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Re: Re: Rest of the study

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Lottie-

I am waiting to hear the results of the mutation study

and what new meds you are on...did I miss that email?

Chi

--- Barb Stanley <barbarastanley@...> wrote:

>

> Lottie

>

> I agree with Tracey. I think mutations study is

> warrented. See which

> ones you need to fight and which drug does the job.

> Good luck my good

> New Orleans friend!!

>

> Love

>

> Brb

>

>

>

>

> groups.com, " Tracey " <traceyincanada@...> wrote:

> >

> > Hi Lottie,

> >

> > I guess this isn't very surprising as your

> cytogenetics already

> > indicated that you were 100% Ph+.

> >

> > I would suggest though that you get in touch with

> your doctor and

> > insist on a new drug now as SKI obviously isn't

> working for you.

> > There are still several other drugs out there that

> you haven't tried

> > yet and I see no reason to wait until July to do

> so.

> >

> > I would also ask for a mutations test if it's been

> a while since you

> > had one. Different mutations are known to work

> better with different

> > drugs so this would be good information to have.

> >

> > I know it's disappointing to be back to 100% but

> remember that you

> > still have options to try.

> >

> > Take care,

> > Tracey

> >

> >

> >

> > >

> > > This is the result of the complete assay from

> BMA on April 5,

> > 2008. The date 8/2/07 is the date I began the SKI

> trial. They have

> > not decided what the next drug will be, I will

> have to wait until my

> > next appointment in July.

> > > REAL TIME BCR INTERP PB

> > > BCR-ABL qRT-PCR:

> > >

> > > A b2a2 BCR-ABL fusion transcript coding for the

> 210kDa BCR-ABL

> > protein is

> > > detected by real-time PCR.

> > >

> > > The percentage of BCR-ABL to ABL transcripts is

> greater than 100.

> > >

> > > COMMENT: Quantitative real-time PCR analysis

> performed on RNA from

> > this

> > > sample for the BCR-ABL fusion transcript

> resulting from the t(9;22)

> > in

> > > leukemia. BCR-ABL and ABL transcript levels are

> detected

> > simultaneously

> > > and quantitative results expressed as the ratio

> of BCR-ABL to ABL

> > levels.

> > > This ratio may vary up to one-log because of

> methodological

> > reasons. As

> > > of 8/2/07, the assay has shifted to a new

> platform.

> > >

> > > Blessings and peace,

> > > Lottie

> > >

> > >

> > >

> > > [Non-text portions of this message have been

> removed]

> > >

> >

>

>

>

>

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