Re: Mutations

[Guest guest]

Hi Lottie,

Mutations can happen at any time. Some are more significant than

others and some respond to certain drugs better than others.

They generally don't test for mutations unless there's a reason to.

For example if someone loses their response or if someone isn't

having the desired response after an appropriate amount of time. As

long as a person is doing well, their PCR is stable or continuing

downward, then there's no reason to spend the money on a mutations

test.

Take care,

Tracey

>

> Dear Bobby,

> Isn't V299L the same mutation Len has or had? Do you have the

T315i, or did they test you for it? Jackie took the HHT for her

T315i and it's gone. She's still waiting to get into another trial

now. Does anyone know if you can reach CCR as Bobby did and have a

mutation at the same time and later relapse? I would have thought

they would have done the mutations test a long time ago after none of

the trials worked for you. Do they have to have a special reason for

testing. I asked for one early on, but I don't think it means you

can't develop one down the line. I think some people developed a

mutation while on Gleevec.

> Wishing you all the best, Bobby, it's your turn to return to

CCR. Will Zavie issue you a new number? LOL I suppose in his book

of records, you are still listed with your original number. I want a

nice even number.

> xoxoxoxox

> Lottie

>

>