Vaccine for CML in research stage.

July 20, 2008

Good news on the leukemia front.

June 20, 2008. Progress in the development of a leukemia vaccine has been

enough to win a five-year grant from the National Cancer Institute to continue

studying the approach. " The hope really is to get patients off Gleevec

ultimately, " said Dr. Lee of Stanford University School of Medicine, a

leukemia specialist who worked on the study. " It's very very early days, but

that is the hope. " This approach enlists the immune system.

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March 7, 2008. The majority of women who become pregnant while taking the

cancer drug Gleevec will probably have a successful outcome. However, there is a

substantial risk of serious fetal malformations, according to a study reported

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December 11, 2007 . A new leukemia vaccine under investigation extends

patients' event-free survival by more than three-fold, from 2.4 month with

conventional treatment to 8.7 months, investigators at the University of Texas

M. D. Cancer Center in Houston reported at the 49th annual meeting of

the American Society of Hematology held in Atlanta. " The residual leukemia

cells disappear over time in the responders and we cannot detect them after a

time, " Qazilbash said. " The molecular markers of leukemia disappear. " The best

time to use the vaccine is after first-line treatment fails, he suggests. " We

don't see this used as first-line treatment. "

Blessings,

Lottie

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