Re: effects of prednisone?

[Guest guest]

In a message dated 1/5/08 9:30:56 AM, shotzie@... writes:

>

> Dr Grim

>

> I ended up in the ER last pm for a ? allergic reaction/angioedema I en

> have past history of angioedema from meds and my own hormones, but no

> attacks in a long time.

>

What drugs etc were you taking? Most likely BP med would be ACE.

> Have had a recent viral illness with otitis,

> did not use antibiotics due to sensitivites, save them for critical

> situations only. Work in a pediatric office so constantly exposed,

> this is my first illness since my surgery over a year ago.

>

> I am post left adrenalectomy( I am post left adrenalectomy(<w

> successful. Only problem has been a slight elevated serum Calcium for

> which I have been worked up and nothing found.

>

> ER did CBC and CMP, I was told all normal and given Prednisone 50 mg

> PO in ER and a script for 50 mg for 4 more days. I was told they don't

> taper dose anymore for short term therapy.

>

> I am so darn drug sensitive and have little trust in physicians after

> my battle to finally diagnose Conn's. I have had prednisone twice in

> the past 20 years, the first time didn't pull out of it very well but I

> didn't know my triggers back then.

>

Exactly what do you mean did not pull out of it very well?

> Second time no problems.

>

> I need another opinion....I also need to find someone familiar with

> immunology, I have seen many allergists and they have been of little

> help, although these occurances are infrequent.

>

> Thank you

>

> (shotzie)

>

If you have GRA then prednisone will lower your BP and increase your K. You

prob don't have this so it is good Rx of short term control of angioedema.

Shell fish? ACE? etc need details of everything you are taking.

Do you handle antiobiotics in office?

>

>

May your pressure be low!

Clarence E. Grim, BS, MS, MD

Senior Consultant to Shared Care Research and Consulting, Inc.

(sharedcareinc.com)

Clinical Professor of Internal Medicine and Epidemiology Med. Col. WI

Clinical Professor of Nursing, Univ. of WI, Milwaukee

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

**************

Start the year off right. Easy ways to stay in shape.

http://body.aol.com/fitness/winter-exercise?NCID=aolcmp00300000002489

[Guest guest]

>

>

> In a message dated 1/5/08 9:30:56 AM, shotzie@... writes:

>

>

> >

> > Dr Grim

> >

> > I ended up in the ER last pm for a ? allergic reaction/angioedema

I en

> > have past history of angioedema from meds and my own hormones,

but no

> > attacks in a long time.

> >

> What drugs etc were you taking? Most likely BP med would be ACE.

>

No routine meds, took Sudafed 60mg BID and Guifenisin 400mg TID Tues

and Wed this week to open up clogged left ear which helped at first

but on Thursday had increased swelling of nose and fullness in ears,

then shakiness and flushing in the afternoon, felt was caused by

Sudafed...bp only 124/76. Took no meds thursday or friday but fri PM

had similar reaction but worse, my usual liquid atarax dose of 5 mg

liquid( no typo, can't tolerate more and it usually stops this)

didn't work, shaking increased, slight facial and pharyngeal swelling,

upset stomach,and nasal swelling increased. BP 185/92, pulse 100

Had tried all BP meds in past...most caused either hives, itching,

rash, some face/hand/feet swelling...even an ARB did this, no doctor

would dare try and ACE with my history. That is why I am so hopeful

the surgery was a cure...It has been for over a year but I know there

are no guarantees in your opinion.

Of note is my mother and sister both had similar angioedema symptoms

but didn't pursue treatment as I did. My mother died at age 69 in

2001 from a Sulfa drug reaction. I don't have all history of their

treatment as we were estranged for many years.

>

> >

>> >Prednisone 50 mg

> > PO in ER and a script for 50 mg for 4 more days. I was told they

don't

> > taper dose anymore for short term therapy.

> >

> > I am so darn drug sensitive and have little trust in physicians

after

> > my battle to finally diagnose Conn's. I have had prednisone twice

in

> > the past 20 years, the first time didn't pull out of it very well

but I

> > didn't know my triggers back then.

> >

> Exactly what do you mean did not pull out of it very well?

>

In 1988 was hospitalized for laryngeal edema for three days, sent

home on oral prednisone, can't remember for how long, I think two

weeks in a tapering dose. When dose tapered and after stopped had

joint and muscle pain, fatigue, and a return of allergy symptoms

including bronchospasm that I had never had before

After months of PCP trying every available antihistamine and I had no

good effect I was sent to an allergist, tested and received

immunotherapy

I also learned how to eat right to avoid all allergens, triggers, use

a Hepa in the bedroom etc. It took over a year to straighten out but

I did and never want to go there again.

> >

> > I need another opinion....I also need to find someone familiar

with

> > immunology, I have seen many allergists and they have been of

little

> > help, although these occurances are infrequent.

> >

> > Thank you

> >

> > (shotzie)

> >

> If you have GRA then prednisone will lower your BP and increase

your K. You

> prob don't have this so it is good Rx of short term control of

angioedema.

>

> Shell fish? ACE? etc need details of everything you are taking.

> Do you handle antiobiotics in office?

Had retesting for allergies (skin tests) April 2006

No food allegy found, but allergic to Birch Beech Oak and Ragweed

Need to avoid certain foods in similar families along with yellow #5

which is related to my NSAID and Aspirin sensitivity. Many of my

reactions are sensitivities rather than true allergies but the result

is about the same..throat tightening, nasal swelling , facial flushing

This time I didn't get the laryngeal edema but have had that several

times in the past.

I have had brief episodes of angioedema while taking no meds around

the time of ovulation, they go away with one dose of atarax or

benadryl and aren't as severe or prolonged as what happened this week

Last time that occured was April 2006 , before surgery. I have had no

episodes since the surgery until now.

Since 1988 have only required an antibiotic twice...Levaquin used

for a puncture wound from a garden tool and for a tooth abscess with

good effect and no side effect BUT we used a 250 dose.

I have found through many years of trial and error that I need less

than a normal dose for as short a time as possible

I had no problems with my surgery The anesthesia dept respected my

list of allergies/sensitivities, I had Fentanyl for one day then just

plain tyelenol for pain control

>

> >

> >

>

>

>

>

>

>

>

> May your pressure be low!

>

> Clarence E. Grim, BS, MS, MD

> Senior Consultant to Shared Care Research and Consulting, Inc.

> (sharedcareinc.com)

> Clinical Professor of Internal Medicine and Epidemiology Med. Col.

WI

> Clinical Professor of Nursing, Univ. of WI, Milwaukee

>

> Specializing in Difficult to Control High Blood Pressure

> and the Physiology and History of Survival During

> Hard Times and Heart Disease today.

>

>

>

> **************

> Start the year off right. Easy ways to stay in shape.

>

> http://body.aol.com/fitness/winter-exercise?

NCID=aolcmp00300000002489

>

>

>

[Guest guest]

>Dr Grim

Just found a facinating article which seems to fit my allergic

reaction symptoms to a T

http://www.ajcn.org/cgi/content/full/85/5/1185

It even lists several medications I was given as blocking DAO enzyme

activity, it describes my reactions perfectly and explains why there

are no positive skin tests.

Pubmed has 105 references to this histamine intolerance and pseudo

allergic reactions.

Explains why what I ate over the holidays contributed to my current

condition and how I have been able to control symptoms for so many

years.

Now to find a physician who will believe it!

(shotzie)

Still not looking forward to stopping the prednisone, symptoms

recurred around 3-330 today again without diet or drug provocation

although not as severe. Took prednisone at 5pm, symptoms improved

around 7-7:30. Had burning, swelling and extreme reddness of hands

and feet this time.

[Guest guest]

I would go to the DASH as then you know exactly what you are eating and can

identify triggers when you deviate or even eat some of the items in the DASH.

It is a trail and error (and keeping detailed records ) procedure.

May your pressure be low!

Clarence E. Grim, BS, MS, MD

Senior Consultant to Shared Care Research and Consulting, Inc.

(sharedcareinc.com)

Clinical Professor of Internal Medicine and Epidemiology Med. Col. WI

Clinical Professor of Nursing, Univ. of WI, Milwaukee

Specializing in Difficult to Control High Blood Pressure

and the Physiology and History of Survival During

Hard Times and Heart Disease today.

**************

Start the year off right. Easy ways to stay in shape.

http://body.aol.com/fitness/winter-exercise?NCID=aolcmp00300000002489

[Guest guest]

In a message dated 1/5/08 3:15:16 PM, shotzie@... writes:

>

>

> >

> >

> > In a message dated 1/5/08 9:30:56 AM, shotzie@... writes:

> >

> >

> > >

> > > Dr Grim

> > >

> > > I ended up in the ER last pm for a ? allergic reaction/angioedema

> I en

> > > have past history of angioedema from meds and my own hormones,

> but no

> > > attacks in a long time.

> > >

> > What drugs etc were you taking? Most likely BP med would be ACE.

> >

>

> No routine meds, took Sudafed 60mg BID and Guifenisin 400mg TID Tues

> and Wed this week to open up clogged left ear which helped at first

> but on Thursday had increased swelling of nose and fullness in ears,

> then shakiness and flushing in the afternoon, felt was caused by

> Sudafed...bp only 124/76.

>

Good bet.

> Took no meds thursday or friday but fri PM

> had similar reaction but worse, my usual liquid atarax dose of 5 mg

> liquid( no typo, can't tolerate more and it usually stops this)

> didn't work, shaking increased, slight facial and pharyngeal swelling,

> upset stomach,and nasal swelling increased. BP 185/92, pulse 100

>

> Had tried all BP meds in past...most caused either hives, itching,

> rash, some face/hand/feet swelling...even an ARB did this, no doctor

> would dare try and ACE with my history. That is why I am so hopeful

> the surgery was a cure...It has been for over a year but I know there

> are no guarantees in your opinion.

>

> Of note is my mother and sister both had similar angioedema symptoms

> but didn't pursue treatment as I did. My mother died at age 69 in

> 2001 from a Sulfa drug reaction. I don't have all history of their

> treatment as we were estranged for many years.

> >

>

> > >

> >> >Prednisone 50 mg

> > > PO in ER and a script for 50 mg for 4 more days. I was told they

> don't

> > > taper dose anymore for short term therapy.

>

> > >

> > > I am so darn drug sensitive and have little trust in physicians

> after

> > > my battle to finally diagnose Conn's. I have had prednisone twice

> in

> > > the past 20 years, the first time didn't pull out of it very well

> but I

> > > didn't know my triggers back then.

> > >

> > Exactly what do you mean did not pull out of it very well?

> >

> In 1988 was hospitalized for laryngeal edema for three days, sent

> home on oral prednisone, can't remember for how long, I think two

> weeks in a tapering dose. When dose tapered and after stopped had

> joint and muscle pain, fatigue, and a return of allergy symptoms

> including bronchospasm that I had never had before

> After months of PCP trying every available antihistamine and I had no

> good effect I was sent to an allergist, tested and received

> immunotherapy

>

WE did not have the tools then we have now/

>

> I also learned how to eat right to avoid all allergens, triggers, use

> a Hepa in the bedroom etc. It took over a year to straighten out but

> I did and never want to go there again.

>

> > >

> > > I need another opinion....I also need to find someone familiar

> with

> > > immunology, I have seen many allergists and they have been of

> little

> > > help, although these occurances are infrequent.

> > >

> > > Thank you

> > >

> > > (shotzie)

> > >

> > If you have GRA then prednisone will lower your BP and increase

> your K. You

> > prob don't have this so it is good Rx of short term control of

> angioedema.

> >

> > Shell fish? ACE? etc need details of everything you are taking.

> > Do you handle antiobiotics in office?

>

> Had retesting for allergies (skin tests) April 2006

> No food allegy found, but allergic to Birch Beech Oak and Ragweed

> Need to avoid certain foods in similar families along with yellow #5

> which is related to my NSAID and Aspirin sensitivity. Many of my

> reactions are sensitivities rather than true allergies but the result

> is about the same..throat tightening, nasal swelling , facial flushing

> This time I didn't get the laryngeal edema but have had that several

> times in the past.

>

> I have had brief episodes of angioedema while taking no meds around

> the time of ovulation, they go away with one dose of atarax or

> benadryl and aren't as severe or prolonged as what happened this week

> Last time that occured was April 2006 , before surgery. I have had no

> episodes since the surgery until now.

>

Did the look at your adrenals when you had surgey?

>

> Since 1988 have only required an antibiotic twice...Levaquin used

> for a puncture wound from a garden tool and for a tooth abscess with

> good effect and no side effect BUT we used a 250 dose.

> I have found through many years of trial and error that I need less

> than a normal dose for as short a time as possible

>

> I had no problems with my surgery The anesthesia dept respected my

> list of allergies/sensitivi list of allergies/sensitivi<wbr>ties, I h

> plain tyelenol for pain control

>

> >

> > >

> > >

> >

> >

> >

> >

> >

> >

> >

> > May your pressure be low!

> >

> > Clarence E. Grim, BS, MS, MD

> > Senior Consultant to Shared Care Research and Consulting, Inc.

> > (sharedcareinc. (sh

> > Clinical Professor of Internal Medicine and Epidemiology Med. Col.

> WI

> > Clinical Professor of Nursing, Univ. of WI, Milwaukee

> >

> > Specializing in Difficult to Control High Blood Pressure

> > and the Physiology and History of Survival During

> > Hard Times and Heart Disease today.

> >

> >

> >

> > ************ *

> > Start the year off right. Easy ways to stay in shape.

> >

> > http://body.http://body.<wbrhttp://body.<wbr

> NCID=aolcmp00300000 NCID=

> >

> >

> >