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Sprycel News

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Hi Everyone,

Some of you may already know this but if you don't here's some news on what is

now considered the best dosage of Sprycel. I had my quarterly check-up today

(all counts excellent and PCRU). I've been on the trial at the University of

loand for more than 2 years and have been PCRU for about a year with very

low counts prior to that.

I take 100 mg once in the morning daily. That is now considered the best dosage

of Sprycel in trials. For those on higher dosages I don't know but for those at

100 mg or less, the best dosage is 100 mg a day once in the morning. People on

other dosages and those who take their dosage twice a day instead of once may

have their dosages changed on trials because of " safety " issues according to

Bristol Meyers Squibb. They don't say exactly what those issues are but I

imagine it has to do with side effects such as pleural effusion.

I feel fortunate that I've been on what has now proven out to be the best

overall dosage and the proof lies in the fact that although I had one bout with

pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the

symptoms disappeared.

Cheerfully,

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