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WBC at diagnosis

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I was just curious about white blood counts at diagnosis time. And I think that

one of you may have asked me what mine was.

I had one complete blood count done on the recommendation of a pathologist who

thought he saw something unusual in a fine needle aspiration sample. That was

done but sat unnoticed on a vacationing doctor's desk for about 10 days. When

the report was finally unearthed, there was panic...enough to get me admitted

into the Penn State Cancer Institute at Hershey Medical Center within 24 hours.

I was just stunned (especially when they started talking about blast crisis). My

WBC peaked at about 190. But the good folks at Hershey had the diagnosis nailed

(pending the BMB) within a couple of hours. No blast crisis...just the chronic

stage.

Took a few weeks of hydrea and allopurinol to bring the counts down to the 10-12

range before starting the Gleevec. Happy to report that even after just a month

on the Gleevec, the doctors say my blood counts are just about normal now. Won't

know about the rest until the next BMB in the fall. That'll be interesting!

Is my experience usual, or am I just lucky?

Martha B

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Hi Martha,

Your diagnosis is pretty usual. My WBC was 150 at diagnosis time. The CML

was found because of a regular blood test.

If they didn't do a PCR test at diagnosis time, ask them to do one at your

next appointment. It is important to have one early so that you will have

something to compare to later on.

Looking forward to enrolling you in the Zero Club real soon,

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Martha

Sent: June 15, 2008 9:38 PM

Subject: [ ] WBC at diagnosis

I was just curious about white blood counts at diagnosis time. And I think

that one of you may have asked me what mine was.

I had one complete blood count done on the recommendation of a pathologist

who thought he saw something unusual in a fine needle aspiration sample.

That was done but sat unnoticed on a vacationing doctor's desk for about 10

days. When the report was finally unearthed, there was panic...enough to get

me admitted into the Penn State Cancer Institute at Hershey Medical Center

within 24 hours. I was just stunned (especially when they started talking

about blast crisis). My WBC peaked at about 190. But the good folks at

Hershey had the diagnosis nailed (pending the BMB) within a couple of hours.

No blast crisis...just the chronic stage.

Took a few weeks of hydrea and allopurinol to bring the counts down to the

10-12 range before starting the Gleevec. Happy to report that even after

just a month on the Gleevec, the doctors say my blood counts are just about

normal now. Won't know about the rest until the next BMB in the fall.

That'll be interesting!

Is my experience usual, or am I just lucky?

Martha B

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252. I wasn't feeling so good at that point, big side pain, weight loss,

delayed a month but had a deep dive scheduled so I eventually called Kaiser

who gave me an appointment same afternoon (I wasn't hot about going to the

emergency room to wait hours). I remember the nurse passed me to a md who

told me : you are not doing well at all sir, you need to see a dr right now,

and no you can't dive. The dr ausculted me, found my spleen close to

bursting, and ordered chest xray and blood tests, then I got back to the

office. In the evening I got a call from a nurse telling me to get to the

hospital asap, what I negotiated into an appointment in the morning, where

the dr gave me the dx. About two months later I was back diving :)

Marcos.

On Sun, Jun 15, 2008 at 6:55 PM, Zavie miller <zmiller@...> wrote:

> Hi Martha,

>

> Your diagnosis is pretty usual. My WBC was 150 at diagnosis time. The CML

> was found because of a regular blood test.

>

> If they didn't do a PCR test at diagnosis time, ask them to do one at your

> next appointment. It is important to have one early so that you will have

> something to compare to later on.

>

> Looking forward to enrolling you in the Zero Club real soon,

>

> Zavie

>

> Zavie (age 70)

> 67 Shoreham Avenue

> Ottawa, Canada, K2G 3X3

> dxd AUG/99

> INF OCT/99 to FEB/00, CHF

> No meds FEB/00 to JAN/01

> Gleevec since MAR/27/01 (400 mg)

> CCR SEP/01. #102 in Zero Club

> 2.8 log reduction Sep/05

> 3.0 log reduction Jan/06

> 2.9 log reduction Feb/07

> 3.5 log reduction Jan/08

> 3.6 log reduction Apr/08

> e-mail: zmiller@... <zmiller%40sympatico.ca>

> Tel: 613-726-1117

> Fax: 309-296-0807

> Cell: 613-202-0204

> ID: zaviem

> YM: zaviemiller

> Skype: Zavie

>

> _____

>

> From: <%40> [mailto:

> <%40>] On Behalf Of Martha

>

> Sent: June 15, 2008 9:38 PM

> <%40>

> Subject: [ ] WBC at diagnosis

>

> I was just curious about white blood counts at diagnosis time. And I think

> that one of you may have asked me what mine was.

>

> I had one complete blood count done on the recommendation of a pathologist

> who thought he saw something unusual in a fine needle aspiration sample.

> That was done but sat unnoticed on a vacationing doctor's desk for about 10

> days. When the report was finally unearthed, there was panic...enough to

> get

> me admitted into the Penn State Cancer Institute at Hershey Medical Center

> within 24 hours. I was just stunned (especially when they started talking

> about blast crisis). My WBC peaked at about 190. But the good folks at

> Hershey had the diagnosis nailed (pending the BMB) within a couple of

> hours.

> No blast crisis...just the chronic stage.

>

> Took a few weeks of hydrea and allopurinol to bring the counts down to the

> 10-12 range before starting the Gleevec. Happy to report that even after

> just a month on the Gleevec, the doctors say my blood counts are just about

> normal now. Won't know about the rest until the next BMB in the fall.

> That'll be interesting!

>

> Is my experience usual, or am I just lucky?

>

> Martha B

>

>

>

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Hi Martha,

My white count was 86 when I was diagnosed but the white count itself

isn't really the decisive factor when determining the phase of CML.

I've seen patients with a WBC of 500 who were in early chronic phase

and others with a WBC of less than 20 who were in blast phase. This

is why we can't rely on just a CBC to monitor our disease.

The other contributing factors that help determine which phase you

are in at diagnosis are blast count, basophil count, spleen size,

platelet count and whether or not there were other clonal evolutions

on the BMB.

The majority of patients do well with Gleevec and it sounds like you

fit into that category.

Take care,

Tracey

>

> I was just curious about white blood counts at diagnosis time. And

I think that one of you may have asked me what mine was.

>

> I had one complete blood count done on the recommendation of a

pathologist who thought he saw something unusual in a fine needle

aspiration sample. That was done but sat unnoticed on a vacationing

doctor's desk for about 10 days. When the report was finally

unearthed, there was panic...enough to get me admitted into the Penn

State Cancer Institute at Hershey Medical Center within 24 hours. I

was just stunned (especially when they started talking about blast

crisis). My WBC peaked at about 190. But the good folks at Hershey

had the diagnosis nailed (pending the BMB) within a couple of hours.

No blast crisis...just the chronic stage.

>

> Took a few weeks of hydrea and allopurinol to bring the counts down

to the 10-12 range before starting the Gleevec. Happy to report that

even after just a month on the Gleevec, the doctors say my blood

counts are just about normal now. Won't know about the rest until the

next BMB in the fall. That'll be interesting!

>

> Is my experience usual, or am I just lucky?

>

> Martha B

>

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Hi Martha, My WBC was one of those over 500, and I was getting along just

fine, normal CML markers screaming I had it, but was working hard and getting

along fine. I ended up in the ER in A-Fib, due to my blood being so out of

whack, you just never know. I went in thinking heart attack, come out a CML

patient.

Chris

**************Vote for your city's best dining and nightlife. City's Best

2008. (http://citysbest.aol.com?ncid=aolacg00050000000102)

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539,000!!!! and only the chronic phase too!!!

Donna x

>

> > Hi Martha,

> >

> > Your diagnosis is pretty usual. My WBC was 150 at diagnosis time.

The CML

> > was found because of a regular blood test.

> >

> > If they didn't do a PCR test at diagnosis time, ask them to do

one at your

> > next appointment. It is important to have one early so that you

will have

> > something to compare to later on.

> >

> > Looking forward to enrolling you in the Zero Club real soon,

> >

> > Zavie

> >

> > Zavie (age 70)

> > 67 Shoreham Avenue

> > Ottawa, Canada, K2G 3X3

> > dxd AUG/99

> > INF OCT/99 to FEB/00, CHF

> > No meds FEB/00 to JAN/01

> > Gleevec since MAR/27/01 (400 mg)

> > CCR SEP/01. #102 in Zero Club

> > 2.8 log reduction Sep/05

> > 3.0 log reduction Jan/06

> > 2.9 log reduction Feb/07

> > 3.5 log reduction Jan/08

> > 3.6 log reduction Apr/08

> > e-mail: zmiller@... <zmiller%40sympatico.ca>

> > Tel: 613-726-1117

> > Fax: 309-296-0807

> > Cell: 613-202-0204

> > ID: zaviem

> > YM: zaviemiller

> > Skype: Zavie

> >

> > _____

> >

> > From: <%40> [mailto:

> > <%40>] On Behalf Of Martha

> >

> > Sent: June 15, 2008 9:38 PM

> > <%40>

> > Subject: [ ] WBC at diagnosis

> >

> > I was just curious about white blood counts at diagnosis time.

And I think

> > that one of you may have asked me what mine was.

> >

> > I had one complete blood count done on the recommendation of a

pathologist

> > who thought he saw something unusual in a fine needle aspiration

sample.

> > That was done but sat unnoticed on a vacationing doctor's desk

for about 10

> > days. When the report was finally unearthed, there was

panic...enough to

> > get

> > me admitted into the Penn State Cancer Institute at Hershey

Medical Center

> > within 24 hours. I was just stunned (especially when they started

talking

> > about blast crisis). My WBC peaked at about 190. But the good

folks at

> > Hershey had the diagnosis nailed (pending the BMB) within a

couple of

> > hours.

> > No blast crisis...just the chronic stage.

> >

> > Took a few weeks of hydrea and allopurinol to bring the counts

down to the

> > 10-12 range before starting the Gleevec. Happy to report that

even after

> > just a month on the Gleevec, the doctors say my blood counts are

just about

> > normal now. Won't know about the rest until the next BMB in the

fall.

> > That'll be interesting!

> >

> > Is my experience usual, or am I just lucky?

> >

> > Martha B

> >

> >

> >

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