help including

donation just say the work. Thanks Eva

From: china neal

Sent: Monday, March 24, 2008 10:30 PM

Subject: Re: [ ] BMT

Fellow Warriors-

Thank goodness we are all so passionate about our

friend,our disease. It is complacency that would kill

us. The journey is a private one when it comes down to

it- we each make our own decision- what is right for

one may not be right for another. But life decisions

should be made with as much information as possible.

I love my Hem/Onc but I know he is learning with me.

He is not afraid to consult or do research. He was

not offended when I told him I asked Dr. Druker a

question. The advice on the posts is priceless from

those who have survived and are doing more than

surviving many are even thriving.The technology of CML

meds is evolving daily. I love that we can be so real

with each other with all of are various pains cml

quirks.

We are family- we may not always agree brothers and

sisters but we are bound by our blood . By the way if

I may complain. I feel like crap. Pain in my left

side and right shoulder- different from the usually

cramps and bone pain.Night sweats again. I'm supposed

to be in remission but this doesn't feel good. I

switched from four 100 mg to one 400mg gleevec because

I heard it was easier on the stomach. Now I'm

wondering if I made a mistake. I'm feeling sort of

paranoid- noticed a dark spot on my tongue today. I

don't want to see cancer hiding in every nook and

cranny of my body but... I know we are susceptible to

secondary cancers and I have an almost 14 year old to

raise.

On a more positive note- I am having T- shirts printed

as a fundraiser first for LLS and then for other

cancer research with the logo- ME 2. It answers the

question- Has Cancer impacted your life? well- Me too.

I figure I should be able to sell a shirt to everyone

in the world. The first shipment say- Warrior or

Family or Friend. I'm donating Warrior shirts to

children's hospitals- my goal is that every child

diagnosed with cancer will leave the hospital with a

warrior shirt. I will send a FREE Warrior shirt to

anyone on this post if you send me your T shirt size

and where tos end it.Eventually - I will make

shirts/hats/sweatshirts that say- Cure, Survivor,

Thriving- well you get the picture. 100% of the

profits will go to Cancer Foundations.

Love to you all. We are all on the same side- we are

family.

--- Marcos Perreau Guimaraes

<montereyunderwater@...> wrote:

> Hi Therese,

> I wasn't thinking you chose a BMT without reasons,

> you mentioned

> gleevec stopped working and I can understand you had

> some tough

> decisions to make, and BMT was certainly a sensible

> option at that

> point, I am sincerely glad you did well with it and

> I can only imagine

> you had some really rough time and lot of courage to

> pull through. I

> never suggested you take it as a game, sorry if it

> sounded that way,

> it was just about taking sides, and we sometime tend

> to take sides

> even when it is not a game. Well, before being a cml

> warrior, I have

> been a soldier, I guess I did that too :). My point

> was that the ones

> who talked about other options weren't just trying

> to scare marry just

> because we don't like BMT, I got HLA tested with my

> brother in case

> of. But just after dx it is not so easy to stay calm

> and read about

> cml, it was a scary time for all of us, and we

> wanted marry to take

> more time to think about options and not to rush

> into following the

> first advice from the first oncologist she saw. As I

> mentioned on

> another post, cml is a rare condition and most

> oncologists have little

> experience with cml patients. I hope I clarified my

> previous post and

> I apologize if you felt offended, and wish sincerely

> you are not

> pissed at me anymore :)

> Cheers,

> Marcos.

>

> On Mon, Mar 24, 2008 at 6:30 AM, Therese Stone

> <kidme2003@...> wrote:

> >

> >

> >

> >

> > Hey Marcos:

> >

> > It takes a tremendous amount of planning and dx to

> make any decision

> > regarding your medical care. I do not consider

> what any one of us are going

> > through " a game " . I am giving my opinion on my

> experiences with my treatment

> > of CML.

> >

> > I payed my dues to all of this and have experience

> to share with those that

> > might be backed into the corner I was in. As far

> as treatment for the CML my

> > options were getting very limited. I decided not

> to wait to blast crisis

> > before the latest and greatest trial came along. I

> needed to take action. My

> > CML was past wait and see stage.

> >

> > The doctors I see all agreed it was time to

> consider a transplant. After 14

> > months of transplant recovery, I think it was a

> good choice. Any treatment

> > we choose should be planned out very carefully. If

> you choose drugs or

> > transplant you need a course of action.

> Financially, emotionally, mentally,

> > insurance, if needed - donors, all need careful

> planning to survive the

> > treatment.

> >

> > I am pissed you think I feel this is a game, let

> me tell you something, I

> > fought hard to keep my life. We are warriors

> fighting a battle. Hope we all

> > come out on the winning end.

> >

> > Therese

> >

> > Marcos Perreau Guimaraes

> <montereyunderwater@...> wrote: I second

> > Zavie. This is not about scare tactics or choosing

> sides in a

> >

> >

> > football game. BMT is just not anymore the front

> line treatment of

> > cml. No cml specialists advise it for chronic

> phase patients without

> > trying the drugs first, neither LLS, NCF or

> European cancer

> > organisations. Survival and remission rates for

> newly dx patients are

> > a lot better with gleevec alone. If the drugs fail

> then BMT becomes

> > one of the options. Anyway nobody should take this

> kind of decision

> > without getting the opinion of one of the leader

> cml specialists. CML

> > is a rare form of leukemia and most

> hematologists/oncologists don't

> > see enough cml patients to be knowledgeable about

> current options. I

> > am glad the BMT worked for you Theresa, and that

> you overcame the loss

> > of remission with gleevec. And you are right that

> BMTs are getting

> > better, but we don't even know if Marry is

> responding to the drug. And

> > there is also no reason to rush a decision one way

> or another.

> > Marcos.

> >

> > On Sun, Mar 23, 2008 at 9:45 AM, ROBERTA DOYLE

> <rcd1929@...>

> > wrote:

> > >

> > >

> > >

> > >

> > > Hello Marri, I never post to anyone who is

> considering transplant, as it

> > is

> > > not an option for me, at 78, so I have no

> knowledge of it. But if you have

> > > not had a second opinion on this, may I suggest

> that you get one? Dr.

> > Druker

> > > in Portland Oregon and Dr. Talpaz in Ann Arbor,

> are to me the two finest

> > > doctors in the states. I have had cml for 13

> years, and they only gave me

> > 5

> > > years in 1995, and I'm still around and kicking!

> And that is because of

> > all

> > > the new drugs, and there are more in the near

> future. Good luck with your

> > > decision, I know it is not an easy one.

> Blessings, Bobby

> > >

> > > Therese Stone <kidme2003@...> wrote:

> Marri35:

> > >

> > >

> > >

> > > One more thing, I don't see choosing a

> transplant as giving up on life. It

> > > actually give you one more option to choosing

> life. Transplant has been

> > done

> > > for many, many years. Once you start looking

> into this option you will see

> > > how advanced this medical has become. Don't be

> archaic with the stats you

> > > look at, be up to date. Good Luck.

> > >

> > > Therese Stone

> > >

> > > marri35 <tmtip@...> wrote: I saw new

> oncologist/hematologist...

> > he

> > > seems very up.. He did his

> > > fellowship at Stanford etc. Anyway, I was quite

> suprised when he told

> > > me I had possibly 10 good years with the

> medications and that

> > > eventuality would be tolerance to the

> medications by CML and eventual

> > > progression. I'm 35 and he said I would not

> approach the 30 to 40

> > > years I had left on this earth with everything

> that was currently

> > > available. He then went on to say that BMT is

> the best option for

> > > someone my age and it was best done in the next

> year or two too

> > > increase odds of surviving CML free. I have 4

> eligible siblings and 2

> > > children (too young to be tested I think.) So,

> he's telling me I need

> > > BMT after I figure how to get some type of ins

> coverage. He would

> > > like to see that happen in the next year if

> possible. Sigh. I

> > > generally agree but little overwhelmed. Who else

> is my age and what

> > > have you been told. I have a lot of problems

> tolerating Sprycel. I

> > > was very SOB yesterday. Got Chest xray and wait

> to see if there's

> > > some fluid. Anyway, looking for your advice.. on

> how to get through

>

=== message truncated ===

__________________________________________________________

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know-it-all with Mobile. Try it now.

http://mobile./;_ylt=Ahu06i62sR8HDtDypao8Wcj9tAcJ

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