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Dear Group,

I read every letter and I think everyone is right. Each has a different

opinion, a different experience and emotions, so all thoughts and questions are

valid and true to them singly. Some experience the same side effects, so they

can relate to that person. I relate to everyone who has been in numerous

trials, because we share that same experience. Almost all of my trials have

been at MDACC, but Bobby is the Travel Queen, she really gets around. I think

Len would be next. She certainly has the record for staying away from home the

longest. When they were passing out genes, we not only got the one with CML, we

got the one for perseverance. Warriors all are we, and since we have the same

enemy, we stick together and plan our stratergies together. We share our pain

with each other, and our victories with Zavie's s and Yipees.

Will get back to you as soon as I can,

Blessings from me to you,

Lottie

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Hi Lottie,

One thing we must never forget. The majority of patients have not been in

trials and it is because of those who participated in trials who made iit

safe for us who came afterwards. Many of us are doing well on the current

approved meds because of the brave warriors who tested the drugs. If down

the road one of us will need a drug like XL228, it will be because of

patients like our own Bobby that participated in a trial to help figure out

the correct dosage and to be the guinea pig to learn what the side affects

are.

I can claim to be part of a clinical trial for Gleevec, but that would be a

sham. The trial that I was in was called the expanded access trial (#113).

This was a trial cooked up by Novartis to make Gleevec available to those

patients who needed the drug and couldn't get it.. All the clinical were

closed and Novartis was waiting for FDA approval before it could be released

to the public. I am ever in debt to Novartis and all the trial warriors for

saving my life.

Thank you all,

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-282-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Lottie

Duthu

Sent: September 29, 2008 6:29 PM

CML

Subject: [ ] Everyone is right

Dear Group,

I read every letter and I think everyone is right. Each has a different

opinion, a different experience and emotions, so all thoughts and questions

are valid and true to them singly. Some experience the same side effects, so

they can relate to that person. I relate to everyone who has been in

numerous trials, because we share that same experience. Almost all of my

trials have been at MDACC, but Bobby is the Travel Queen, she really gets

around. I think Len would be next. She certainly has the record for staying

away from home the longest. When they were passing out genes, we not only

got the one with CML, we got the one for perseverance. Warriors all are we,

and since we have the same enemy, we stick together and plan our stratergies

together. We share our pain with each other, and our victories with Zavie's

s and Yipees.

Will get back to you as soon as I can,

Blessings from me to you,

Lottie

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