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Dear Matt,

I couldn't find anything on Wyeth's Basatanib in my searches. The closest

I could find in spelling is Wyeth's Bosutinib which is SKI 606. That is the

drug I am on. There are only about 69 patients in his group world wide. I

don't know why they would say it is not being heavily pursued. Did you attend a

seminar? That must have been very interesting and how lucky that you got to go.

Did they mention any side effects of these drugs?

Blessings and questions,

Lottie

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Lottie:

I did not go to any seminar and I do not profess to be a great speller.

My oncologist is heavy into research and is aware of all the latest

and greatest advancements. Each time I visit him, I try to remember

all the questions that people have posed on this board and take the

time to ask him. At the same time, he updates me on any pertinent

facts regarding medications advancements and research.

For instance, last time I visited him, I took a question to him that

Tracey had regarding T-Cells and Sprycel, to which he candidly

answered " there is some-thing there, but it is too soon to

determine if it a positive or a negative. " Not exactly earth shaking

information.

However, this time we discussed vaccines which had been

mentioned previously. One of the vaccines, he previously

pioneered when he was at Sloan-Ketterling. Then he began

to tell me about third generation drugs, like the Wyeth, which

you said you were on. I believe he said that this one showed

much promise against mutations, but that FDA approval would

more difficult than Sprycel and Tasigna because it was a third

generation drug. Also, the profits for a third generation drug

were not as great, so Wyeth did not seem to be putting the

" full court press " for approval.

Next time I will take the time to record or at least take notes

because some things get lost in the 4 hour drive home. Sorry

about the confusion.

Your Southern Gentleman,

Matt

Florida CML Army

Gleevec

Tasigna

PCRU

In a message dated 5/10/2008 1:42:47 P.M. Eastern Daylight Time,

lotajam@... writes:

Dear Matt,

I couldn't find anything on Wyeth's Basatanib in my searches. The closest I

could find in spelling is Wyeth's Bosutinib which is SKI 606. That is the

drug I am on. There are only about 69 patients in his group world wide. I don't

know why they would say it is not being heavily pursued. Did you attend a

seminar? That must have been very interesting and how lucky that you got to go.

Did they mention any side effects of these drugs?

Blessings and questions,

Lottie

**************Wondering what's for Dinner Tonight? Get new twists on family

favorites at AOL Food.

(http://food.aol.com/dinner-tonight?NCID=aolfod00030000000001)

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