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> I was doing some reading and came across this and was wondering if

> anyone has heard or tried the idea of the leptin diet? It seems to

> make more sense than a lot of the diabetic smooze I have heard of

> recent years....esp the avandia.....Thank You Jesus, Hubby decided

> that Avandia was not a good idea. :-) But with several of us in

the

> family having weight issues....it is very interesting.

> thanks

> Ronni

At IMFAR this spring, a group of researchers presented on elevated

leptin levels in some children with autism.

Plasma Leptin Levels are Elevated in Autism:

Association with Early Onset Phenotype?

P. Ashwood, C. Kwong, I. Hertz-Picciotto, P. Krakowiak, R. Hansen, L.

A. Croen, I. N. Pessah, J. Van de Water

J Autism Dev Disord 2007

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=17347881

http://web.mit.edu/autism/leptin%20in%20autism.pdf

The group's Brief Report states:

" [C]hildren with early onset autism had significantly higher plasma

leptin levels compared with children with regressive autism. "

I e-mailed questions to the study's primary author, Dr. Judy Van de

Water. Here are some of her quotes:

" The implications of this study deal more with the role of leptin as

an immune modulator.... While our findings on leptin are interesting,

they are, in fact, part of a larger constellation of changes in

immune function that we have noted in these children.

" While leptin has dual roles, a long-term elevation may have two

effects. One, it would act as an appetite suppressant, as I am sure

you already know. The second effect is more germane to our area of

research which is an increase in inflammatory cytokine production.

" Interestingly, the children with high leptin levels had, if

anything, a lower BMI (body mass index) than the control group. "

Also, a 2005 study by Vargas et al. noted that leptin levels were

elevated in inflamed brain tissue of subjects who had an autism

diagnosis pre-mortem.

- Hokkanen

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Just a helpful suggestion, taking chromium with every meal is useful

for diabetic and hypoglycemic issues. As is cinnamon.

Eating complex carbs with protein, and eating small amounts every

three hours.

>

> I was doing some reading and came across this and was wondering if

> anyone has heard or tried the idea of the leptin diet? It seems

to

> make more sense than a lot of the diabetic smooze I have heard of

> recent years....esp the avandia.....Thank You Jesus, Hubby decided

that

> Avandia was not a good idea. :-) But with several of us in the

family

> having weight issues....it is very interesting.

>

> thanks

> Ronni

>

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  • 6 months later...

A hormone that has a central role in fat metabolism. Leptin was originally thought to be a signal to lose weight but it may, instead, be a signal to the brain that there is fat on the body. Sophia is already gone though...SV <shavig@...> wrote: What is leptin? Shari Suzi List Owner health/ http://360./suziesgoats What is a weed? A plant whose virtues have not yet been discovered.

Looking for last minute shopping deals? Find them fast with Search.

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  • 9 months later...

>

> Diabetic, overweight, low energy-fatigured alot!! Some of the Leptin

> info sounded interesting....

Leptin resistance is NO fun. After giving birth in 2005, I nursed for

8 months, didn't lose an ounce. Once I stopped nursing, I gained.

Then gained more. Then gained even more until I finally figured out

I/we couldn't eat sugar/white crap any longer. Like - at all - not

even in moderation. That meant no more eating out and preparing every

single solitary meal we ate. Diabetics and those borderline, insulin

and leptin resistant people, in my opinion, have no threshold for

moderation. Moderation is for people who are healthy and have healthy

insulin and hormone responses.

It was February of this year I changed our diet and stopped gaining.

We cut everything white, store bought breads, switched to low

pesticide foods, grass fed meats, coconut oil, raw dairy (from a farm

where I know what they feed the cow and chickens). I stopped gaining,

but then I found I could not LOSE. No matter what I did. I read

several books, including " Mastering Leptin " by Byron s. The

book does not really explain a significant differences between leptin

and insulin resistance (perhaps I glazed over during that part), just

that they go hand in hand. Mention was made that if you fix one, you

fix the other. So, I set out to fix one of them if not both. That

was around mid October.

Mastering Leptin talks about five specific things you can do to

reverse leptin resistance.

Never eat after dinner.

Allow 5-6 hours between meals.

Don't eat huge meals, but eat enough (and some fats) to get you to the

next meal.

Eat protein in your breakfast.

Reduce carbs.

Those things make much more sense when you read about them in the book

- which I would highly recommend to anyone trying to fix leptin

resistance. The only thing I found distasteful about the book is that

it is older, there is newer science since then and they guy is a fat

phobe. We need good fats to sustain us between meals - otherwise none

of those things are achievable.

I put those things in practice over the last six weeks, first by

cutting all grains and not eating between meals and after dinner. My

energy increased bucketloads just by doing that. Then I cut carbs

down to <20/day. It took me two weeks to lose 5lbs. But, that was

the first five pounds I'd lost in months and I did it while eating

tons of raw butter, cream, coconut oil and nice fat grass-fed meats.

At times my fat/protein/carb ratio was 65/25/10 - and I track it all

on sparkpeople.com

If your body is healthy enough to do ketosis (burning ketones for fuel

instead of glucose) then you can lose weight this way - and reset

leptin/insulin. I'm sure I don't have to explain the dangers of

ketoacidosis.

It's important to note, that successful weight loss (to me) happens

with you burn your abnormal fat stores (or white fat) and not the

necessary fat and muscle your body needs to survive and have shape.

The only way I know how to do that is to go into ketosis - some would

argue you don't need to be " in ketosis " to burn fat. And as far

as I can tell, this is what body builders set out to do - except, on

top of burning fat, they want to build muscle mass.

The next book on my list - " Good Calories, Bad Calories, " by

Taubes. Ladies, is he yummy or WHAT?! He talks about how carbs, bad

grains and rancid oils have made us fat and miserable for decades -

that exercise doesn't make us lose weight, it makes us HUNGRY!

-vanessa

.... search for Taubes on You Tube

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Hahaha....enjoyed your email!

Yeah, I really need to check out Taubes it sounds like. Seriously and LOL

too ;)

Agreeing with everything you said here, ftmp. I reallyt hink I have

something going on like what you brought up.(insulin/leptin connection and

all) I am so upset that I got my body into this mess somehow, but I

definitely need to find a way out of it, so I¹m determined. One way or the

other!

The stuff you wrote to eat totally cracked me up! LOL (but , if it will help

me lose weight, those are definitely foods I can myself getting down with

okay....minus the bacon....which I used to like just fine, but can¹t seem to

do anymore)

I¹m just getting to the sample menus portion of the n book. So far so

good, looking doable. (of course I¹m reading the low carb week right now,

part of the initial 3 weeks), but when I read the last few pages up to that,

he mentioned fruit for mixing it up and I could make myself do that I¹m

sure....

So I¹m anxious to finish reading the menus and amking some of my own....

And it should be easy to incorporate my own lifestyle into this plan

too.....like my protein choices are usually all rare steak, tilapia, or

salmon, things of that nature, so when he¹s making suggestions about cooked

chicken breast that I don¹t like, its easy for me to see how I could

substitue rare steak where he¹s using chicken, etc.....

Going to check the website out after I send this. Can¹t wait to check it

out! LOL

Chantelle

On 11/27/08 12:38 PM, " van essa " <vandalsem@...> wrote:

>

>

>

>

>

>> > It¹s called LowCarbHighFat

>

> OK.

>

>> > He says this is what it takes to get Leptin levels high.

>

> And if his theory is right, it could work. Another way it could work

> (and I'm not just saying this because I have a crush on Taubes)

> is that it could just all be insulin related. If you starve yourself

> long enough, the insulin in your muscles and organs get so depleted

> that you have no energy and your metabolism basically creeps back into

> " starvation mode " causing a stall or minimal/no fat burning. If you

> carb-up/binge after a few weeks, sending huge mounts of insulin back

> into muscles and organs, it would make sense that you have more energy

> to pull yourself out of starvation and start burning again.

>

> GT seems to be under the impression that leptin is merely in the

> hormonal downstream of insulin. Once insulin gets resolved, so too do

> all the other hormones, including leptin. Check this out:

>

>

http://www.proteinpower.com/drmike/cardiovascular-disease/gary-taubes-responds>

/

>

> And the only reason I've read that website and know about it is

> because Colpo essentially " called out " GT and Dr. Eades

> because he's a cry-baby, closet fat-phobe, aussie musclehead who

> wants attention. It might've been the drama that's sucked me into

> this whole mess. Mmmknow.

>

> I've also read that leptin and insulin drive each other, but I'm

> having a low potassium moment so I'll have to fish for that later.

>

>> > I have no idea what I would even eat though on a day I could eat

>> > whatever I wanted.

>

> I got two words: Cheese Cake

>

> Then five more: Bacon cheeseburger w/sourleavened bread

>

> And in that order.

>

> -vanessa

>

> ... gobble gobble

>

>

>

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Okay, if I find out anything about that , I¹ll let you know. I have

been interested to take my blood sugar frequently and had bought another

meter, only to discover that the strips for it were incredibly

expensive..... I found my old one, but the strips were out of date. So I¹ve

been curious to measure at different times for along time now, but haven't

had a way to do it....

Chantelle

Ps-in regards to the cramps, there are several things that can cause those.

Not ruling out your idea, but not sure if that would cause cramps even if

your muscles are getting ³eaten away² during sleep.

On 11/27/08 2:03 PM, " melly banagale " <@...> wrote:

>

>

>

> Chantelle,

>

> While you read, could you please find out why one's blood sugar rises during

> sleep? In the Mercola website where he interviewed the guy, it said this

> indicated leptin deficiency and it could be " eating away " the muscles.

> Probably why i have cramps in my sleep?

>

> Thanks.

>

>

>

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Chantelle,

My drug store salesperson told me to get a prescrip from my doctor for those

strips/cards and you get to pay less as it is covered by insurance. I did, my

wheel is $100 a box of 10, and i only now pay $40 as copay. Imagine, if not for

his info, i kept buying at my expense all these time.

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wrote: Diabetics and those borderline, insulin

> and leptin resistant people, in my opinion, have no threshold for

> moderation. Moderation is for people who are healthy and have healthy

insulin and hormone responses.

Just happened to reread this email as I was on my way to do something

else......I think this sentence is very very true.

Chantelle

On 11/25/08 8:12 AM, " van essa " <vandalsem@...> wrote:

>

>

>

>

>> >

>

>> > Diabetic, overweight, low energy-fatigured alot!! Some of the Leptin

>> > info sounded interesting....

>

> Leptin resistance is NO fun. After giving birth in 2005, I nursed for

> 8 months, didn't lose an ounce. Once I stopped nursing, I gained.

> Then gained more. Then gained even more until I finally figured out

> I/we couldn't eat sugar/white crap any longer. Like - at all - not

> even in moderation. That meant no more eating out and preparing every

> single solitary meal we ate. Diabetics and those borderline, insulin

> and leptin resistant people, in my opinion, have no threshold for

> moderation. Moderation is for people who are healthy and have healthy

> insulin and hormone responses.

>

> It was February of this year I changed our diet and stopped gaining.

> We cut everything white, store bought breads, switched to low

> pesticide foods, grass fed meats, coconut oil, raw dairy (from a farm

> where I know what they feed the cow and chickens). I stopped gaining,

> but then I found I could not LOSE. No matter what I did. I read

> several books, including " Mastering Leptin " by Byron s. The

> book does not really explain a significant differences between leptin

> and insulin resistance (perhaps I glazed over during that part), just

> that they go hand in hand. Mention was made that if you fix one, you

> fix the other. So, I set out to fix one of them if not both. That

> was around mid October.

>

> Mastering Leptin talks about five specific things you can do to

> reverse leptin resistance.

>

> Never eat after dinner.

> Allow 5-6 hours between meals.

> Don't eat huge meals, but eat enough (and some fats) to get you to the

> next meal.

> Eat protein in your breakfast.

> Reduce carbs.

>

> Those things make much more sense when you read about them in the book

> - which I would highly recommend to anyone trying to fix leptin

> resistance. The only thing I found distasteful about the book is that

> it is older, there is newer science since then and they guy is a fat

> phobe. We need good fats to sustain us between meals - otherwise none

> of those things are achievable.

>

> I put those things in practice over the last six weeks, first by

> cutting all grains and not eating between meals and after dinner. My

> energy increased bucketloads just by doing that. Then I cut carbs

> down to <20/day. It took me two weeks to lose 5lbs. But, that was

> the first five pounds I'd lost in months and I did it while eating

> tons of raw butter, cream, coconut oil and nice fat grass-fed meats.

> At times my fat/protein/carb ratio was 65/25/10 - and I track it all

> on sparkpeople.com

>

> If your body is healthy enough to do ketosis (burning ketones for fuel

> instead of glucose) then you can lose weight this way - and reset

> leptin/insulin. I'm sure I don't have to explain the dangers of

> ketoacidosis.

>

> It's important to note, that successful weight loss (to me) happens

> with you burn your abnormal fat stores (or white fat) and not the

> necessary fat and muscle your body needs to survive and have shape.

> The only way I know how to do that is to go into ketosis - some would

> argue you don't need to be " in ketosis " to burn fat. And as far

> as I can tell, this is what body builders set out to do - except, on

> top of burning fat, they want to build muscle mass.

>

> The next book on my list - " Good Calories, Bad Calories, " by

> Taubes. Ladies, is he yummy or WHAT?! He talks about how carbs, bad

> grains and rancid oils have made us fat and miserable for decades -

> that exercise doesn't make us lose weight, it makes us HUNGRY!

>

> -vanessa

>

> ... search for Taubes on You Tube

>

>

>

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While I have no scientific proof, it seems to me that folks

with leptin resistance are not able to moderate non-foods either.

I have known some people who can easily moderate habits, while

many cannot. Gambling, marijuana, tobacco, alcohol, porn, rage,

workaholism, etc. This inability to moderate seems to me to be tied

into leptin resistance, rather than the person unable to moderate

having a weak moral character.

I know that before I was diagnosed with diabetes, I tried on

numerous occasions to moderate sugar and bread, but it never worked.

I was very despondent at my inability to moderate. Once I started

eating a very low carb diet, I could stay away from sweets and breads,

but if I had one little bit, I would binge.

After several years of proper diet and supplements, I can now

have a small taste of a food which used to make me binge. Now it does

not trigger the compulsion to binge. I strongly suspect that my

insulin resistance is far less. I also feel leptin resistance is also

far less, but I am far less certain of that.

Alobar

On 12/2/08, Chantelle <bornfrueh@...> wrote:

> wrote: Diabetics and those borderline, insulin

> > and leptin resistant people, in my opinion, have no threshold for

> > moderation. Moderation is for people who are healthy and have healthy

> insulin and hormone responses.

>

> Just happened to reread this email as I was on my way to do something

> else......I think this sentence is very very true.

>

> Chantelle

>

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Hmmm....this is interesting to me. I have no desire for sweets and breads.

But I have eaten bites of birthday cake before, etc. It is too sweet to me

now and I tend to not even WANT any more.

Chantelle

On 12/3/08 2:31 AM, " Alobar " <Alobar@...> wrote:

>

>

>

> While I have no scientific proof, it seems to me that folks

> with leptin resistance are not able to moderate non-foods either.

>

> I have known some people who can easily moderate habits, while

> many cannot. Gambling, marijuana, tobacco, alcohol, porn, rage,

> workaholism, etc. This inability to moderate seems to me to be tied

> into leptin resistance, rather than the person unable to moderate

> having a weak moral character.

>

> I know that before I was diagnosed with diabetes, I tried on

> numerous occasions to moderate sugar and bread, but it never worked.

> I was very despondent at my inability to moderate. Once I started

> eating a very low carb diet, I could stay away from sweets and breads,

> but if I had one little bit, I would binge.

>

> After several years of proper diet and supplements, I can now

> have a small taste of a food which used to make me binge. Now it does

> not trigger the compulsion to binge. I strongly suspect that my

> insulin resistance is far less. I also feel leptin resistance is also

> far less, but I am far less certain of that.

>

> Alobar

>

> On 12/2/08, Chantelle <bornfrueh@... <mailto:bornfrueh%40cox.net> > wrote:

>> > wrote: Diabetics and those borderline, insulin

>>> > > and leptin resistant people, in my opinion, have no threshold for

>>> > > moderation. Moderation is for people who are healthy and have healthy

>> > insulin and hormone responses.

>> >

>> > Just happened to reread this email as I was on my way to do something

>> > else......I think this sentence is very very true.

>> >

>> > Chantelle

>> >

>

>

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