Re: gleevec -- a.m. or p.m.?

[Guest guest]

I take mine at night - I try to wait about 1/2 hour until I lay down. But, I

cannot compare it to taking in the morning. I take it at night to sleep

through the minor nausua it causes. A few times I get sidetracked and don't

go to bed.... I feel crummy. I can't imagine feeling that way all day.

Tammy

_____

From: [mailto: ] On Behalf Of

kathydf47

Sent: Saturday, May 31, 2008 10:56 AM

Subject: [ ] gleevec -- a.m. or p.m.?

Has anyone noticed a difference in fatigue levels during the day by taking

the medication

at night rather than during the daytime?

5 years ago when i was diagnosed, I was told not to take it at bedtime due

to digestive

issues (reflux?) -- but that may be old thinking?

Any other suggestions re fatigue are greatly appreciated.

best to all,

Kathy

dx 5/03

gleevec 400 mg

PCRU

[Guest guest]

the only reason I know for not taking it at bedtime is, you are not supposed to

lie down directly after taking the pills. Maybe an hour or so before? Bobby

kathydf47 <kathydf47@...> wrote: Has anyone noticed a difference

in fatigue levels during the day by taking the medication

at night rather than during the daytime?

5 years ago when i was diagnosed, I was told not to take it at bedtime due to

digestive

issues (reflux?) -- but that may be old thinking?

Any other suggestions re fatigue are greatly appreciated.

best to all,

Kathy

dx 5/03

gleevec 400 mg

PCRU

a (Bobby) Doyle

Brecksville, Ohio, USA

DX 05/1995

02/2000 - Gleevec Trial/OHSU

06/2002 - Gleevec/Trisenox Trial/OHSU

06/2003 - Gleevec/Zarnestra Trial/OHSU

04/2004 - Sprycel Trial/MDACC, CCR in 10 months

#840 - Zavie's Zero Club

09/2006 - out of CCR

04/29/08 - XL228 Trial/ U.of Michigan

[Guest guest]

Hi Kathy,

I've done it both ways. For the first 5 years I took it with supper

and now for the last year or so, I've taken it with breakfast.

I can't say that I've experienced any real difference in terms of the

fatigue or any other side effects though.

The main reason I changed from supper to breakfast was because I

wanted to get it out of the way first thing in the morning and not

have to dread taking it all day long.

I'm much busier in the mornings so when I get the nausea, I'm more

distracted with everything I'm doing (getting the kids out the door,

showering, cleaning up etc) so the nausea seems to be a bit less

severe (I know it's just because I'm more distracted though). At

night, I usually just sit and watch the news after supper so the

nausea was a real focus since I wasn't distracted like I am in the

morning.

They usually don't recommend that you take it right before bed

because if you have gastric reflux, it'll burn your esophagus and

cause you problems.

>

> Has anyone noticed a difference in fatigue levels during the day by

taking the medication

> at night rather than during the daytime?

>

> 5 years ago when i was diagnosed, I was told not to take it at

bedtime due to digestive

> issues (reflux?) -- but that may be old thinking?

>

> Any other suggestions re fatigue are greatly appreciated.

>

> best to all,

> Kathy

> dx 5/03

> gleevec 400 mg

> PCRU

>

[Guest guest]

Hi Kathy,

I used to take it at breakfast (for 2 years) and now I take it at lunch,

because it is more convenient (I often skip breakfast) and lunch is a bigger

meal. Although I think I am getting used to the drug, as I took it several

time out of a meal without getting nauseous. I think we have to be empirical

and try what works for us. Also it may be that the drug is better

assimilated with a bigger and fattier meal, as the improvement of my test

results coincides pretty well with switching to lunch.

Marcos

Dx 2005

400mg gleevec

On Sat, May 31, 2008 at 7:56 AM, kathydf47 <kathydf47@...> wrote:

> Has anyone noticed a difference in fatigue levels during the day by

> taking the medication

> at night rather than during the daytime?

>

> 5 years ago when i was diagnosed, I was told not to take it at bedtime due

> to digestive

> issues (reflux?) -- but that may be old thinking?

>

> Any other suggestions re fatigue are greatly appreciated.

>

> best to all,

> Kathy

> dx 5/03

> gleevec 400 mg

> PCRU

>

>

>

--

Marcos Perreau Guimaraes

Suppes Brain Lab

Ventura Hall - CSLI

Stanford University

220 Panama street

Stanford CA 94305-4101

650 614 2305

650 630 5015 (cell)

marcospg@...

montereyunderwater@...

www.stanford.edu/~marcospg/

[Guest guest]

G'day Kathy,

I don't know about the fatigue bit, bit I certainly am much better taking

mine in the evening with a proper meal as I don't eat enough breakfast.

Regards,

from Downunder

_____

From: [mailto: ] On Behalf Of

kathydf47

Sent: Sunday, 1 June 2008 12:56 AM

Subject: [ ] gleevec -- a.m. or p.m.?

Has anyone noticed a difference in fatigue levels during the day by taking

the medication

at night rather than during the daytime?

5 years ago when i was diagnosed, I was told not to take it at bedtime due

to digestive

issues (reflux?) -- but that may be old thinking?

Any other suggestions re fatigue are greatly appreciated.

best to all,

Kathy

dx 5/03

gleevec 400 mg

PCRU