Guest guest Posted April 9, 2008 Report Share Posted April 9, 2008 The dose of 100 mg has to be in the morning to be considered the " best dose? " I take mine in the evening at bedtime and was wondering if should switch the time.....I am also PCRU. Hugs and Hope- 36 CML 5/13/05 Gleevec 800mg until 8/07 Spyrcel 100 mg since 9/07 Wife and mother of 3 (12,9,7) # 907 in Zavie's Zero Club In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time, seloew12@... writes: Hi Everyone, Some of you may already know this but if you don't here's some news on what is now considered the best dosage of Sprycel. I had my quarterly check-up today (all counts excellent and PCRU). I've been on the trial at the University of loand for more than 2 years and have been PCRU for about a year with very low counts prior to that. I take 100 mg once in the morning daily. That is now considered the best dosage of Sprycel in trials. For those on higher dosages I don't know but for those at 100 mg or less, the best dosage is 100 mg a day once in the morning. People on other dosages and those who take their dosage twice a day instead of once may have their dosages changed on trials because of " safety " issues according to Bristol Meyers Squibb. They don't say exactly what those issues are but I imagine it has to do with side effects such as pleural effusion. I feel fortunate that I've been on what has now proven out to be the best overall dosage and the proof lies in the fact that although I had one bout with pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the symptoms disappeared. Cheerfully, [Non-text portions of this message have been removed] **************Planning your summer road trip? Check out AOL Travel Guides. (http://travel.aol.com/travel-guide/united-states?ncid=aoltrv00030000000016) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 Thanks Sharon and . The time seems to work so I will not " mess with a good thing!!! " Thanks for the input. In a message dated 4/9/2008 10:46:37 P.M. Central Daylight Time, onthewtr@... writes: , I agree with susan. If it works don't break it. Know what I mean? They told me I could take my Tasigna 100mg in the morning and 100mg at night. I have always taken 200mg in the morning and I am doing so well I decided to continue doing 200mg in the morning. Sharon _____ From: _@..._ (mailto: ) [mailto:_@..._ (mailto: ) ] On Behalf Of seloew12 Sent: Wednesday, April 09, 2008 5:38 PM _@..._ (mailto: ) Subject: Re: [ ] Sprycel News Don't know, . If you haven't had side effects and you're PCRU I personally wouldn't worry about it! You're doing great! Cheers, Re: [ ] Sprycel News The dose of 100 mg has to be in the morning to be considered the " best dose? " I take mine in the evening at bedtime and was wondering if should switch the time.....I am also PCRU. Hugs and Hope- 36 CML 5/13/05 Gleevec 800mg until 8/07 Spyrcel 100 mg since 9/07 Wife and mother of 3 (12,9,7) # 907 in Zavie's Zero Club In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time, seloew12cox (DOT) <mailto:seloew12%mailto:se> net writes: Hi Everyone, Some of you may already know this but if you don't here's some news on what is now considered the best dosage of Sprycel. I had my quarterly check-up today (all counts excellent and PCRU). I've been on the trial at the University of loand for more than 2 years and have been PCRU for about a year with very low counts prior to that. I take 100 mg once in the morning daily. That is now considered the best dosage of Sprycel in trials. For those on higher dosages I don't know but for those at 100 mg or less, the best dosage is 100 mg a day once in the morning. People on other dosages and those who take their dosage twice a day instead of once may have their dosages changed on trials because of " safety " issues according to Bristol Meyers Squibb. They don't say exactly what those issues are but I imagine it has to do with side effects such as pleural effusion. I feel fortunate that I've been on what has now proven out to be the best overall dosage and the proof lies in the fact that although I had one bout with pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the symptoms disappeared. Cheerfully, [Non-text portions of this message have been removed] ************************<WBR>**Planning your summer road trip? Check out AO (_http://travel._'>http://travel._ (http://travel./) <_http://travel.http://travel.http://travelhttp://travehttp://travel.<Whttp_ (http://travel.aol.com/travel-guide/united-states?ncid=aoltrv00030000000016) > aol.com/travel-aol.com/traveaol.com/travaol.com/travel-aol.c [Non-text portions of this message have been removed] [Non-text portions of this message have been removed] [Non-text portions of this message have been removed] **************Planning your summer road trip? Check out AOL Travel Guides. (http://travel.aol.com/travel-guide/united-states?ncid=aoltrv00030000000016) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 Don't know, . If you haven't had side effects and you're PCRU I personally wouldn't worry about it! You're doing great! Cheers, Re: [ ] Sprycel News The dose of 100 mg has to be in the morning to be considered the " best dose? " I take mine in the evening at bedtime and was wondering if should switch the time.....I am also PCRU. Hugs and Hope- 36 CML 5/13/05 Gleevec 800mg until 8/07 Spyrcel 100 mg since 9/07 Wife and mother of 3 (12,9,7) # 907 in Zavie's Zero Club In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time, seloew12@... writes: Hi Everyone, Some of you may already know this but if you don't here's some news on what is now considered the best dosage of Sprycel. I had my quarterly check-up today (all counts excellent and PCRU). I've been on the trial at the University of loand for more than 2 years and have been PCRU for about a year with very low counts prior to that. I take 100 mg once in the morning daily. That is now considered the best dosage of Sprycel in trials. For those on higher dosages I don't know but for those at 100 mg or less, the best dosage is 100 mg a day once in the morning. People on other dosages and those who take their dosage twice a day instead of once may have their dosages changed on trials because of " safety " issues according to Bristol Meyers Squibb. They don't say exactly what those issues are but I imagine it has to do with side effects such as pleural effusion. I feel fortunate that I've been on what has now proven out to be the best overall dosage and the proof lies in the fact that although I had one bout with pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the symptoms disappeared. Cheerfully, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 , I agree with susan. If it works don't break it. Know what I mean? They told me I could take my Tasigna 100mg in the morning and 100mg at night. I have always taken 200mg in the morning and I am doing so well I decided to continue doing 200mg in the morning. Sharon _____ From: [mailto: ] On Behalf Of seloew12 Sent: Wednesday, April 09, 2008 5:38 PM Subject: Re: [ ] Sprycel News Don't know, . If you haven't had side effects and you're PCRU I personally wouldn't worry about it! You're doing great! Cheers, Re: [ ] Sprycel News The dose of 100 mg has to be in the morning to be considered the " best dose? " I take mine in the evening at bedtime and was wondering if should switch the time.....I am also PCRU. Hugs and Hope- 36 CML 5/13/05 Gleevec 800mg until 8/07 Spyrcel 100 mg since 9/07 Wife and mother of 3 (12,9,7) # 907 in Zavie's Zero Club In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time, seloew12cox (DOT) <mailto:seloew12%40cox.net> net writes: Hi Everyone, Some of you may already know this but if you don't here's some news on what is now considered the best dosage of Sprycel. I had my quarterly check-up today (all counts excellent and PCRU). I've been on the trial at the University of loand for more than 2 years and have been PCRU for about a year with very low counts prior to that. I take 100 mg once in the morning daily. That is now considered the best dosage of Sprycel in trials. For those on higher dosages I don't know but for those at 100 mg or less, the best dosage is 100 mg a day once in the morning. People on other dosages and those who take their dosage twice a day instead of once may have their dosages changed on trials because of " safety " issues according to Bristol Meyers Squibb. They don't say exactly what those issues are but I imagine it has to do with side effects such as pleural effusion. I feel fortunate that I've been on what has now proven out to be the best overall dosage and the proof lies in the fact that although I had one bout with pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the symptoms disappeared. Cheerfully, Quote Link to comment Share on other sites More sharing options...
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