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Re: Stem Cell Harvest

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Donna, you know, with the warming we are getting here, I wonder if it is

related? Like a change of seasons. I noticed last weekend working outside I

felt rather warm all over, but not what you are feeling, just not cool or cold.

chris

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I have had a stem cell harvest but I don't really know about having one

obtained from a sibling. Maybe Tracey would know the answer to this one. I

know that there is a lot of research being done on stem cell. etc.....

I always feel extreme warmth on my skin as well as if anything touches my

skin I get red and blotchy. It could be a band aid, lotion. warm/hot water in

the shower, an article of clothing. My skin is super sensitive since

diagnoses. That goes along with my sensitive scalp. If I wear a headband,

barrette

or a pony tail, I pay for it later.

Oh the funny things we must deal with................

Hugs and Hope-

35

CML 5/13/05

Gleevec 800mg until 8/07

Spyrcel 100 mg since 9/07

Wife and mother of 3 (12,9,7)

# 907 in Zavie's Zero Club

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Hi Donna,

I had something feeling like sunburn when I started gleevec. I was

also very intolerant to warmth for a few days, just getting a blanket

would make me feel queasy. It didn't last long.

Marcos.

On Thu, Mar 20, 2008 at 12:29 PM, donnaberry99 <no_reply > wrote:

>

>

>

>

> I have a question.

> If you can have your own stem cells harvested could a possible donor

> have this done???? The reason I ask is my Brother, a perfect HLA match

> to me is 60 and I worry he could not be available if I need him????? if

> you know what I mean.....

> regards,

> Donna

> PS My body still feels like it is sunburnt but as nobody has said they

> have had this I am thinking it is NOT CML related????

>

>

--

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650 614 2305

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www.stanford.edu/~marcospg/

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Hi Donna,

I think that would depend on your insurance company and if they wanted

to pay for the harvest.

I remember a similar case many years ago and the insurance company said

no to the harvest because they rationed that should the patient ever

need a transplant, the sibling isn't the only way to go so there was no

need to harvest the sibling in a " just in case " scenario. My

suggestion though is that you check with your insurance company.

Tracey

>

> I have a question.

> If you can have your own stem cells harvested could a possible donor

> have this done???? The reason I ask is my Brother, a perfect HLA

match

> to me is 60 and I worry he could not be available if I need him?????

if

> you know what I mean.....

> regards,

> Donna

> PS My body still feels like it is sunburnt but as nobody has said

they

> have had this I am thinking it is NOT CML related????

>

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Tracey makes a good point.

To answer your question, YES it CAN be done. Whether the insurance

company agrees though....

Sibling donors have cells typically collected just a few days before

the transplant and the cells are infused " fresh " . This requires

careful planning as the intended recipient of those cells has already

undergone the myeloablative chemotherpy to prepare for the transplant.

This cannot be done for an autologous situation since the cells

remain fresh for only about 2 days in a refrigerator before they

begin to all die. Not enought time for the chemotherapy remainiing

in the body to completely de-toxify before the infusion and the cells

would just die.

So Autologous cells are " cyropreserved " in liquid nitrogen. Quite

easy nowadays. This can be done for the allogeneic sibling donors as

well. For some reason its usually not but it can be done.

We did it in our lab once. The reason was there was evidently such

bad blood between siblings that eventhough one agreed to donate,

there was a fear the donor would renege at the last moment and leave

the recipient with no active bone marrow. Happy ending though.

Two ways to go. Simple marrow collection or peripheral blood

apheresis collection (1-2 days). The latter needs the donor to take

Neupogen for several days to get the cells " mobilized " into the blood

were they can be collected. Both cost about the same. I recall this

could run in the %5000 to %10,000 range. That's why insurance

approval is important.

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60 is todays 40!!!

WISH I WAS ON KAUAI!!!!!

[ ] Stem Cell Harvest

I have a question.

If you can have your own stem cells harvested could a possible donor

have this done???? The reason I ask is my Brother, a perfect HLA match

to me is 60 and I worry he could not be available if I need him????? if

you know what I mean.....

regards,

Donna

PS My body still feels like it is sunburnt but as nobody has said they

have had this I am thinking it is NOT CML related????

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