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Re: harvest and hold

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I have good news!!!! My PCR numbers are down to 0.01

However, as some of you know I knew a friend who had cml and it didnt work out

so well for him. Because of watching his journey i want to have a back up plan.

I dont have a match for transplant so the only back up plan is something called

" harvest and hold " of my own cells when I am PCRU.

On sprycel, I am now at 0.01 and well on my way to PCRU.

The problem is my insurance won't cover the harvest and hold procedure unless

I'm in a clinical trial. Even more problematic is that there are NO clinical

trials for harvest and hold in the US anymore because of the success of the

drugs like gleevec and sprycel.

I am grateful and thankful for the drugs, but i think we should investigate all

options! You see drug development research has money sponsorship because the

drugs are so expensive. Other options have NIH grants but the institutions need

people interested and willing to participate in the research.

Please know that I am very glad we have these drugs but i also know that the

medical research in transplants has changed radically in 10 years. What if in

10 years it's much easier to get a transplant and we could thrive without

medicines? Or maybe we could maintain on a super low dose of the drugs after a

low impact transplant. We just dont know now but without research we wont know.

If you think you may be interested in more info please email me. If we can

compile a group of people interested in such a study, it may be possible to

reopen the study.

Please email me at sionito@... and i can tell you more.

Thanks for 'listening' to my plea.

Rhonda

Sent from my Verizon Wireless BlackBerry

[ ] Chat Reminder - Tuesday June 10, 2008

Chat Reminder - Tuesday June 10, 2008

Photos: Fine dining - Honky Tonk Sat Nite - Sunday Brunch

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My Brother is a perfect match for me. Does anyone know if we could

harvest his bone marrow, he is 62 and if something happened to him I

would be screwed!!!!!

Donna x

>

> Hey.

>

> I just wanted to throw something out. I am not sure if you

already looked

> into this but I got to PCRU on both Gleevec and Spyrcel and I had

the harvest

> in between the two drugs. My insurance wasn't gong to pay for it

either. It

> required my doctor compiling a letter including medical

documentation as

> proof of the needs for this, including the possible benefits

someday if the

> research advanced enough. We had to show that this procedure was

not a clinical

> trial of sorts and that it was medically necessary for a chronic

Leukemic

> patient. Well, whatever he put and sent to them, the insurance

ended up covering

> the whole thing. All my siblings ended up not matching too so I

felt it was

> important for me to have the stem cell harvest (just in case) and

no time

> better then PCRU, so I did it. I would encourage you to look into

that with

> your insurance or doctor if they haven't done so yet. It is

certainly worth

> checking into. You, however, sound like your on top of things so

this has

> probably already been done but if not, best of luck and I will

keep my fingers

> crossed!!! I just wanted to have it in case research came up with

something

> that I could use my own stem cells for. I guess we never know

what is coming

> up next with their discoveries.

>

> Best wishes- you'll be in PCRU in no time!

> Hugs and Hope-

>

> 36

> CML 5/13/05 PCRU

> Gleevec 800mg until 8/07

> Sprycel 100 mg since 9/07

> Wife and mother of 3 (12,9,7)

> # 907 in Zavie's Zero Club

>

>

>

> **************Vote for your city's best dining and nightlife.

City's Best

> 2008. (http://citysbest.aol.com?ncid=aolacg00050000000102)

>

>

>

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Guest guest

wow interesting i mean the harvest hold care to say more about it? new

subject to me.

hi jenifer i was just asking lottie about you yesturday how are you

doing?did'nt you hve surgery a while back? if i'm wrong i apologize if not glad

to

see you post again .

aliza yaffa

**************Vote for your city's best dining and nightlife. City's Best

2008. (http://citysbest.aol.com?ncid=aolacg00050000000102)

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Guest guest

My Brother is a perfect match for me. Does anyone know if we could

harvest his bone marrow, he is 62 and if something happened to him I

would be screwed!!!!!

Donna

_____________

Hi Donna,

I think I have heard of this before in the past....I am not sure that you

would get insurance to pay for it because it is not a present

treatment......or for the cost of storage. I think stored cells can be kept

and used for something like 7 years. You might get an opinion and answer

from a bone marrow transplant center.

C.

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