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Hi Group, because of problems with PE, my Sprycel dose has been lowered, and I

have to have labs done every week. Normally the wbc is around 3,000. Because I

was off Sprycel a while back, the wbc gradually increased, up to 11,000 and

started to go down, to 8,000 when they increased the dose to 40. Today the wbc

was up to 12,000, so I am a teensy

bit concerned. I go to see Dr. Talpaz March 20 for a visit, a bma and labs,

I'll most likely find out then if he will keep me on Sprycel or switch me to

Tasi. I'll keep you posted, but I sure wish I could stay on Sprycel, I have no

side effects, as long as I can keep PE at bay.

Bobby

a (Bobby) Doyle

Brecksville, Ohio, USA

DX 05/1995

02/2000 - Gleevec Trial/OHSU

06/2002 - Gleevec/Trisenox Trial/OHSU

06/2003 - Gleevec/Zarnestra Trial/OHSU

04/2004 - Sprycel Trial/MDACC, CCR in 10 months

#840 - Zavie's Zero Club

09/2006 - out of CCR

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Hi Sharon, I think Tasi will be fine too, we will just have to get adjusted to

it, like we did Gleevec at first. I am hoping if they do put me on it, it is

the 400 mg, not the 800 to start.

Good Luck, Bobby

Sharon & Denny <onthewtr@...> wrote:

Hi Bobby,

I went through the same thing. I was at 70mg twice a day and PCRU. Then I

lowered it to 50 Mg twice a day and got PE. Strange huh?

So I am starting Tasi this Wed. But my WBC shot up just before they drained

the fluid. Then went back down to 4000. I had a PCR test and waiting for the

results. It will be my Base Line before I start Tasi. I did very well on

Sprycel for three years. Hardly any side effects. I am worried about

starting Tasi but have to do it!!!

Sharon

_____

From: [mailto: ] On Behalf Of

ROBERTA DOYLE

Sent: Monday, March 10, 2008 9:34 PM

Subject: [ ] labs

Hi Group, because of problems with PE, my Sprycel dose has been lowered, and

I have to have labs done every week. Normally the wbc is around 3,000.

Because I was off Sprycel a while back, the wbc gradually increased, up to

11,000 and started to go down, to 8,000 when they increased the dose to 40.

Today the wbc was up to 12,000, so I am a teensy

bit concerned. I go to see Dr. Talpaz March 20 for a visit, a bma and labs,

I'll most likely find out then if he will keep me on Sprycel or switch me to

Tasi. I'll keep you posted, but I sure wish I could stay on Sprycel, I have

no side effects, as long as I can keep PE at bay.

Bobby

a (Bobby) Doyle

Brecksville, Ohio, USA

DX 05/1995

02/2000 - Gleevec Trial/OHSU

06/2002 - Gleevec/Trisenox Trial/OHSU

06/2003 - Gleevec/Zarnestra Trial/OHSU

04/2004 - Sprycel Trial/MDACC, CCR in 10 months

#840 - Zavie's Zero Club

09/2006 - out of CCR

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