Re: Plant derivative attacks the roots of leukemia - parthenolide - cure

[Guest guest]

Holy Toledo!

From: cousineaugilles@...

Date: Wed, 27 Feb 2008 23:26:03 +0000

Subject: [ ] Plant derivative attacks the roots of leukemia - parthenolide

- cure

Hi,

Do you think that the parthenolide will be a natural cure for CML?

" " A daisy-like plant known as Feverfew or Bachelor's Button, found in

gardens across North America, is the source of an agent that kills

human leukemia stem cells like no other single therapy, scientists at

the University of Rochester Medical Center's P. Wilmot Cancer

Center have discovered. Their investigation is reported in the online

edition of the journal, Blood. " "

http://www.eurekalert.org/pub_releases/2005-02/uorm-pda022205.php

See also:

http://en.wikinews.org/wiki/Feverfew_compound_gets_at_leukemia_roots

http://en.wikipedia.org/wiki/Parthenolide

Regards,

Gilles Cousineau (age 54)

Montreal, Canada

dxd (Essential thrombocytemia) August 2004

Treated with Hydrea and Agylin

High Platelet count(1400000)

dxd (CML ) June 2005

Treated with Gleevec (400mg)

_________________________________________________________________

Climb to the top of the charts! Play the word scramble challenge with star

power.

http://club.live.com/star_shuffle.aspx?icid=starshuffle_wlmailtextlink_jan

[Guest guest]

A few things to keep in mind when reading this kind of articles :

- It takes a long time for a new compound to lead to actual medication

(in general more than a decade), and most of the promising ones don't

lead to anything.

- Gleevec (Imatinib) was a huge step forward because it is based on a

better understanding of the mechanisms of the cml, and of cancer in

general. It is proven now to be effective in the long term for the

large majority of patients. Side effects are orders of magnitude

lesser than classic cancer treatments.

- Gleevec (and the other durgs Sprycel, Tasigna, etc) interfers with,

and ultimately kills blood stem cells, but there are different kinds

of stem cell and drs think gleevec may not affect, or not enough, stem

cells higher up in the differentiation chain. The mechanisms of blood

production are very complex and not everything is understood. We have

the good luck that, even if cml was a very bad cancer still 10 years

ago, it is one of the best understood, which is why reserchers are not

as much in the dark than for most other cancers. But it doesn't make

as good a story as a new plant agent that cures cancer.

Marcos.

On Wed, Feb 27, 2008 at 6:01 PM, Rosen Lum

<rrosenlum@...> wrote:

>

>

>

>

>

> Holy Toledo!

>

>

> From: cousineaugilles@...

> Date: Wed, 27 Feb 2008 23:26:03 +0000

> Subject: [ ] Plant derivative attacks the roots of leukemia -

> parthenolide - cure

>

>

> Hi,

>

> Do you think that the parthenolide will be a natural cure for CML?

>

> " " A daisy-like plant known as Feverfew or Bachelor's Button, found in

>

> gardens across North America, is the source of an agent that kills

>

> human leukemia stem cells like no other single therapy, scientists at

>

> the University of Rochester Medical Center's P. Wilmot Cancer

>

> Center have discovered. Their investigation is reported in the online

>

> edition of the journal, Blood. " "

>

> http://www.eurekalert.org/pub_releases/2005-02/uorm-pda022205.php

>

> See also:

>

> http://en.wikinews.org/wiki/Feverfew_compound_gets_at_leukemia_roots

>

> http://en.wikipedia.org/wiki/Parthenolide

>

> Regards,

>

> Gilles Cousineau (age 54)

>

> Montreal, Canada

>

> dxd (Essential thrombocytemia) August 2004

>

> Treated with Hydrea and Agylin

>

> High Platelet count(1400000)

>

> dxd (CML ) June 2005

>

> Treated with Gleevec (400mg)

>

> __________________________________________________________

> Climb to the top of the charts! Play the word scramble challenge with star

> power.

> http://club.live.com/star_shuffle.aspx?icid=starshuffle_wlmailtextlink_jan

>

>

[Guest guest]

Gilles,

This is strictly opinion on my part. I worked for a well-known supplement

company in Los Angeles for almost three years as executive assistant to the

founder and president who is a brilliant man.

I observed the supplement industry with great interest and this was at least

five years before I was dianosed with CML. My opinion is that there are

supplements that help symptoms of some simple conditions such as calcium, the

various well-known vitamins and there are others that some people swear help

them.

My employer did not engage in all the hype as it id practiced by some. Perhaps

feverfew or the substance within it that you mentioned would be helpful in

research but I sincerely doubt that feverfew alone would do anything for cml

patients. I say that if someone is researching it as a possibility in

combination with something else or in a different form then that's interesting

for the future.

I, personally, will not be running out to buy a jar of feverfew.

Thanks for the information, though. I don't read the journals but it's good

that you're doing that. Did the journal have a judgement about feverfew and its

viability?

Cheers,

L

[ ] Plant derivative attacks the roots of leukemia - parthenolide

- cure

Hi,

Do you think that the parthenolide will be a natural cure for CML?

" " A daisy-like plant known as Feverfew or Bachelor's Button, found in

gardens across North America, is the source of an agent that kills

human leukemia stem cells like no other single therapy, scientists at

the University of Rochester Medical Center's P. Wilmot Cancer

Center have discovered. Their investigation is reported in the online

edition of the journal, Blood. " "

http://www.eurekalert.org/pub_releases/2005-02/uorm-pda022205.php

See also:

http://en.wikinews.org/wiki/Feverfew_compound_gets_at_leukemia_roots

http://en.wikipedia.org/wiki/Parthenolide

Regards,

Gilles Cousineau (age 54)

Montreal, Canada

dxd (Essential thrombocytemia) August 2004

Treated with Hydrea and Agylin

High Platelet count(1400000)

dxd (CML ) June 2005

Treated with Gleevec (400mg)

[Guest guest]

Hi,

New links about Parthenolide:

Parthenolide Analog-Blood Cancer Clinical Trial Soon To Begin In

England

http://margaret.healthblogs.org/2007/10/03/parthenolide-analog-blood-

cancer-clinical-trial-soon-to-begin-in-england/

Peekaboo Update, New (Cancer) Stem Cell Clinical Trial And Another

Good Reason To Take Curcumin

http://margaret.healthblogs.org/2007/11/29/peekaboo-update-new-

clinical-cancer-stem-trial-and-another-good-reason-to-take-curcumin/

Daisies Lead Scientists Down Path To New Leukemia Drug

ScienceDaily (Oct. 5, 2007)

http://www.sciencedaily.com/releases/2007/10/071002131128.htm

Daisies lead to new leukemia drug

Wednesday, October 03, 2007;

http://www.tradingmarkets.com/.site/news/Stock%20News/667738/?

hcode=relatednews

New Leukemia Drug Stems From Feverfew

Main Category: Lymphoma / Leukemia News

Article Date: 03 Oct 2007 - 4:00 PDT

http://www.cmlsupport.org.uk/?q=node/573

SWCRF RESEARCHER BRINGS INNOVATIVE AGENT THAT

DESTROYS LEUKEMIA STEM CELLS TO PHASE 1 TRIAL IN HUMANS

http://www.waxmancancer.org/newsletter/jan2008/index.htm

Regards,

>

>

> Gilles Cousineau (age 54)

> Montreal, Canada

>

> dxd (Essential thrombocytemia) August 2004

> Treated with Hydrea and Agylin

> High Platelet count(1400000)

>

> dxd (CML ) June 2005

> Treated with Gleevec (400mg)

--- In , " Gilles Cousineau " <cousineaugilles@...>

wrote:

>

> Hi,

>

> Do you think that the parthenolide will be a natural cure for

CML?

>

>

> " " A daisy-like plant known as Feverfew or Bachelor's Button, found

in

> gardens across North America, is the source of an agent that kills

> human leukemia stem cells like no other single therapy, scientists

at

> the University of Rochester Medical Center's P. Wilmot Cancer

> Center have discovered. Their investigation is reported in the

online

> edition of the journal, Blood. " "

> http://www.eurekalert.org/pub_releases/2005-02/uorm-pda022205.php

>

> See also:

>

>

http://en.wikinews.org/wiki/Feverfew_compound_gets_at_leukemia_roots

> http://en.wikipedia.org/wiki/Parthenolide

>

> Regards,

>

>

> Gilles Cousineau (age 54)

> Montreal, Canada

>

> dxd (Essential thrombocytemia) August 2004

> Treated with Hydrea and Agylin

> High Platelet count(1400000)

>

> dxd (CML ) June 2005

> Treated with Gleevec (400mg)

>