Guest guest Posted March 14, 2008 Report Share Posted March 14, 2008 Marcos- What great news. Congrats!! Some things just take patience huh? Enjoy your great news and hope it continues for years to come!!!!! Sincerest wishes- Hugs and Hope- 35 CML 5/13/05 Gleevec 800mg until 8/07 Spyrcel 100 mg since 9/07 Wife and mother of 3 (12,9,7) # 907 in Zavie's Zero Club **************It's Tax Time! Get tips, forms, and advice on AOL Money & Finance. (http://money.aol.com/tax?NCID=aolprf00030000000001) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 14, 2008 Report Share Posted March 14, 2008 Congratulations Marcos, Wonderful....Truly Wonderful. Now if we can just get you to become a Football fan so you can watch my nephew play his senior year at Stanford! With warmest regards, Florida This message (including any attachments) contains confidential information intended for a specific individual and purpose, and is protected by law. If you are not the intended recipient, you should delete this message, and please advise me of your receipt. Any disclosure, copying, or distribution of this message, or the taking of any action based on it, is strictly prohibited. In a message dated 3/14/2008 3:05:01 P.M. Eastern Daylight Time, montereyunderwater@... writes: I just got my hemato on the phone for the last PCR results and, finally, after 3 years short of MMR and being called names like suboptimal, I am now PCRU. That was quite a surprise, I was hoping that maybe I d get to the 3 log reduction this time (2.8 four months ago), but PCRU is about 2 log (100 fold) down from 2.8 with the sensitivity of Stanford lab. It looks like somewhere during these 4 months the bug lost a big battle. Here a bit of what happened since dx : Dx march 2005 BMB 20/20 ph+, FISH 100% ph+, WBC 252, spleen the size of a melon, 135 lbs for 6'2 (I am in general at 175-180) about 10 days hydrea, then gleevec 400 mg/day Hematologic remission in 2-3 weeks, cleared to dive one month after September 2005, BMB 0/20 ph+, FISH 7% March 2006, BMB 0/20, FISH 0% I don't have all the numbers at the office but I had a pcr every 4 months since and for one year (to about march 2007) it stayed around 2.6 log reduction. At that point I saw a cml specialist in Paris that did a dosage of gleevec in the plasma and it was a little low, about 600 when the optimal value is 1000. She said she advised her patients in my case to change to 600mg of gleevec but I wasn't too hot about that as I was afraid that with more side effects than I have now I wouldn't be able to endure the long 2h+ decompression stops of the deep dives. She understood my reasons and advised to wait and see for a couple of pcr tests. The next PCR had a 2 fold reduction to about -2.7 log, and the next was at -2.8 log. So I stayed on 400mg. And this morning PCRU. Marcos. Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 630 5015 (cell) _marcospg@...@mar_ (mailto:marcospg@...) _montereyunderwater@montereyu_ (mailto:montereyunderwater@...) www.stanford.www.stanford. **************It's Tax Time! Get tips, forms, and advice on AOL Money & Finance. (http://money.aol.com/tax?NCID=aolprf00030000000001) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 14, 2008 Report Share Posted March 14, 2008 I just got my hemato on the phone for the last PCR results and, finally, after 3 years short of MMR and being called names like suboptimal, I am now PCRU. That was quite a surprise, I was hoping that maybe I d get to the 3 log reduction this time (2.8 four months ago), but PCRU is about 2 log (100 fold) down from 2.8 with the sensitivity of Stanford lab. It looks like somewhere during these 4 months the bug lost a big battle. Here a bit of what happened since dx : Dx march 2005 BMB 20/20 ph+, FISH 100% ph+, WBC 252, spleen the size of a melon, 135 lbs for 6'2 (I am in general at 175-180) about 10 days hydrea, then gleevec 400 mg/day Hematologic remission in 2-3 weeks, cleared to dive one month after September 2005, BMB 0/20 ph+, FISH 7% March 2006, BMB 0/20, FISH 0% I don't have all the numbers at the office but I had a pcr every 4 months since and for one year (to about march 2007) it stayed around 2.6 log reduction. At that point I saw a cml specialist in Paris that did a dosage of gleevec in the plasma and it was a little low, about 600 when the optimal value is 1000. She said she advised her patients in my case to change to 600mg of gleevec but I wasn't too hot about that as I was afraid that with more side effects than I have now I wouldn't be able to endure the long 2h+ decompression stops of the deep dives. She understood my reasons and advised to wait and see for a couple of pcr tests. The next PCR had a 2 fold reduction to about -2.7 log, and the next was at -2.8 log. So I stayed on 400mg. And this morning PCRU. Marcos. Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 630 5015 (cell) marcospg@... montereyunderwater@... www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 14, 2008 Report Share Posted March 14, 2008 That's great Marcos, or as some might say " good on 'ya ! Bobby alizayaffagutierrez <taina2044@...> wrote: - congratulatios and may it continue to get better, gleevec rocks aliza yaffa rochester n.y. -- In , " Marcos Perreau Guimaraes " <montereyunderwater@...> wrote: > > I just got my hemato on the phone for the last PCR results and, > finally, after 3 years short of MMR and being called names like > suboptimal, I am now PCRU. That was quite a surprise, I was hoping > that maybe I d get to the 3 log reduction this time (2.8 four months > ago), but PCRU is about 2 log (100 fold) down from 2.8 with the > sensitivity of Stanford lab. It looks like somewhere during these 4 > months the bug lost a big battle. > Here a bit of what happened since dx : > Dx march 2005 BMB 20/20 ph+, FISH 100% ph+, WBC 252, spleen the size > of a melon, 135 lbs for 6'2 (I am in general at 175-180) > about 10 days hydrea, then gleevec 400 mg/day > Hematologic remission in 2-3 weeks, cleared to dive one month after > September 2005, BMB 0/20 ph+, FISH 7% > March 2006, BMB 0/20, FISH 0% > I don't have all the numbers at the office but I had a pcr every 4 > months since and for one year (to about march 2007) it stayed around > 2.6 log reduction. At that point I saw a cml specialist in Paris that > did a dosage of gleevec in the plasma and it was a little low, about > 600 when the optimal value is 1000. She said she advised her patients > in my case to change to 600mg of gleevec but I wasn't too hot about > that as I was afraid that with more side effects than I have now I > wouldn't be able to endure the long 2h+ decompression stops of the > deep dives. She understood my reasons and advised to wait and see for > a couple of pcr tests. The next PCR had a 2 fold reduction to about > -2.7 log, and the next was at -2.8 log. So I stayed on 400mg. And this > morning PCRU. > Marcos. > > > Marcos Perreau Guimaraes > Suppes Brain Lab > Ventura Hall - CSLI > Stanford University > 220 Panama street > Stanford CA 94305-4101 > 650 614 2305 > 650 630 5015 (cell) > marcospg@... > montereyunderwater@... > www.stanford.edu/~marcospg/ > a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840 - Zavie's Zero Club 09/2006 - out of CCR Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 14, 2008 Report Share Posted March 14, 2008 Marcos that's absolutely fabulous! Congratulations and I hope you do something special to celebrate. Tracey Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2008 Report Share Posted March 15, 2008 Thanks everybody. I certainly will celebrate Marcos. On Fri, Mar 14, 2008 at 3:42 PM, Tracey <traceyincanada@...> wrote: > > > > > Marcos that's absolutely fabulous! Congratulations and I hope you do > something special to celebrate. > > Tracey > > -- Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 630 5015 (cell) marcospg@... montereyunderwater@... www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2008 Report Share Posted March 16, 2008 Hi Marcos - CONGRATULATIONS! That is a fantastic news. Regards, from Downunder _____ From: [mailto: ] On Behalf Of Marcos Perreau Guimaraes Sent: Saturday, 15 March 2008 6:04 AM Subject: [ ] PCRU I just got my hemato on the phone for the last PCR results and, finally, after 3 years short of MMR and being called names like suboptimal, I am now PCRU. That was quite a surprise, I was hoping that maybe I d get to the 3 log reduction this time (2.8 four months ago), but PCRU is about 2 log (100 fold) down from 2.8 with the sensitivity of Stanford lab. It looks like somewhere during these 4 months the bug lost a big battle. Here a bit of what happened since dx : Dx march 2005 BMB 20/20 ph+, FISH 100% ph+, WBC 252, spleen the size of a melon, 135 lbs for 6'2 (I am in general at 175-180) about 10 days hydrea, then gleevec 400 mg/day Hematologic remission in 2-3 weeks, cleared to dive one month after September 2005, BMB 0/20 ph+, FISH 7% March 2006, BMB 0/20, FISH 0% I don't have all the numbers at the office but I had a pcr every 4 months since and for one year (to about march 2007) it stayed around 2.6 log reduction. At that point I saw a cml specialist in Paris that did a dosage of gleevec in the plasma and it was a little low, about 600 when the optimal value is 1000. She said she advised her patients in my case to change to 600mg of gleevec but I wasn't too hot about that as I was afraid that with more side effects than I have now I wouldn't be able to endure the long 2h+ decompression stops of the deep dives. She understood my reasons and advised to wait and see for a couple of pcr tests. The next PCR had a 2 fold reduction to about -2.7 log, and the next was at -2.8 log. So I stayed on 400mg. And this morning PCRU. Marcos. Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 630 5015 (cell) marcospgcsli (DOT) <mailto:marcospg%40csli.stanford.edu> stanford.edu montereyunderwater@ <mailto:montereyunderwater%40gmail.com> gmail.com www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2008 Report Share Posted March 17, 2008 Congratulations Marcos! I am so excited for you :-) ez Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2008 Report Share Posted October 16, 2008 Bob ! Great job, keep it up and know that you are winning the battle! Matt Florida [ ] PCRU Hi folks, Just got my latest (10/1/08) Quant. PCR back--I'm still PCRU. YEAH!!!!!!!!!!!!!!!! Bob , Granger, Indiana Zavie Club # 54 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2008 Report Share Posted October 16, 2008 DOUBLE YEAH !!!!!!!! Bobby a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840 - Zavie's Zero Club 09/2006 - out of CCR 04/29/08 - XL228 Trial/ U.of Michigan 06/02/08 - CCR ( in 4 weeks) From: Bob <bob-stewart@...> Subject: [ ] PCRU " -The New Group " < >, " CML-Asian Support " <AsianCMLSupportGroup >, " CML-Google Hope Group " <CMLHopegooglegroups> Date: Thursday, October 16, 2008, 10:25 AM Hi folks, Just got my latest (10/1/08) Quant. PCR back--I'm still PCRU. YEAH!!!!!!!! !!!!!!!! Bob , Granger, Indiana Zavie Club # 54 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2008 Report Share Posted October 16, 2008 Go celebrate in the punkin patch! Congratulations, Bob! Loewenkamp [ ] PCRU Hi folks, Just got my latest (10/1/08) Quant. PCR back--I'm still PCRU. YEAH!!!!!!!!!!!!!!!! Bob , Granger, Indiana Zavie Club # 54 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2008 Report Share Posted October 16, 2008 woo hoo good for you what a way to go into another weekend.. Good news apways welcome Big congratulations anita [ ] PCRU Hi folks, Just got my latest (10/1/08) Quant. PCR back--I'm still PCRU. YEAH!!!!!!!! !!!!!!!! Bob , Granger, Indiana Zavie Club # 54 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2008 Report Share Posted October 16, 2008 Congrats !!!!! Eva From: Bob Sent: Thursday, October 16, 2008 10:25 AM -The New Group ; CML-Asian Support ; CML-Google Hope Group Subject: [ ] PCRU Hi folks, Just got my latest (10/1/08) Quant. PCR back--I'm still PCRU. YEAH!!!!!!!!!!!!!!!! Bob , Granger, Indiana Zavie Club # 54 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2008 Report Share Posted October 17, 2008 Great news Kay I,m going on 3 years real close not there yet. ________________________________ From: Quote Link to comment Share on other sites More sharing options...
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