coconut oil and memory

[Guest guest]

Take a look at this article by a neonatologist whose husband has advanced dementia in his 50's. It is a mind blower. Ann Goldeen

WHAT IF THERE WAS A CURE FOR

ALZHEIMER’S DISEASE AND NO ONE KNEW?

A Case Study by Dr. Newport July 22, 2008

There is a growing epidemic of obesity,

type II diabetes, cardiovascular disease,

and predictions that 15,000,000 people

in the United States alone will have Alzheimer’s

Disease by the year 2050.

In 2001, Dr. L. Veech of the NIH,

and others, published an article entitled, “Ketone

bodies, potential therapeutic uses.”1 In

2003, F. Cahill, Jr. and Veech

authored, “Ketoacids? Good Medicine?”2 and

in 2004, Veech published a review of

the therapeutic implications of ketone bodies.

3 These articles are not found in journals

that the average physician would read, much

less the lay public. Unless you are researching

the topic, it is unlikely that you would

ever randomly come across this information.

My husband Steve, age 58, has had progressive

dementia for at least five years. He

had an MRI in May 2008 showing a diffuse

involutional change of the frontal and parietal

lobes and moderate left-sided and severe

right-sided amygdala and hippocampal atrophy

with no ischemic change, which would

support a clinical diagnosis of Alzheimer’s

Disease. For non-medical people, this means

that he has shrunken areas of the brain.

Many days, often for several days in a row,

he was in a fog; couldn’t find a spoon or remember

how to get water out of the refrigerator.

Some days were not so bad; he almost

seemed like his former self, happy, with his

unique sense of humor, creative, full of ideas.

One day I would ask if a certain call came that

I was expecting and he would say, “No.” Two

days later he would remember the message

from so-and-so from a couple of days earlier

and what they said. Strange to have no short-

term memory and yet the information was

filed somewhere in his brain. My gut feeling

is that diet has something to do with the fluctuation,

but what. I knew that he was locked

up in there somewhere, if only there was a

key to open up the areas of his brain that he

didn’t have access to.

Steve has a BSBA in accounting, and did

billing, bookkeeping and accounting for my

neonatology practice from home, so that he

could stay with our girls. He loved computers

and was a fast typist. He could open computers

up to repair them and fix practically anything

else without ever having instruction.

If he did not have a tool to do something he

would “invent” it and make a usable prototype.

He loved to kayak and made an attachment

to keep his kayak moving in a straight

line. About five years ago he began to have

trouble organizing to do his accounting work.

He would procrastinate as much as possible.

He made mistakes with the payroll and I began

to sit with him to help him get it right. I

thought it was just that our practice had gotten

more complicated with more employees. He

knew that something was wrong and depression

set in. We took him to a neurologist about 4 years

ago, who did a Mini Mental Status Exam (MMSE,)

and Steve scored a 23 out of 30, putting him into

the mild range of dementia. On this test, the lower

the score is, the worse the dementia. His MRI was

reported as normal at that time.

About three years ago, Steve started taking

Aricept and two years ago Namenda. We were

hopeful that, if we could slow his decline enough, a

treatment would come along that would turn things

around for him. He was changed over from Aricept to

Exelon in August 2007 after losing ten pounds

over several weeks. In the past 12 months there

was a noticeable change. He can no longer cook

for himself, remember to eat a good meal, use a

calculator or even perform the simplest addition,

however he still keeps busy all day working in the

yard or in his garage and he is still in good physical

condition. I now do all the cooking for a man who

used to cook for his family regularly. I give him the

medications because he can’t remember to take

them, much less take the right pills. Every night,

we hold each other before we go to sleep and I wonder

how many more times we will get to do this. It

has been a nightmare to watch his decline and feel

helpless to do anything but watch it happen. He is

fully aware of his dementia, and we talk about it frequently.

He is no longer depressed, probably with

the help of counseling, Lexipro and Wellbutrin, or

maybe worsening of his disease.

I subscribe to various alerts and check the

website www.clinicaltrials.gov periodically to look

for drug studies that he may qualify for. Two years

ago we tried to get him into a study for a promising

anti-inflammatory drug, Flurizan, but he did

not qualify because he had a history of depression

within the previous two years. Wouldn’t you be depressed

if you knew you had Alzheimer’s? In fact,

depression may be a symptom or precursor of Alzheimer’s.

Until very recently, I didn’t see anything regarding

the potential use of medium chain triglycerides

(MCT oil), or ketone bodies (also called

ketoacids,) the end product of their metabolism,

which may not only treat, but also prevent Alzheimer’s

disease. Further, this is a potential treatment

for Parkinson’s disease, Huntington’s disease,

multiple sclerosis and amyotrophic lateral sclerosis

(ALS or Lou Gehrig’s disease), drug resistant

epilepsy, brittle type I diabetes, and diabetes type

II, where there is insulin resistance. Ketone bodies

may help the brain recover after a loss of oxygen in

newborns through adults, may help the heart recover

after an acute attack, and may shrink cancerous

tumors. Children with drug resistant epilepsy

sometimes respond to an extremely low carbohydrate

ketogenic diet. MCT oil appears to be useful

as an aid in weight loss and body builders use it

already to improve their lean body mass (MCT oil

can be easily purchased on the internet.) Athletes

and soldiers could use MCT oil as a source of fuel

when the body runs out of carbohydrates, which

occurs rather quickly when food is not readily

available.

What do these entities have in common? Our

cells can use ketone bodies as an alternative fuel

when glucose is not available. Brain cells, specifically

neurons, are very limited, more limited than

other cells, in what kinds of fuel they can use to

function and to stay alive. Normally, they require

glucose (sugar), but they can also use ketone bodies.

Humans do not normally have ketone bodies

circulating and available to the brain unless they

have been starving for a couple of days or longer,

or are consuming a ketogenic (very low carbohydrate)

diet, such as Atkins. In Alzheimer’s disease,

the neurons in certain areas of the brain are unable

to take in glucose4, 5 due to insulin resistance

and slowly die off, a process that appears to happen

one or more decades before the symptoms become

apparent. If these cells had access to ketone bodies,

they could potentially stay alive and continue

to function. It appears that persons with Parkinson’s

disease,6 Huntington’s disease, 7 multiple

and ALS9 have a similar defect in utilizing glucose

but in different areas of the brain or spinal cord.

MCT oil is digested differently by the body

than other fats. Instead of storing all MCTs as fat,

the liver converts them directly to ketone bodies,

which are then available for use as energy. Oral

and intravenous administration of MCT oil produces

hyperketonemia, 10 or circulating ketone bodies,

which are then available to the brain for energy, in

the absence of glucose19 and even in the presence

of glucose.22 In addition, hyperketonemia results in

a substantial (39%) increase in cerebral blood flow,

18 and appears to reduce cognitive dysfunction associated

with systemic hypoglycemia in normal

humans. 19

About 2 months ago, we took Steve to the

ny B. Byrd, Jr. Alzheimer’s Institute at University

of South Florida (USF) in Tampa, Florida

for an annual evaluation and screening for a vaccine

study (Elan.) He was fasting for blood work

and had an MMSE of 12, much too low to qualify

for the vaccine study – a minimum score of 16 was

required. We were very disappointed, but were advised

that we could come back another time to try

again, since he met all of the other criteria.

We made an appointment in mid-May 2008 in

St. sburg, Florida to screen Steve for an Eli

Lilly gamma-secretase inhibitor and made another

appointment for Steve to be screened for entry

into the Elan study at USF the following day. The

evening before the first screening in St. Pete, I researched

the two drugs to help us decide which

drug to choose, should he qualify for both studies.

I came across another drug, Ketasyn, or AC-1202,

that was also recruiting healthy older people to

test the tolerability of three different formulations.

Investigating further, I learned that this treatment

brought about significant improvement over a 90-

day period in about half of the subjects who had a

certain genetic profile (APOE2 or APOE3.) The

APOE4 group remained about the same, whereas

the controls (people taking the placebo) continued

to show decline. The results were even more

impressive for people who were already taking

certain Alzheimer’s medications. In a pilot study,

some people improved on memory testing with the

very first dose. Upon doing an internet search for

Ketasyn, I found a January 2008 patent application

(see www.freepatentsonline.com ,)10 a continuation

of a 2000 application, 75 pages long, with a well-

written and thorough description of the science of

Alzheimer’s disease and description of the “invention,”

including these study results and numerous

potential formulations in combination with other

substances that may enhance its effect.

I learned that the promising “ingredient” in

Ketasyn is simply MCT oil, and that a dose of 20

grams (about 20 ml or 4 teaspoons) was used to

produce these results. The MCT oil that these researchers

used was obtained from Stepan Company

and consists of primarily 6 and 8 carbon chains,

however they state that MCT of any combination of

medium chains (6 to 12 carbon chains are medium

chain) would also be effective. Just once in this application,

the author mentions that MCT oil is derived

from coconut or palm oil (this is incorrect,

the author should have stated palm kernel oil.)

I didn’t know at that point that I could easily

purchase MCT oil online, so I researched coconut

oil and found out that coconut oil is about 60% medium

chain fatty acids (MCFA), contains no cholesterol

and also contains omega-6 fatty acids and

some other short and long chain fatty acids of up

to 18 carbon chains. 11 Coconut oil can be found in

many health food stores and even some grocery

stores. Wal-Mart sells a non-hydrogenated (no

transfat) brand of coconut oil in a one-liter size

(almost 32 ounce containers) for about $7 in our

area of Florida. It can be purchased in quantities

as small as a pint and up to five gallons online. It is

important to use coconut oil that is non-hydrogenated

and contains no transfat. There is a widely

held misconception that coconut oil is the “artery

clogging oil,” a term coined in the mid-1900’s by

the president of Proctor and Gamble, the manufacturer

of Crisco and other hydrogenated vegetable

oils. The early studies in animals used hydrogenated

coconut oil, which we now know produces the

notorious trans-fats, and the essential fatty acids

were excluded from the diet. 13

The largest producer of coconut oil is the Philippines,

where coconut and its oil are food staples,

and it is also produced in India, Thailand and other

parts of Southeast Asia, the Caribbean islands and

even in south Florida. The Philippines has one of

the lowest incidences of cardiovascular disease in

the world. Studies have shown that total cholesterol

to HDL ratio improves with non-hydrogenated

coconut oil.14, 15, 16, 17 The people in this part of the

world also eat fish regularly, providing them with

omega-3 fatty acids, which probably contributes as

well to the lack of cardiovascular disease. My nurse

friends from the Philippines tell me that many of

their relatives back home cook everything in coconut

oil and have coconut in one form or another at

nearly every meal.

I have also learned that after coconut and palm

kernel oil, the food that medium chain triglycerides

are most concentrated in is human breast milk. 12 It

is also found in smaller concentrations in goat and

cow’s milk, as well as the butters from these milks.

In fact, we used to add MCT oil 20-25 years ago to

premature formulas to add calories, and MCT, coconut

and palm oils are currently added to premature

and full term infant formulas, along with ARA

and DHA to mimic breast milk.

Back to Steve, it was too late to find coconut

oil before the first screening. On the way, I reminded

him repeatedly that we were in St. sburg,

in Pinellas County. On the MMSE, he remembered

the city but not the county, and he couldn’t remember

the season, the month or day of the week,

much less the date, even though he had to initial

and date numerous pages of consent forms before

the MMSE. He had to be reminded on every

single page where to initial and what the date was

and even how to write out the date. He scored a

14, too low for entry into the study. Dr. Margarita

Nunez spent considerable time with us and asked

Steve to draw a clock (see clock #1), which she

said was a specific test for Alzheimer’s. She took

me aside and told me that his “clock” indicated he

was leaning more towards severe than moderate

AD, a devastating, but not surprising revelation to

me, considering that I am his wife of 36 years and

now his caretaker.

Thinking, what have we got to lose, we stopped

at a health food store on the way home and picked

up a quart of 100% “virgin” coconut oil. I calculated

that in order to provide 20 gm of MCT, he would

need to take 35 grams or just over two tablespoons

(about 35 ml or 7 level teaspoons) of

coconut oil. The following morning, around

9 A.M., I made oatmeal for breakfast and

stirred two tablespoons, plus more for “good

luck,” into his portion. I had some as well,

since I cannot expect him to eat something

that I won’t eat.

On the way to the 1:00 P.M. screening,

I tried to prepare Steve by asking him the

season, the month, the day of the week, reminding

him that we were going to Tampa,

in Hillsborough county. He couldn’t remember

the word “spring,” came up with April

instead of May for the month every time I

asked him and he couldn’t remember it was

Wednesday. During the hour-long drive, we

went through these facts at least 10 times,

but he still couldn’t remember. Shortly after

we arrived he was whisked away for the test,

about 4 ½ hours after consuming the coconut

oil. When he returned, he was very unhappy

about his performance. , the research

coordinator, returned shortly thereafter and

began to take his vital signs and blood pressure,

and, suspecting that we were continuing

with the screening process, I asked her

if she could share his score with us. She

said, “Didn’t he tell you? He scored an 18!”

more than he needed to qualify for the vaccine

study. He remembered it was spring, it

was May, it was Wednesday, that he was in

Tampa, in Hillsborough county and that we

were at the Byrd Institute, all points that he

missed on the previous attempt at USF. As a

result of the screening, we learned that he is

positive for APOE4, but do not know at this

time if he has one or two copies.

According to the Ketasyn studies, Steve

should not have improved, but rather he

should have stayed about the same. Since then

he has retested for the Eli Lilly study drug,

now available closer to home and scored an

MMSE of 17 - he even remembered the date

of July 2, 2008 this time. We have decided, after

looking at the potential side effects of the

vaccine for APOE4+ people, to go with the Eli

Lilly drug.

At the time of this writing it has been

60 days since he started taking coconut oil

(May 21, 2008.) He walks into the kitchen

every morning alert and happy, talkative,

making jokes. His gait is still a little weird.

His tremor is no longer very noticeable. He is

able to concentrate on things that he wants to

do around the house and in the yard and stay

on task, whereas before coconut oil he was

easily distractible and rarely accomplished

anything unless I supervised him directly, a

source of some contention between us!

After about two weeks, and again at 37

days, after starting the coconut oil, I asked

him to draw a clock (see Clocks #2 and #3.)

There is an obvious marked improvement. I

promise that I did not help him. He tells me

that he could not even picture a clock at the

St. Pete screening, but with the last two attempts,

he was very concerned that the 6 was

opposite the 12 and the 9 opposite the 3 on

the face of the clock. He drew “spokes” to

help them line up. I did not ask him to try to

put in a time, the next part of that test.

Steve has not been able to type for at least

two years, but he feels that he can picture

the position of the letters on the keyboard.

At this point he is afraid to sit down and try

to type, worried that he will be discouraged

if it doesn’t come back right away. We are

considering trying occupational therapy to

see if he can relearn some of the skills he has

lost. I cannot explain why he has improved,

except that perhaps the 10 and 12 carbon

chains are important, or the APOE4 people in the

Ketasyn studies were not taking omega-3 fatty acids.

We eat salmon at least twice a week and take

fish oil supplements twice a day and have for at

least the past two years.

I have been researching on the internet everything

I can find about coconut oil, MCT oil,

fatty acids, ketone bodies, fatty acid composition

of breast milk, ketones and various disease states.

When I researched ketone bodies, I came across

the name of Dr. Veech of the National

Institutes of Health. I contacted him to ask questions

about all of this and he very kindly spoke with

me and emailed me articles he had written on the

subject. I have had numerous questions and ideas,

and he has continued to provide me with answers

and more papers to read. I am thinking not only

about people with neurodegenerative diseases

like my husband, but also the sick and premature

newborns that I take care of, and potential uses

for those at both ends of the spectrum of life and

everyone in between. I wonder about autism and

whether something very important is missing in

infant formulas and in the diets of women who are

breastfeeding. 23

Beta-hydroxybutyrate is the primary ketone

body that is the end product of fatty acid metabolism

and appears to protect neurons when glucose

is not available. 20 Dr. Veech can make an ester

form of beta-hydroxybutyrate in his lab from MCT

oil that can be taken orally and converted to energy

by neurons and other cells. Potentially, higher levels

of ketone bodies could be obtained by ingesting

beta-hydroxybutyrate directly. He has done

studies on animals, but needs to produce this in

quantity to be able to do human studies. He could

start testing this year, if only he had the funding.

He needs $15 million to build a plant to produce

his beta-hydroxybutyrate. That is a lot of money,

but not so much if you consider that it is $1.00 for

every person that is expected to have Alzheimer’s

disease by the year 2050.

We visited Cincinnati at the end of June and all

of my family and Steve’s family noticed a very significant

difference in how he interacted with them

socially compared to a year ago. Instead of looking

lost, he was involved and interested in what they

had to say. He recognized relatives (brothers-in-

law, nieces and nephews) by name immediately

that were unfamiliar to him a year ago. His facial

expression was more animated. He participated

actively in conversations, understood jokes immediately

and even came up with his own humorous

comments. He still had difficulty finding some

words, but he was talking in sentences and even

stringing sentences together. In the morning he

would come to the kitchen and ask me to walk the

“big hill” with him before breakfast to get some exercise.

He is a very different person than he was a

year ago and perhaps even two or three years ago.

He has serious atrophy of his brain and will never

be “normal,” but for now we are very pleased with

where he is at and, should coconut oil stop or slow

down the progress of his disease, it will be worth

every drop that he takes.

My sister Lois told a lady she works with about

the coconut oil and Steve’s response to it. Her father

began to give this to her mother, who has Alzheimer’s

and she has had a similar response, with

more alertness, conversation and sense of humor.

On July 9, 2008, Steve had blood samples

drawn at various times before and following breakfast

and dinner. He received 35 ml of coconut oil at

each of those meals. He did not receive any other

coconut oil or other coconut products during the

rest of that day. Normally, he receives more coconut

oil than that on the average day. Steve’s ketone

body levels began to increase after breakfast over

3 hours, but at relatively low levels, dropped again

before dinner and were steadily rising about 3

hours after dinner. We do not know when his levels

peaked because we did not draw any further levels

thereafter. Dr. Veech stated that it is surprising that

Steve would improve with these relatively low levels

of ketones. This study reaffirms his belief that

it is necessary to go forward with the production

and testing of his ketone body b-hydroxy butyrate

esters, since considerably higher levels of ketone

bodies, timed and controlled could be achieved,

and more ketones would be available for the neurons

to use, and therefore greater improvement

could be expected.

It is urgent that funding become available

to move forward for the sake of the millions

who currently suffer, and will in the future

suffer, from Alzheimer’s disease, Parkinson’s

disease, Huntington’s chorea, multiple sclerosis,

ALS, type I and type II diabetes, as

well as any number of other conditions that

involve a defect in transport of glucose into

neurons and other cells.

Until Dr. Veech’s beta-hydroxybutyrate is tested

and available for use, a simple dietary change to

coconut oil could make a difference for people who

believe they are at risk and for those who already

have one of these diseases.

To duplicate the dose of MCT taken in the

Ketasyn study, about 7 level teaspoons should be

taken at one time, once a day, which should circulate

ketone bodies for about 24 hours. I do not know

if it is necessary to take this much at one time or

if the dosage could be spread out over the course

of the day. Studies obviously need to be done to

determine this. We actually give this amount to

Steve at least twice a day to make sure that there

are no periods without ketone bodies circulating.

Many days he receives at least 50% more than this.

The amounts we are taking would not be excessive

in areas of the world where coconut is a staple. If

a person can tolerate more, or can work up to tolerating

more, it may be a good idea to do so. As an

alternative, one could take 4 teaspoons of MCT oil

once or twice a day, or more often as tolerated.

Some people may experience a sense of

“fullness” or even have diarrhea after taking this

much to start, but this problem can be reduced by

starting with one or two teaspoons and increasing

over a week or so to the full amount. We put it in

oatmeal, combine it with salad dressings, use it to

cook with, and put it on anything that one would

normally put butter on, such as potatoes, sweet potatoes,

rice, pasta or noodles. Coconut ice cream

can be purchased at Asian stores, contains coconut

oil and is the most pleasant way I can think of to

make ketone bodies. Likewise, coconut milk is a

combination of coconut oil and coconut water and

can be found in the Asian and condensed milk sections

of many grocery stores. It is a pleasant substitute

for milk, and can be added instead of milk, for

example, to make scrambled eggs, French toast,

Clock #1 - The day before

starting coconut oil.

Clock #2 - Two weeks after

starting coconut oil.

Clock #3 - Thirty-seven days

after starting coconut oil.

and mashed potatoes. You can figure out portion

sizes of various combinations of foods containing

coconut and coconut oil equivalent to at least 35

grams of fat from coconut oil.

If you are using any type of hydrogenated vegetable

oil or any oil with transfat, do not use any

more and get rid of it! Extra virgin olive oil, butter

and other natural, non-hydrogenated oils are

okay to use along with the coconut oil. It is possible

to use coconut oil in place of all other oils, however,

since it contains no omega-3 fatty acids, it is

very important to eat salmon twice a week or get

enough omega-3 fatty acid from other rich sources

such as fish oil capsules, flax meal, flax oil (not for

cooking) or walnuts.

It is inconceivable that a potential dietary prevention

and cure for Alzheimer’s disease, and other

neurodegenerative diseases, has been out there for

so many years, and yet has gone unnoticed. It is

very likely that these diseases are becoming more

prevalent due our current diet. The American diet

has changed drastically from what it was before the

1950’s, when our parents and grandparents used

lard and coconut oil to cook. Cardiovascular disease

was rare at the beginning of the 20th century,

and has skyrocketed, along with other devastating

diseases, such as Alzheimer’s, diabetes type II, obesity,

since mass produced hydrogenated vegetable

oils containing trans fats were introduced into our

diets and replaced these other natural fats. Sadly,

the incidences of cardiovascular and other serious

diseases are becoming more and more common

among people in other areas of the world who have

changed over from their indigenous foods to the

“western” diet.

I plan to tell everyone I can and get this information

to persons in positions to investigate this

with the hope that Dr. Veech and other MCT oil

and ketone body researchers get the funding they

need. Feel free to make copies and pass this write-

up on.

If you have a loved one or a patient with

Alzheimer’s or one of these other degenerative

neurologic diseases, consider trying coconut oil.

Dr. Veech suggests that, if possible, a videotape of

the person before starting and at various points after

starting the coconut oil would be very useful to

document change. He suggests including segments

of the persons face, speech and gait (walking).

He also advises to have ketone bodies

measured. What have you got to lose?

Dr. Newport

10030 Orchard Way

Spring hill, FL 34608

Home: (352) 666-1025

Cell: (352) 428-0251

Preemiedoctor@...

Coconut oil and MCT oil websites:

www.coconutoilresearch.com

www.nutiva.com • www.amazon.com

www.tropicaltraditions.com

www.oilsbynature.com

www.cheapvitamins.com

Palm kernel oil website:

www.oilsbynature.com

Coconut oil and coconut milk are also available

at most health food stores and many

grocery stores.

References:

1. “Ketone bodies, potential therapeutic uses,” RL Veech, B Chance, Y Kashiwaya,

HA Lardy, GC Cahill, Jr., IUBMB Life, 2001, Vol. 51 No.4, 241-247

2. “Ketoacids? Good Medicine?” F. Cahill, Jr., L. Veech,

Transactions of the American Clinical and Climatological Association,

Vol. 114, 2003.

3. “The therapaeutic implications of ketone bodies: the effects of ketone bodies

in pathological conditions: ketosis, ketogenic diet, redox states, insulin

resistance, and mitochondrial metabolism,” L. Veech, Prostaglandins,

Leukotrienes and Essential Fatty Acids, 70 (2004) 309-319.

4. “Diminished glucose transport and phosphorylation in Alzheimer’s Disease

determined by dynamic FDG-PET,” M Piert, et.al., The Journal of Nuclear

Medicine, Vol.37 No.2, February 1996, 201-208.

5. “Glucose metabolism in early onset versus late onset Alzheimer’s Disease: an

SPM analysis of 120 patients,” EJ Kim, et. al., Brain, 2005,

Vol. 128, 1790-1801.

6. “Cerebral glucose metabolism in Parkinson’s disease with and without

dementia,” RF Peppard, et.al., Archives of Neurology, Vol. 49 No.12,

December 1992.

7. “Cortical and subcortical glucose consumption measured by PET in patients

with Huntington’s disease,” Brain, October 1990, Vol 113, part 5, 1405-23.

8. “Reduced glucose metabolism in the frontal cortex and basal ganglia of

multiple sclerosis patients with fatigue: a 18F-fluorodeoxyglucose positron

emission tomography study,” U Roelcke, et. al., Neurology, 1997, Vol. 48, Issue

6, 1566-1571.

9. “ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and

glutamate transport and exacerbates ischemic brain injury,” Z Guo, et. al.,

Journal of Cerebral Blood Flow Metabolism, March 2000, Vol. 20 No. 3, 463-8.

10. “Combinations of medium chain triglycerides and therapeutic agents for the

treatment and prevention of Alzheimer’s disease and other diseases

resulting from reduced neuronal metabolism,” United States Patent 20080009467,

Inventor T. , Accera, Inc., Broomfield,

Colorado (Ketasyn).

11. Nutrient analysis of coconut oil (vegetable), NDB No: 04047 –

www.nal.usda.gov/fnic/foodcomp .

12. “Lipids in (human) milk and the first steps in their digestion,” M Hamosh,

et. al., Pediatrics, 1985, Vol. 75, 146-150.

13. “Nutritional factors and serum lipid levels,” EH Ahrens, American Journal of

Medicine, 1957, vol. 23, 928 (used hydrogenated coconut oil).

14. “Trans fatty acids and coronary artery disease,” NEJM, 1999, Vol. 340,

1994-1998.

15. “Effect of mixed fat formula feeding on serum cholesterol level in man,” SA

Hashim, American Journal of Clinical Nutrition, 1959, Vol. 7, 30-34.

16. “Modified-fat dietary management of the young male with coronary disease: a

five-year report,” JL Bierenbaum, JAMA, 1967, Vol. 202, 1119-1123.

17. “Cholesterol, coconuts and diet in Polynesian atolls-a natural experiment;

the Pukapuka and Toklau island studies,” IA Prior, American Journal of

Clinical Nutrition, 1981, Vol. 34, 1552-1561.

18. “Changes in cerebral blood flow and carbohydrate metabolism during acute

hyperketonemia,” S.G. Hasselbalch, et.al, Am J Physiol, 1996,

Vol. 270, E746-51.

19. “Effect of hyperketonemia and hyperlacticacidemia on symptoms, cognitive

dysfunction, and counterregulatory hormone responses during hypoglycemia

in normal humans,” T. Veneman, et. al., Diabetes 43:1311-7 (1994).

20. “D-b-Hydroxybutyrate protects neurons in models of Alzheimer’s and

Parkinson’s disease,” Y Kashiwaya, et. al. including RL Veech, PNAS, May 9,

2000, Vol. 97 No. 10, 5440-5444.

21. “High carbohydrate diets and Alzheimer’s disease,” T. ,

Medical Hypotheses, 2004, Vol 62, 689-700 (Another article of interest).

22. “Effects of b-Hydroxybutyrate on cognition in memory-impaired adults,” MA

Reger, ST , et. al., Neurobiology of Aging, 2004,

Vol. 25, 311-314.

23. “Breastfeeding, infant formula supplementation, and Autistic Disorder: the

results of a parent survey,” ST Schultz, et. al., International Breastfeeding

Journal, 2006, Vol. 1 No. 16.

Other Important Resources

“Ketones: Metabolism’s Ugly Duckling,” TB VanItallie, TH Nufert, Nutrition

Reviews, Vol 61, No 10, 327-341.

“Fuel Metabolism in Starvation,” GF Cahill, Jr., Annual Reviews in Nutrition,

2006, 26:1-22.

“Ketone Bodies as a Therapeutic for Alzheimer’s Disease,” ST , Journal

of the American Society for Experimental NeuroTherapeutics,

Vol 5, 470-480, July 2008.

[Guest guest]

tol'dcha!!

Seriously, that is a great article, Ann. Thanks for passing it on.

Coconut or medium chain triglycerids are a necessary component of the human body.... we just need to look at the disease rates with thyroidism and cancers - and yes, any of the mental, neurological diseases - since that marketing blitz from the soybean companies in the 80s to see the validity of that. Once the public 'bought it' that coconut oil would clog their arteries, people have refused to use it. Coconut and palm and palm kernel oils liquify at 76 degrees .... below that it does look like lard but, if you put it on your tongue, it will melt instantly.

Sunny

Sunny Kierstyn, RN DC Fibromyalgia Care Center of Oregon 2677 Willakenzie Road, 7C

Eugene, Oregon, 97401

541- 344- 0509; Fx; 541- 344- 0955

From: anngoldeen@...Date: Thu, 18 Dec 2008 10:36:32 -0800Subject: coconut oil and memory

Take a look at this article by a neonatologist whose husband has advanced dementia in his 50's. It is a mind blower. Ann Goldeen

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[Guest guest]

Yea Sunny it will melt instantly but taste like poop!!! I put in a small bowl melt it and drink it...tastes much better

coconut oil and memory

Take a look at this article by a neonatologist whose husband has advanced dementia in his 50's. It is a mind blower. Ann Goldeen

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so what .... the molecules from the bowl change the flavor??? whateverworks, Charlie!

Sunny ;'-))

Sunny Kierstyn, RN DC Fibromyalgia Care Center of Oregon 2677 Willakenzie Road, 7C

Eugene, Oregon, 97401

541- 344- 0509; Fx; 541- 344- 0955

From: caughlindrc@...To: anngoldeen@...; ; skrndc1@...Subject: Re: coconut oil and memoryDate: Thu, 18 Dec 2008 13:47:27 -0800

Yea Sunny it will melt instantly but taste like poop!!! I put in a small bowl melt it and drink it...tastes much better

coconut oil and memory

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yes they do I have special bowls hahah no its the texture

coconut oil and memory

Take a look at this article by a neonatologist whose husband has advanced dementia in his 50's. It is a mind blower. Ann Goldeen

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Charlie, We have been eating coconut oil for several years and have never had an unpleasant flavor. In fact the flavor varies from intense essence of pure coconut to mild almost tasteless depending on if it is extra virgin or a later pressing. Maybe you got a bad batch.?? Ann Goldeen

coconut oil and memory

Take a look at this article by a neonatologist whose husband has advanced dementia in his 50's. It is a mind blower. Ann Goldeen

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It is extra virgin 2nd press it tastes ok melted. I am going to start puttting it in my bloatmeal

coconut oil and memory

Take a look at this article by a neonatologist whose husband has advanced dementia in his 50's. It is a mind blower. Ann Goldeen

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