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Re: Re: TASAGNA AND PANCREAS

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Jean:

I have found that Tasigna is much easier on the intestines

thank Gleevec. In fact, Gleevec gave me daily diarrhea and

Tasigna gives me the opposite. I do take stool softeners.

(fun stuff to write about huh?). I had an initial increase in

pancreatic enzymes, but they subsided after 30 days on

the drug.

I get flush for a few hours right after taking each dose (I take

400 mg, two times a day, 8 hours apart) and I have some

fatigue. In fact, the bone pain, muscle cramping and queasy

stomach all disappeared when I began Tasigna.

I would recommend stool softeners, Gatorade (to balance

electrolytes) and staring on a lower dose and building to

a higher one. They are looking at the efficacy of Tasigna

on a lower maintenance dose for those who reach PCRU.

Good luck.

Matt

In a message dated 5/22/2008 4:38:57 P.M. Eastern Daylight Time,

jmcallister35@... writes:

hi sharon, i am new to the group altho not to CML (9 yrs in 8/08).

never thought i'd live to say that as my 1st dr told me one ususlly

lives only about 4yrs.your post interested me as my dr wants to put

me on tasagna because gleevec is lowing my platelets and making me

anemic plus other annoying side effects.i told her i have had these

problems for almost the whole time i have had CML (9years), but i

think she is being the typical dr, covering all bases, and informing

the patient. which i understand. i am going to get the results of my

latest blood work in about a week, and then we will decide.after i

read you post and saw the reference to the pancreas,now i think i

have another concern lol. i told the dr i wasn't to keen on starting

another high-powered medicine and having another set of side effects

as i have queasy intestines, both large and small.any tips will be

appreciated. thanks jean

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