RE: BMT survival rates compared to Gleevec survival rates

[Guest guest]

Hi! I am one of the BMT patients.  15months post bone marrow transplant my last

pcr was in the negative range while the other two had 1 cell in 100,000 this

year.  My biopsy done in Aug showed 100% donor my oldest sister.  I found out in

Aug 2005 wbc 220,000.  I have hashimoto thyroiditis auto immune and taking

synthroid to bring the tsh levels down.  I have a small nodule on the old

thryoid and if it gets bigger they can biopsy.  The only thing still out of

whack is the liver enzymes they are elevated but not too bad.  I have learned

alot and hope I remain in the neg because gleevec and sprycel did not work thus

bmt.  Just wanted to share.  I read alot you guys are great!     

A

________________________________

From: Tracey <traceyincanada@...>

Sent: Wednesday, November 19, 2008 11:42:09 AM

Subject: [ ] BMT survival rates bcompared to Gleevec survival rates

Hi Everyone,

It's not so much an issue these days as most doctors now realize that

the risks involved with transplants often outweigh their perceived

benefits therefore most doctors today will recommend Gleevec over a BMT

unless there's a clinical reason to pursue transplant (failure of

Gleevec and the newer drugs).

Here's an abstract that deals with the issue:

http://ash.confex. com/ash/2008/ webprogram/ Paper9503. html

The bottom line is that after 5 years, the survival rate for Gleevec

patients was almost 95% while the survival rate for transplant patients

was 71%.

Tracey

[Guest guest]

Congratulations Christa on a great result from your transplant!

There will always be some patients who will have to go down the BMT

route when they find themselves in your boat, having not responded to

the available drugs so it's really great to hear your success story

which will no doubt give comfort to those in that situation.

The liver is a very resilient organ and can withstand much

punishment. Hopefully yours will settle down soon.

Take care,

Tracey

>

> Hi! I am one of the BMT patients.  15months post bone marrow

transplant my last pcr was in the negative range while the other two

had 1 cell in 100,000 this year.  My biopsy done in Aug showed 100%

donor my oldest sister.  I found out in Aug 2005 wbc 220,000.  I have

hashimoto thyroiditis auto immune and taking synthroid to bring the

tsh levels down.  I have a small nodule on the old thryoid and if it

gets bigger they can biopsy.  The only thing still out of whack is

the liver enzymes they are elevated but not too bad.  I have learned

alot and hope I remain in the neg because gleevec and sprycel did not

work thus bmt.  Just wanted to share.  I read alot you guys are

great!     

>

> A

>

>

> ________________________________

> From: Tracey <traceyincanada@...>

>

> Sent: Wednesday, November 19, 2008 11:42:09 AM

> Subject: [ ] BMT survival rates bcompared to Gleevec survival

rates

>

>

> Hi Everyone,

>

> It's not so much an issue these days as most doctors now realize

that

> the risks involved with transplants often outweigh their perceived

> benefits therefore most doctors today will recommend Gleevec over a

BMT

> unless there's a clinical reason to pursue transplant (failure of

> Gleevec and the newer drugs).

>

> Here's an abstract that deals with the issue:

>

> http://ash.confex. com/ash/2008/ webprogram/ Paper9503. html

>

> The bottom line is that after 5 years, the survival rate for

Gleevec

> patients was almost 95% while the survival rate for transplant

patients

> was 71%.

>

> Tracey

>

>

>

>

>

>

>

[Guest guest]

O!!! YIPPEEE!!!

Number 1229 in the Zero Club

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-282-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of

Christa Boyd

Sent: November 19, 2008 12:05 PM

Subject: Re: [ ] BMT survival rates compared to Gleevec survival rates

Hi! I am one of the BMT patients. 15months post bone marrow transplant my

last pcr was in the negative range while the other two had 1 cell in 100,000

this year. My biopsy done in Aug showed 100% donor my oldest sister. I

found out in Aug 2005 wbc 220,000. I have hashimoto thyroiditis auto immune

and taking synthroid to bring the tsh levels down. I have a small nodule on

the old thryoid and if it gets bigger they can biopsy. The only thing still

out of whack is the liver enzymes they are elevated but not too bad. I have

learned alot and hope I remain in the neg because gleevec and sprycel did

not work thus bmt. Just wanted to share. I read alot you guys are great!

A

________________________________

From: Tracey <traceyincanada@ <mailto:traceyincanada%40> >

groups (DOT) <mailto:%40> com

Sent: Wednesday, November 19, 2008 11:42:09 AM

Subject: [ ] BMT survival rates bcompared to Gleevec survival rates

Hi Everyone,

It's not so much an issue these days as most doctors now realize that

the risks involved with transplants often outweigh their perceived

benefits therefore most doctors today will recommend Gleevec over a BMT

unless there's a clinical reason to pursue transplant (failure of

Gleevec and the newer drugs).

Here's an abstract that deals with the issue:

http://ash.confex. com/ash/2008/ webprogram/ Paper9503. html

The bottom line is that after 5 years, the survival rate for Gleevec

patients was almost 95% while the survival rate for transplant patients

was 71%.

Tracey