Guest guest Posted May 16, 2008 Report Share Posted May 16, 2008 Dear Eva, I have never taken Celebrex, but I was on VIOXX and after having already had a stroke, my doctor told me to stop taking it as it caused Strokes and heart attacks,. Well he was too late in telling me, as I had already had the stroke, and I then went on to have the heart attack. Some of us are more vunerable that others, but I would keep tabs on it, like having a test to check for blockages in your heart and your blood pressure. You can buy an inexpensive monitor and keep a log. The 2 drugs are similiar as they were both NSAIDS. Rofecoxib (Vioxx) was withdrawn from the U.S. market in 2004. Rofecoxib is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Rofecoxib works by reducing substances that cause inflammation, pain, and fever in the body. Rofecoxib is used to reduce pain, inflammation. It is important to know that there are risks with all medicines, including the 3 most common prescription NSAIDs: CELEBREX, naproxen, and ibuprofen. In fact, the FDA requires all prescription NSAID pain relievers, including CELEBREX, to have the same cardiovascular warning. Understanding the risks and benefits of different NSAIDs is important. All NSAIDs, including CELEBREX, help relieve arthritis pain, but only you and your doctor can decide which one is right for you. An NSAID like CELEBREX might be an arthritis treatment option. All prescription NSAIDs, including CELEBREX, have the same cardiovascular warning: they may increase the chance of heart attack or stroke, which can lead to death. The right pain relief for you will depend on many factors. These include your history and the severity of your pain. Eva, any drug you want to learn more about can be researched at www.drugstore.com. That is where this information comes from. I also found this about cox inhibitors. The cyclooxygenase (COX) enzyme is actually present in two different forms, COX-1 and COX-2, each with a similar but distinct set of actions. COX-2 is the enzyme responsible for inflammation and fever, whereas COX-1 actually performs other functions such as protecting the gastric mucosa (the lining of the stomach) from the acid that the stomach naturally produces. COX-1 also plays a role in making platelets stick together to form clots. Both reduce blood flow to the kidneys, though. http://www.virtualmedicalcentre.com/treatments.asp?sid=78 After you are done reading all of this, maybe you could explain it to the rest of us. LOL. Blessings, Lottie Quote Link to comment Share on other sites More sharing options...
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