Guest guest Posted June 6, 2006 Report Share Posted June 6, 2006 Hair loss can also be a symptom of insulin resistance/polycystic ovary syndrome and/or fatty acid deficiency/imbalance. Have you ruled out these possibilities? Regards, Monika M. Woolsey, MS, RD http://www.afterthediet.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 awww linda,, same thing happened to me and I DID buy two really cool wigs,, but I only wore them when I was out of the house as they were too warm to wear.. My hair thinned out so much that you could see scalp and so I just shaved it off,, but it has grown back and its beautiful now,, it will grow back hon,, I think that cutting it short will help it to look 'thicker'.. and you can use that shampoo that most ppl who are on chemo use, ask your hairdresser,, I can't remember the name of it.. it is designed for ppl who are on tx and it can help minimize the loss... <linda68082@...> wrote: My hair is starting to thin out quite a bit. Can somebody tell me what I have to look forward to? I'm pretty darn vain, but wearing a wig is just not my thing. Jackie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 I think that shampoo is called Nioxxin. > My hair is starting to thin out quite a bit. Can somebody tell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05@...> wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie>Jackie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Your hair will thin quite a bit but I doubt that you will get to the point where you will need a wig . When I was on treatment I lost 8 inches in length and it became so thin you could see through it when I wore it down . Hair Loss My hair is starting to thin out quite a bit. Can somebody tell me what I have to look forward to? I'm pretty darn vain, but wearing a wig is just not my thing. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 10, 2006 Report Share Posted November 10, 2006 I've gone thru the same thing---and I have chick fuzz fine hair to begin with. I was terrified that I would have to wear wigs or scarves too. It first turned to straw, then fell out in clumps. During treatment, take extra Biotin and Zinc. Those are hair builders. Once treatment is over, the hair will start coming back. Mine is right now. It's like an obsession; I check everyday to see what's coming back and I've had horrible hair all my life. Never been able to do a thing with it. Gav ________________________________________________________________________________\ ____ Music Unlimited Access over 1 million songs. http://music./unlimited Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 10, 2006 Report Share Posted November 10, 2006 Hey, at what point did your hair start to thin out? I've been on tx for three weeks now. I have not noticed any hair thinning yet. This was one of my biggest concerns about starting tx... will I lose a bunch of hair? I already have baby fine hair. I'm 30... and quite vain about my looks... (even though I know I shouldn't be.)Jackie on <redjaxjm@...> wrote: THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05 > wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie>Jackie Sponsored Link Degrees online in as fast as 1 Yr - MBA, Bachelor's, Master's, Associate - Click now to apply Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2006 Report Share Posted November 12, 2006 Hi Kerry, Mine started to thin out at about 13 weeks. I had it cut into a short style so it would look fuller and not so thin. That made a big difference. It is still thinning but not nearly as much as before (I am on week 32). Oh, and when it thins, it will thin evenly, not come out in clumps so no worries there in case you might have been wondering. I had a hard time at first because I was so used to nice thick hair but in the end, I decided that my health was more important then how my hair looked everyday. I am rather used to it now but so do look forward to when it grows back. Remember, it is only a temporary thing and not nearly as important as the health of your liver. Good luck and hang in there, Ally On 11/10/06, Kerri Landress <kerrilandress@...> wrote: Hey, at what point did your hair start to thin out? I've been on tx for three weeks now. I have not noticed any hair thinning yet. This was one of my biggest concerns about starting tx... will I lose a bunch of hair? I already have baby fine hair. I'm 30... and quite vain about my looks... (even though I know I shouldn't be.) Jackie on <redjaxjm@...> wrote: THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05@ > wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie> Jackie Sponsored LinkDegrees online in as fast as 1 Yr - MBA, Bachelor's, Master's, Associate - Click now to apply Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2006 Report Share Posted November 12, 2006 Hi Kerry, Mine started to thin out at about 13 weeks. I had it cut into a short style so it would look fuller and not so thin. That made a big difference. It is still thinning but not nearly as much as before (I am on week 32). Oh, and when it thins, it will thin evenly, not come out in clumps so no worries there in case you might have been wondering. I had a hard time at first because I was so used to nice thick hair but in the end, I decided that my health was more important then how my hair looked everyday. I am rather used to it now but so do look forward to when it grows back. Remember, it is only a temporary thing and not nearly as important as the health of your liver. Good luck and hang in there, Ally On 11/10/06, Kerri Landress <kerrilandress@...> wrote: Hey, at what point did your hair start to thin out? I've been on tx for three weeks now. I have not noticed any hair thinning yet. This was one of my biggest concerns about starting tx... will I lose a bunch of hair? I already have baby fine hair. I'm 30... and quite vain about my looks... (even though I know I shouldn't be.) Jackie on <redjaxjm@...> wrote: THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05@ > wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie> Jackie Sponsored LinkDegrees online in as fast as 1 Yr - MBA, Bachelor's, Master's, Associate - Click now to apply Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2006 Report Share Posted November 12, 2006 Thanks for the reply, Ally. I know my tx and my liver are the most important things to worry about... I just wanted to know what to expect. I only have to do 24 wks of tx... I'm type 3a. Good luck to you... sounds like you're nearing to the end. Ally <4thMoon@...> wrote: Hi Kerry, Mine started to thin out at about 13 weeks. I had it cut into a short style so it would look fuller and not so thin. That made a big difference. It is still thinning but not nearly as much as before (I am on week 32). Oh, and when it thins, it will thin evenly, not come out in clumps so no worries there in case you might have been wondering. I had a hard time at first because I was so used to nice thick hair but in the end, I decided that my health was more important then how my hair looked everyday. I am rather used to it now but so do look forward to when it grows back. Remember, it is only a temporary thing and not nearly as important as the health of your liver. Good luck and hang in there, Ally On 11/10/06, Kerri Landress <kerrilandress > wrote: Hey, at what point did your hair start to thin out? I've been on tx for three weeks now. I have not noticed any hair thinning yet. This was one of my biggest concerns about starting tx... will I lose a bunch of hair? I already have baby fine hair. I'm 30... and quite vain about my looks... (even though I know I shouldn't be.) Jackie on <redjaxjm > wrote: THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05> wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie> Jackie Sponsored LinkDegrees online in as fast as 1 Yr - MBA, Bachelor's, Master's, Associate - Click now to apply Sponsored Link For just $24.99/mo., Vonage offers unlimited local and long- distance calling. Sign up now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2006 Report Share Posted November 12, 2006 mine started falling out about week 16 or so!Kerri Landress <kerrilandress@...> wrote: Hey, at what point did your hair start to thin out? I've been on tx for three weeks now. I have not noticed any hair thinning yet. This was one of my biggest concerns about starting tx... will I lose a bunch of hair? I already have baby fine hair. I'm 30... and quite vain about my looks... (even though I know I shouldn't be.)Jackie on <redjaxjm > wrote: THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05 > wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie>Jackie Sponsored LinkDegrees online in as fast as 1 Yr - MBA, Bachelor's, Master's, Associate - Click now to apply Jackie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 13, 2006 Report Share Posted November 13, 2006 Mine started dropping at week 14 Re: Re: Hair Loss Hey, at what point did your hair start to thin out? I've been on tx for three weeks now. I have not noticed any hair thinning yet. This was one of my biggest concerns about starting tx... will I lose a bunch of hair? I already have baby fine hair. I'm 30... and quite vain about my looks... (even though I know I shouldn't be.)Jackie on <redjaxjm > wrote: THATS IT!!! thanks ,, Im an old hairdresser too who still has her license,, but I just could NOT come up with the name!!!! thats it and it works <marvindamartian05 > wrote: I think that shampoo is called Nioxxin.> My hair is starting to thin out quite a bit. Can somebodytell me > what I have to look forward to? I'm pretty darn vain, but wearing a > wig is just not my thing. > > > > > > > > > Jackie>Jackie Sponsored LinkDegrees online in as fast as 1 Yr - MBA, Bachelor's, Master's, Associate - Click now to apply Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 I know it does if the disorder is trichtillomania (not sure my spelling is correct). That's compulsive pulling out of the hair which is an OC spectrum disorder. Otherwise, I don't know. --- jan <jkglobal@...> wrote: > The Does hair loss ever > accompany anxiety disorders? Jan > > > [Non-text portions of this message have been > removed] > > ________________________________________________________________________________\ ____ Don't get soaked. Take a quick peak at the forecast with the Search weather shortcut. http://tools.search./shortcuts/#loc_weather Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 I know it does if the disorder is trichtillomania (not sure my spelling is correct). That's compulsive pulling out of the hair which is an OC spectrum disorder. Otherwise, I don't know. --- jan <jkglobal@...> wrote: > The Does hair loss ever > accompany anxiety disorders? Jan > > > [Non-text portions of this message have been > removed] > > ________________________________________________________________________________\ ____ Don't get soaked. Take a quick peak at the forecast with the Search weather shortcut. http://tools.search./shortcuts/#loc_weather Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Hi, I mentioned in another post my oldest daughter's version of anxiety disorder seems to be accompanied by an autoimmune component with flares something like chronic fatigue and/or joint pain, sun sensitivity, RA type symptoms- and one of the first sighs (7th grade-she's now 19) was significant hair loss (jint swelling at same time). Since that time she has not had noticeable hair loss again, but she does sort of go back and forth between skin and hair obsessions and part of her hair obsession is pulling and cutting and recently shaving her head, so whether there is hair loss now is hard to figure out anymore. My mom has an anxious temperament(also had sister who died of lupus) though never seemed to be to clinical degree, and dealt with hair loss all through my childhood, she used to wear a wig when wigs wee more common. nancy grace > > > The Does hair loss ever accompany anxiety disorders? Jan > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Hi, I mentioned in another post my oldest daughter's version of anxiety disorder seems to be accompanied by an autoimmune component with flares something like chronic fatigue and/or joint pain, sun sensitivity, RA type symptoms- and one of the first sighs (7th grade-she's now 19) was significant hair loss (jint swelling at same time). Since that time she has not had noticeable hair loss again, but she does sort of go back and forth between skin and hair obsessions and part of her hair obsession is pulling and cutting and recently shaving her head, so whether there is hair loss now is hard to figure out anymore. My mom has an anxious temperament(also had sister who died of lupus) though never seemed to be to clinical degree, and dealt with hair loss all through my childhood, she used to wear a wig when wigs wee more common. nancy grace > > > The Does hair loss ever accompany anxiety disorders? Jan > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Hi Jan, Hair loss can be caused by anxiety ,as well as many medications used to treat anxiety.(Thyroid problems also) Hugs Judy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Hi Jan, Hair loss can be caused by anxiety ,as well as many medications used to treat anxiety.(Thyroid problems also) Hugs Judy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2007 Report Share Posted July 11, 2007 Hi, Hair loss can occur for many reasons. Stress, poor nutrition, thyroid or medications. I take a teeny amount of lexapro. I first noticed hair loss after starting paxil. It is much less on lexapro, for me. (some might be natural because of my age) My daughter had a terrible reaction to zoloft, (including some hair loss), but is better on prozac. So, meds are something to look at. Although, it is a rare side effect of these meds. Also, had a problem with seroquel. But most people don't. Good luck. Ellen Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2008 Report Share Posted January 24, 2008 Look at iron status, zinc, lysine K. Mackie, MS, RD, LDN Southeast Bariatrics, P.A. 2300-A Randolph Road Charlotte, NC 28207 (704) 347-4144 x 214 hmackie@... www.southeastbariatrics.com From: [mailto: ] On Behalf Of ODonnell Sent: Thursday, January 24, 2008 8:56 AM Subject: hair loss Hi All, I have a patient who is losing a lot of hair. She has been getting adequate protein all along, is there something else that could be causing this? Please advise, thank you O'Donnell RD, LD Never miss a thing. Make your homepage. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2008 Report Share Posted January 24, 2008 I found this article on Web MD: http://www.webmd.com/skin-problems-and-treatments/hair-loss/features/treating-hair-loss-naturally It stressed taking up to 3 mg biotin, high protein (low carb), iron, zinc and omega 3 fatty acids as well as ALA. You might want to read the article and then assess your patient for these nutrients in their diets. Hope this is of some benefit. Kathy J. Shattler, M.S.,RD Director, Nutrition and Dietitians Division Http://www.ceu4u.com kshattler@... "Virtual Continuing Education Institute" hair loss Hi All, I have a patient who is losing a lot of hair. She has been getting adequate protein all along, is there something else that could be causing this? Please advise, thank you O'Donnell RD, LD Never miss a thing. Make your homepage. Never miss a thing. Make your homepage. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2008 Report Share Posted January 24, 2008 How far out is she? Is she RNY or LAP band? How is she getting her protein--from only food, or from food and whey protein shakes? Posted previously: Telogen effluvium (rapid hair shedding) can occur as a result of rapid weight loss. Nutritional deficiencies can contribute to increased hair shedding by weakening hair shafts that cause breakage to the hair and slow regrowth. Principal nutrients that are involved include vitamin A, certain B vitamins, biotin, vitamin C, copper, iron, zinc, and protein--all of which are malabsorbed to some degree by gastric bypass patients. Surgery and anesthesia can also result in temporary hair loss. With time, adequate protein, and vitamin supplements, hair loss will subside. See also Neve, H.J., et al. " Reversal of Hair Loss following Vertical Gastroplasty when Treated with Zinc Sulphate. " Obesity Surgery. 6(1): 63-65. Ava > > Hi All, > I have a patient who is losing a lot of hair. She has been getting adequate protein all along, is there something else that could be causing this? Please advise, thank you > O'Donnell RD, LD > > > > --------------------------------- > Never miss a thing. Make your homepage. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2008 Report Share Posted January 24, 2008 Have you done an Iron panel? > > Hi All, > I have a patient who is losing a lot of hair. She has been getting adequate protein all along, is there something else that could be causing this? Please advise, thank you > O'Donnell RD, LD > > > > --------------------------------- > Never miss a thing. Make your homepage. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 13, 2008 Report Share Posted March 13, 2008 Hi, At 03:31 PM 3/12/2008, you wrote: >I noticed that some morbidly obese patients have very little hair. Is >it due to Polysistic ovary Syn? I can't speak on the PCOS, and I don't know if this could be relevant, but hair loss (and sometimes with loss of hair color) can be a sign of biotin deficiency. Similar issues may occur when something (like oxalate or biotinidase deficiency) produces a loss of function of biotin in carboxylases. Often, there are problems also with yeast infections when biotin function is really impaired. Perhaps this essay by emedicine would be helpful: http://www.emedicine.com/PED/topic238.htm An association with obesity is a bit more obscure, and not too many people have heard of this, but I've put twp examples below to think about and see if it is relevant. Both studies involve some mixed up genetics which predispose rats to having an extra need for biotin to keep from getting fat. There really aren't any human studies that I've found linking biotin deficiency with obesity, except the one below. Even so, some people are trying to develop drugs to treat obesity and metabolic syndrome that kill the function of one of the biotin-dependent enzymes, so this gets complicated.. A lot of the biotin we use comes from our flora which can be killed back by antibiotics. I have a list of which antibiotics kill the biotin producers, if anyone wants to see it and if anyone is interested, I can post the effect that biotin deficiency has on an organic acid test which helps in the diagnosis if you have someone who can read the test for you. Biotin has no known toxicity. I was shocked some years back to find a study talking about a therapeutic dose for dystonia that involved using 5-10 mgs/kg/day and thoroughly turned around the patients' dystonia in a matter of days.. This supplement is often sold in mcgs, but I see it now in health food stores in 5 or 8 mg capsules. In autism circles, our doctors have seen benefits of giving as much as 10 mgs a day to children, but sometimes higher. I wrote a little essay on biotin for the Defeat Autism Now! manual written by Jon Pangborn and Sid Baker: http://autismstore.dyndns.org/Books-Autism_Effective_Biomedical_Treatments.html I'd love to know if any other features of biotin deficiency are present in this patient or in the ones you've seen with hair loss. Biotin status and lipid metabolism in adult obese hypercholesterolemic inbred rats. Marshall MW, Haubrich M, Washington VA, Chang MW, Young CW, Wheeler MA. A statistically significant inverse association was generally found between plasma total lipid, cholesterol, or phospholipid and biotin status of 300-day-old male inbred BHE (IN-BHE) rats. Plasma, liver, and carcass lipid of both sexes generally had a significant direct association with liver lactate dehydrogenase activity; an inverse association in males resulted with improved biotin status. Elevated plasma lactate indicative of anaerobic glycolysis was found. It is proposed that an increased reductive environment - a consequence of accumulated NADH - could account for enhanced triglyceride synthesis and that this effect could explain the obesity in the IN-BHE rats. After the injection of 300 mug of biotin, plasma levels of lactate and pyruvate fell in male rats, indicating a stimulatory effect of biotin upon the oxidative pathways in these animals. PMID: 958648 [PubMed - indexed for MEDLINE] J Nutr Sci Vitaminol (Tokyo). 1996 Dec;42(6):517-26.Links A high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus. Zhang H, Osada K, Maebashi M, Ito M, Komai M, Furukawa Y. Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan. The Otsuka Long- Tokushima Fatty (OLETF) rat, serving as a spontaneously diabetic model with non-insulin-dependent diabetes mellitus (NIDDM), exhibits impaired glucose tolerance (IGT) at about 16 weeks of age. In this study, we investigated whether or not biotin, a water-soluble vitamin, improved the IGT of OLETF rats. To this end, we administered diets containing one of three levels of biotin, a high-biotin diet (BH), a normal-biotin diet (BN) and a basal-biotin diet (BB), to OLETF rats up to 24 weeks of age. An oral glucose tolerance test (OGTT) was performed four times between 13 and 22 weeks of age. The administration of a BH corrected the IGT of OLETF rats. Upon further investigation, we found that insulin secretion in the OLETF-BH rats was decreased to a significant extent, signaling that the hyperinsulinemia typical to the OLETF-BH rats had clearly improved. Body weights were significantly lower in the OLETF-BH group than in the other OLETF groups, even though the OLETF-BH rats showed a significantly higher average daily food intake. The body weight gain of the OLETF-BH rats followed the same tendency as the control-LETO (Long Tokushima Otsuka) rats (LETO-BB and LETO-BN). These results demonstrate that a high-level biotin diet can improve the glucose handicap in NIDDM rats. PMID: 9089478 [PubMed - indexed for MEDLINE] Obes Rev. 2007 May;8(3):253-61.[] Links Epicardial fat: properties, function and relationship to obesity. Rabkin SW. Department of Medicine, Division of Cardiology, University of British Columbia, Vancouver, BC, Canada. rabkin@... Epicardial fat is a relatively neglected component of the heart. The purpose of this review was to examine the anatomic and biochemical data on epicardial fat; to examine the relationship of epicardial fat to obesity and to explore the potential role of epicardial fat in the relationship of obesity to coronary atherothrombotic disease. Epicardial fat covers 80% of the heart's surface and constitutes 20% of total heart weight. It is present along the distribution of the coronary arteries, over the right ventricle especially along the right border, anterior surface and at the apex. There is three- to fourfold more epicardial fat associated with the right than the left ventricle. Putative physiologic functions of epicardial fat are based on observational data and include: buffering coronary arteries against the torsion induced by the arterial pulse wave and cardiac contraction, facilitating coronary artery remodelling, regulating fatty acid homeostasis in the coronary microcirculation and providing fatty acids to cardiac muscle as a local energy source in times of high demand. A considerable amount of the data on epicardial fat originates from autopsy series that have the inherent problem that conditions leading to death may have altered body composition and adiposity. With this caveat, data indicate that epicardial fat mass increases age until age 20-40 years but thereafter the amount of epicardial fat is not dependent on age. The amount of epicardial fat correlates with heart weight but the presence of myocardial ischemia and hypertrophy does not alter the ratio of epicardial fat to cardiac muscle mass. A number of properties differentiate epicardial fat from other fat depots specifically its smaller adipocytes size; different fatty acid composition, high protein content; high rates of fatty acid incorporation, fatty acid synthesis, insulin-induced lipogenesis or fatty acid breakdown; low rates of glucose utilization, low expression (mRNA) of lipoprotein lipase, stearoyl-CoA desaturase and acetyl-CoA carboxylase-alpha, and slow regression during weight loss. There is a significant direct relationship between the amount of epicardial fat and general body adiposity. Clinical imaging studies have demonstrated a strong direct correlation between epicardial fat and abdominal visceral adiposity. Several lines of evidence support a role for epicardial fat in the pathogenesis of coronary artery disease, namely the close anatomic relationship between epicardial fat and coronary arteries; the positive correlation between the amount of epicardial fat and the presence of coronary atherosclerosis and the ability of adipose tissue to secrete hormones and cytokines that modulate coronary artery atherothrombosis. Thus, epicardial fat maybe an important factor responsible for cardiovascular disease in obesity. PMID: 17444966 [PubMed - indexed for MEDLINE] Expert Opin Ther Targets. 2005 Apr;9(2):267-81.[] Links Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition. Harwood HJ Jr. Department of Cardiovascular and Metabolic Diseases, Pfizer Global Research and Development, Groton Laboratories, Pfizer Inc., MS# 820-3190, Eastern Point Road, Groton, CT 06340, USA. h.james.harwood@... Metabolic syndrome is defined as a clustering of cardiovascular risk factors (abdominal obesity, hyperinsulinaemia, atherogenic dislipidaemia, hypertension, hypercoagulability) that together increase the risk of developing coronary heart disease and Type-2 diabetes. Inhibition of acetyl-CoA carboxylase (ACC), with its resultant inhibition of fatty acid synthesis and stimulation of fatty acid oxidation, has the potential to favourably affect, in a concerted manner, a multitude of cardiovascular risk factors associated with metabolic syndrome. Studies in ACC2 knockout mice and in experimental animals treated with isozyme-nonselective ACC inhibitors have demonstrated the potential for treating metabolic syndrome through this modality. A variety of structurally diverse, mechanistically distinct classes of ACC inhibitors have been disclosed in the scientific and patent literature. Isozyme-nonselective ACC inhibitors may provide the optimal therapeutic potential for beneficially affecting metabolic syndrome. However, demonstration of the full potential of isozyme-selective inhibitors, once identified, should reveal advantages and liabilities associated with single isozyme inhibition. Whereas demonstrating clinical efficacy of an ACC inhibitor should be straightforward, the heterogeneity of the patient population and absence of established guidelines regarding approval end points for agents simultaneously affecting multiple aspects of metabolic syndrome will pose developmental challenges for initial market entries. PMID: 15934915 [PubMed - indexed for MEDLINE] J Am Acad Dermatol. 1983 Jul;9(1):97-103.Links Alopecia and periorificial dermatitis in biotin-responsive multiple carboxylase deficiency. ML, Packman S, Cowan MJ. Three siblings with infantile-onset biotin-responsive multiple carboxylase deficiency are described. Recognition of the characteristic dermatologic manifestations, alopecia and periorificial dermatitis, should result in early diagnosis and institution of potentially lifesaving therapy with biotin. Other metabolic disorders may present a similar clinical picture. Immunologic dysfunction and/or aberration in lipid or branched chain amino acid metabolism may be the common pathophysiologic link in some or all of these disorders. PMID: 6886110 [PubMed - indexed for MEDLINE] At 03:31 PM 3/12/2008, you wrote: >I noticed that some morbidly obese patients have very little hair. Is >it due to Polysistic ovary Syn? >Zinc WNL > > -- No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.21.6/1316 - Release Date: 3/6/2008 6:58 PM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2008 Report Share Posted April 7, 2008 , I have heard MTX can cause hair loss. Have you started it recently? allison laptop wrote: Hi all Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot of hair. Especially when I shower and wash my hair or run my hands through my hair. I can run my hands through my hair and easily have 10-20 hairs on my hands. This can happen multiple times in a day. I see my RD on Thursday and plan on talking to him about it, but I thought I d see if anyone else has experienced this problem. Thanks, Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.