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Re: Glivec 800mg

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Hi all

Without whinging and going into details of what is happening to/with me, how

many men and women out there are on the full dose of Glivec 800mg? How are

you coping with it? And most importantly what results are you getting?

I would appreciate all comments regarding side effects.

Thanks so much,

Jackie

On 800mg since first diagnosis in Nov '04.

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>Hi Jackie,

I've been on 800 for 6 years. My results have been

excellent. Very low PCR. At the time I bumped up the hope was the

higher dose would hold me for 6 months so it has been very

successful for me.

I have a difficult time with side effects but I'm not

typical as I have a history of intolerance to drugs and my responses

can be extreme. I would say fatigue with a capital F is the worst.

That said, lots of people do very well.

I've heard some through the years say they barely noticed the

difference when they went to 800. I hope you hear from some of them.

Good luck Ellen

> Hi all

>

>

>

> Without whinging and going into details of what is happening

to/with me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you

getting?

>

>

>

> I would appreciate all comments regarding side effec

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

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I'm on 400 mg., and I feel like I'm sleeping my life away. I can't even imagine

what 800 mg. would be like.

From: jackie@...

Date: Fri, 9 Jan 2009 22:47:49 +1100

Subject: RE: [ ] Glivec 800mg

Hi all

Without whinging and going into details of what is happening to/with me, how

many men and women out there are on the full dose of Glivec 800mg? How are

you coping with it? And most importantly what results are you getting?

I would appreciate all comments regarding side effects.

Thanks so much,

Jackie

On 800mg since first diagnosis in Nov '04.

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Granny is on 400 mg. and she pukes hers up about 3 times a week. And she has to

take a nap everyday. Of course she is 81 yrs. old. I can't imagine what any

higher dose would do.

--

Kristie Skipper

skipper3@...

--------- RE: [ ] Glivec 800mg

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

>

> Hi all

>

>

>

> Without whinging and going into details of what is happening to/with me, how

>

> many men and women out there are on the full dose of Glivec 800mg? How are

>

> you coping with it? And most importantly what results are you getting?

>

>

>

> I would appreciate all comments regarding side effects.

>

>

>

> Thanks so much,

>

>

>

> Jackie

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

Link to comment
Share on other sites

wow it really is very different for everyone. I'm on 400 and I had all the

cosmetic stuff ,puffy eyes skin rashes etc and the bone pain, muscle cramps but

although I was queasy I never threw up and although a bit tired I still work

full time and I'm in training for my third 1/2 marathon. I really should count

my blessings. My brain is slower and scrambled. I didn't get laid off in the

first round but it sounds like there is another one coming. Oh well- I'll have

time to write my book. I told my friends I will be on the corner with a sign-

Will work for Chemo.

> From: skipper3@... <skipper3@...>

> Subject: RE: [ ] Glivec 800mg

>

> Date: Friday, January 9, 2009, 11:49 AM

> Granny is on 400 mg. and she pukes hers up about 3 times a

> week. And she has to take a nap everyday. Of course she is

> 81 yrs. old. I can't imagine what any higher dose would

> do.

>

> --

> Kristie Skipper

> skipper3@...

>

> --------- RE: [ ] Glivec 800mg

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > Hi all

> >

> >

> >

> > Without whinging and going into details of what is

> happening to/with me, how

> >

> > many men and women out there are on the full dose of

> Glivec 800mg? How are

> >

> > you coping with it? And most importantly what results

> are you getting?

> >

> >

> >

> > I would appreciate all comments regarding side

> effects.

> >

> >

> >

> > Thanks so much,

> >

> >

> >

> > Jackie

> >

> >

> >

> > On 800mg since first diagnosis in Nov '04.

> >

> >

> >

> >

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I *love* that idea! Boy, that's us all over.

From: Sionito@...

Date: Fri, 9 Jan 2009 21:40:09 +0000

Subject: Re: [ ] Glivec 800mg

Wow a marathon!!! Congrats!

I work full time, my brain is mushy too at times. My job is touchy at the

moment and i love your sign idea... Maybe i will make a t-shirt for us???

Will work for chemo!

A cancer patient's nightmare is not death, it's losing our insurance!

Sent from my Verizon Wireless BlackBerry

RE: [ ] Glivec 800mg

>

> Date: Friday, January 9, 2009, 11:49 AM

> Granny is on 400 mg. and she pukes hers up about 3 times a

> week. And she has to take a nap everyday. Of course she is

> 81 yrs. old. I can't imagine what any higher dose would

> do.

>

> --

> Kristie Skipper

> skipper3@...

>

> --------- RE: [ ] Glivec 800mg

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > Hi all

> >

> >

> >

> > Without whinging and going into details of what is

> happening to/with me, how

> >

> > many men and women out there are on the full dose of

> Glivec 800mg? How are

> >

> > you coping with it? And most importantly what results

> are you getting?

> >

> >

> >

> > I would appreciate all comments regarding side

> effects.

> >

> >

> >

> > Thanks so much,

> >

> >

> >

> > Jackie

> >

> >

> >

> > On 800mg since first diagnosis in Nov '04.

> >

> >

> >

> >

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Share on other sites

Wow a marathon!!! Congrats!

I work full time, my brain is mushy too at times. My job is touchy at the

moment and i love your sign idea... Maybe i will make a t-shirt for us???

Will work for chemo!

A cancer patient's nightmare is not death, it's losing our insurance!

Sent from my Verizon Wireless BlackBerry

RE: [ ] Glivec 800mg

>

> Date: Friday, January 9, 2009, 11:49 AM

> Granny is on 400 mg. and she pukes hers up about 3 times a

> week. And she has to take a nap everyday. Of course she is

> 81 yrs. old. I can't imagine what any higher dose would

> do.

>

> --

> Kristie Skipper

> skipper3@...

>

> --------- RE: [ ] Glivec 800mg

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > Hi all

> >

> >

> >

> > Without whinging and going into details of what is

> happening to/with me, how

> >

> > many men and women out there are on the full dose of

> Glivec 800mg? How are

> >

> > you coping with it? And most importantly what results

> are you getting?

> >

> >

> >

> > I would appreciate all comments regarding side

> effects.

> >

> >

> >

> > Thanks so much,

> >

> >

> >

> > Jackie

> >

> >

> >

> > On 800mg since first diagnosis in Nov '04.

> >

> >

> >

> >

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Share on other sites

I also cannot comment on 800mg. of Gleevec, but if it wipes you out its

certainly natural.  I have been on 400mg. since 2000, and I also feel like I

could just sleep my life away.  The fatigue is the worst, then throw in the

periodic nausea ( only if I do not eat a substantial meal before taking my med)

..  The puffy eyes are still bad.  They take on a different shape every morning. 

My husband will say, lets see what your eyes look like today. He is amazed at

how they swell, and then I apply ice pack.  Within 10 minutes I look normal.  I

could go on and on with all the experiences with 400mg.  If your on 800mg. and

its doing its thing, concentrate on the results your getting with your CML.

> From: skipper3@... <skipper3@...>

> Subject: RE: [ ] Glivec 800mg

>

> Date: Friday, January 9, 2009, 11:49 AM

> Granny is on 400 mg. and she pukes hers up about 3 times a

> week. And she has to take a nap everyday. Of course she is

> 81 yrs. old. I can't imagine what any higher dose would

> do.

>

> --

> Kristie Skipper

> skipper3@...

>

> --------- RE: [ ] Glivec 800mg

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > Hi all

> >

> >

> >

> > Without whinging and going into details of what is

> happening to/with me, how

> >

> > many men and women out there are on the full dose of

> Glivec 800mg? How are

> >

> > you coping with it? And most importantly what results

> are you getting?

> >

> >

> >

> > I would appreciate all comments regarding side

> effects.

> >

> >

> >

> > Thanks so much,

> >

> >

> >

> > Jackie

> >

> >

> >

> > On 800mg since first diagnosis in Nov '04.

> >

> >

> >

> >

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Share on other sites

Hi Jackie How did you get on 800! My onc wanted me to go to 800 off 400 because

my bcr/able went up a few points.Ofter getting feedback from those that know I

settled on 600 My onc was not to happy.Since firring him my 2 onc said I would

have been fine on 400 .It took 2years 8 months to get pcru.He also said now I

have to stay on 600 I get by pretty good.Switching to 6 pills from 3 400 and 2

100 which is 2 prescriptions 

________________________________

From: ets618 <ets618@...>

Sent: Friday, January 9, 2009 9:03:52 AM

Subject: Re: [ ] Glivec 800mg

>Hi Jackie,

I've been on 800 for 6 years. My results have been

excellent. Very low PCR. At the time I bumped up the hope was the

higher dose would hold me for 6 months so it has been very

successful for me.

I have a difficult time with side effects but I'm not

typical as I have a history of intolerance to drugs and my responses

can be extreme. I would say fatigue with a capital F is the worst.

That said, lots of people do very well.

I've heard some through the years say they barely noticed the

difference when they went to 800. I hope you hear from some of them.

Good luck Ellen

> Hi all

>

>

>

> Without whinging and going into details of what is happening

to/with me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you

getting?

>

>

>

> I would appreciate all comments regarding side effec

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

Link to comment
Share on other sites

Hi :-)

When I was originally diagnosed by white cells were high, going from 200 to

375 in a week. My spleen was massive. I was very much in chronic stage, but

now wonder if things, even then, were starting to rev up. The doctor wanted

to fight it in the guts from the start and he did the right thing, giving me

800mg.

I have gone from 375% to 0.02.

The side effects are pretty bad though. I had extremely heavy menstrual

bleeding from the start (now on the pill permanently due to large fibroid,

glivec induced), fragile skin, no colour in hair or skin, diarrhea most

days, swelling around the eye (but not badly), my bones feel cold all the

time (always wearing full clothes, even in summer), flushing skin of the

face, depression, tiredness, Fatigue (capital F). The list goes on .

I am 47 and have I have two beautiful daughters who I live for.

I am still working full time, from home. I run a transcription company with

a partner in Perth and we're doing A-OK.

I am considering to ask my onc to reduce me to 600, but a little scared as

my results are still bouncing around a little.

Jackie

_____

From: [mailto: ] On Behalf Of

Shipley

Sent: Saturday, 10 January 2009 12:45 PM

Subject: Re: [ ] Glivec 800mg

Hi Jackie How did you get on 800! My onc wanted me to go to 800 off 400

because my bcr/able went up a few points.Ofter getting feedback from those

that know I settled on 600 My onc was not to happy.Since firring him my 2

onc said I would have been fine on 400 .It took 2years 8 months to get

pcru.He also said now I have to stay on 600 I get by pretty good.Switching

to 6 pills from 3 400 and 2 100 which is 2 prescriptions

________________________________

From: ets618 <ets618 (DOT) <mailto:ets618%40> com>

groups (DOT) <mailto:%40> com

Sent: Friday, January 9, 2009 9:03:52 AM

Subject: Re: [ ] Glivec 800mg

>Hi Jackie,

I've been on 800 for 6 years. My results have been

excellent. Very low PCR. At the time I bumped up the hope was the

higher dose would hold me for 6 months so it has been very

successful for me.

I have a difficult time with side effects but I'm not

typical as I have a history of intolerance to drugs and my responses

can be extreme. I would say fatigue with a capital F is the worst.

That said, lots of people do very well.

I've heard some through the years say they barely noticed the

difference when they went to 800. I hope you hear from some of them.

Good luck Ellen

> Hi all

>

>

>

> Without whinging and going into details of what is happening

to/with me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you

getting?

>

>

>

> I would appreciate all comments regarding side effec

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

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Share on other sites

I tried 800, but really struggled with the

side effects and quite honestly I don't

think there is a benefit to 800 over more

tolerable lower doses of 600 or 400 that

are very effective at reaching PCRU.

Sent from my iPhone

On Jan 10, 2009, at 7:35 AM, " Jackie Petropoulos "

<jackie@...> wrote:

> Hi :-)

>

> When I was originally diagnosed by white cells were high, going from

> 200 to

> 375 in a week. My spleen was massive. I was very much in chronic

> stage, but

> now wonder if things, even then, were starting to rev up. The doctor

> wanted

> to fight it in the guts from the start and he did the right thing,

> giving me

> 800mg.

>

> I have gone from 375% to 0.02.

>

> The side effects are pretty bad though. I had extremely heavy

> menstrual

> bleeding from the start (now on the pill permanently due to large

> fibroid,

> glivec induced), fragile skin, no colour in hair or skin, diarrhea

> most

> days, swelling around the eye (but not badly), my bones feel cold

> all the

> time (always wearing full clothes, even in summer), flushing skin of

> the

> face, depression, tiredness, Fatigue (capital F). The list goes on .

>

> I am 47 and have I have two beautiful daughters who I live for.

>

> I am still working full time, from home. I run a transcription

> company with

> a partner in Perth and we're doing A-OK.

>

> I am considering to ask my onc to reduce me to 600, but a little

> scared as

> my results are still bouncing around a little.

>

> Jackie

>

> _____

>

> From: [mailto: ] On Behalf

> Of

> Shipley

> Sent: Saturday, 10 January 2009 12:45 PM

>

> Subject: Re: [ ] Glivec 800mg

>

> Hi Jackie How did you get on 800! My onc wanted me to go to 800 off

> 400

> because my bcr/able went up a few points.Ofter getting feedback from

> those

> that know I settled on 600 My onc was not to happy.Since firring him

> my 2

> onc said I would have been fine on 400 .It took 2years 8 months to get

> pcru.He also said now I have to stay on 600 I get by pretty

> good.Switching

> to 6 pills from 3 400 and 2 100 which is 2 prescriptions

>

> ________________________________

> From: ets618 <ets618 (DOT) <mailto:ets618%40> com>

> groups (DOT) <mailto:%40> com

> Sent: Friday, January 9, 2009 9:03:52 AM

> Subject: Re: [ ] Glivec 800mg

>

>

> >Hi Jackie,

>

> I've been on 800 for 6 years. My results have been

> excellent. Very low PCR. At the time I bumped up the hope was the

> higher dose would hold me for 6 months so it has been very

> successful for me.

>

> I have a difficult time with side effects but I'm not

> typical as I have a history of intolerance to drugs and my responses

> can be extreme. I would say fatigue with a capital F is the worst.

> That said, lots of people do very well.

> I've heard some through the years say they barely noticed the

> difference when they went to 800. I hope you hear from some of them.

> Good luck Ellen

> > Hi all

> >

> >

> >

> > Without whinging and going into details of what is happening

> to/with me, how

> > many men and women out there are on the full dose of Glivec 800mg?

> How are

> > you coping with it? And most importantly what results are you

> getting?

> >

> >

> >

> > I would appreciate all comments regarding side effec

> >

> > Thanks so much,

> >

> > Jackie

> >

> >

> >

> >

> >

> >

> >

> > On 800mg since first diagnosis in Nov '04.

> >

> >

> >

> >

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Share on other sites

Hi Jackie,

When I was first diagnosed in 2001, Gleevec (Imatinib) was so new that it took a

fellow CML patient who was also an MD to suggest that when 400 mg didn't work

for me that I try 800 mg instead. My doc agreed to it since there was nothing

in the Imatinib protocol to prevent it.

The side effects were enormous -- bone pain, stomach bleeds and fatigue.

However, since there was no other viable option at the time I have to say that

it was worth it to finally reach CCR (never PCRU) for a relatively short period

of time. And this is the important part: it held me until dasatinib became

available in trial. It was a rough way to go, I have to say. BUT, it was the

ONLY way to go at the time. Now I'm on dasatinib (Sprycel) and am PCRU and have

been for 3 years.

L

Re: [ ] Glivec 800mg

>Hi Jackie,

I've been on 800 for 6 years. My results have been

excellent. Very low PCR. At the time I bumped up the hope was the

higher dose would hold me for 6 months so it has been very

successful for me.

I have a difficult time with side effects but I'm not

typical as I have a history of intolerance to drugs and my responses

can be extreme. I would say fatigue with a capital F is the worst.

That said, lots of people do very well.

I've heard some through the years say they barely noticed the

difference when they went to 800. I hope you hear from some of them.

Good luck Ellen

> Hi all

>

>

>

> Without whinging and going into details of what is happening

to/with me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you

getting?

>

>

>

> I would appreciate all comments regarding side effec

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

Link to comment
Share on other sites

> The side effects are pretty bad though. I had extremely heavy

menstrual bleeding from the start (now on the pill permanently due to

large fibroid, glivec induced),

*******************************************

Hi Jackie,

Sorry to hear about all the side effects you're having. I was

wondering if you could tell me how they determined that your fibroids

were caused by the Gleevec. I've searched a number of medical sites

and wasn't able to find a connection.

I also have fibroids but was told that most women over 35 have them

and the older a woman gets, the more problems the fibroids cause due

to the higher estrogen levels. After menopause when estrogen finally

drops, the fibroids are supposed to cause less problems. Something

to look forward to I guess.

I'd be curious to see any information you have regarding this.

Tracey

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My hat is off to you for maintaining a business and raising two daughters. My

god! How do you do it! You are made of strong stuff, Jackie.

From: jackie@...

Date: Sat, 10 Jan 2009 23:35:02 +1100

Subject: RE: [ ] Glivec 800mg

Hi :-)

When I was originally diagnosed by white cells were high, going from 200 to

375 in a week. My spleen was massive. I was very much in chronic stage, but

now wonder if things, even then, were starting to rev up. The doctor wanted

to fight it in the guts from the start and he did the right thing, giving me

800mg.

I have gone from 375% to 0.02.

The side effects are pretty bad though. I had extremely heavy menstrual

bleeding from the start (now on the pill permanently due to large fibroid,

glivec induced), fragile skin, no colour in hair or skin, diarrhea most

days, swelling around the eye (but not badly), my bones feel cold all the

time (always wearing full clothes, even in summer), flushing skin of the

face, depression, tiredness, Fatigue (capital F). The list goes on .

I am 47 and have I have two beautiful daughters who I live for.

I am still working full time, from home. I run a transcription company with

a partner in Perth and we're doing A-OK.

I am considering to ask my onc to reduce me to 600, but a little scared as

my results are still bouncing around a little.

Jackie

_____

From: [mailto: ] On Behalf Of

Shipley

Sent: Saturday, 10 January 2009 12:45 PM

Subject: Re: [ ] Glivec 800mg

Hi Jackie How did you get on 800! My onc wanted me to go to 800 off 400

because my bcr/able went up a few points.Ofter getting feedback from those

that know I settled on 600 My onc was not to happy.Since firring him my 2

onc said I would have been fine on 400 .It took 2years 8 months to get

pcru.He also said now I have to stay on 600 I get by pretty good.Switching

to 6 pills from 3 400 and 2 100 which is 2 prescriptions

________________________________

From: ets618 <ets618 (DOT) <mailto:ets618%40> com>

groups (DOT) <mailto:%40> com

Sent: Friday, January 9, 2009 9:03:52 AM

Subject: Re: [ ] Glivec 800mg

>Hi Jackie,

I've been on 800 for 6 years. My results have been

excellent. Very low PCR. At the time I bumped up the hope was the

higher dose would hold me for 6 months so it has been very

successful for me.

I have a difficult time with side effects but I'm not

typical as I have a history of intolerance to drugs and my responses

can be extreme. I would say fatigue with a capital F is the worst.

That said, lots of people do very well.

I've heard some through the years say they barely noticed the

difference when they went to 800. I hope you hear from some of them.

Good luck Ellen

> Hi all

>

>

>

> Without whinging and going into details of what is happening

to/with me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you

getting?

>

>

>

> I would appreciate all comments regarding side effec

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

Link to comment
Share on other sites

Hi Tracey,

The reason I came to that conclusion (along with the gynecologist), is

because I had regular periods until the very month I started Glivec in the

December. From that very first month my period was so heavy, I thought I

would have to be hospitalized. Two months later I saw the gynecologist who

saw the (then) small fibroid and said that this was so small it shouldn't

affect my cycle at all. We then put the heavy bleeding down to the Glivec.

It was only then that I was put on the pill to control the bleeding (I had

never ever been on it before then). At the same time I was put on

transexamic acid to regulate the periods, however all that did was stop the

bleeding completely, rather than control it.

I agree with you that estrogen is now contributing towards the fibroid,

which is now probably the size of a small grapefruit. I have been on the

pill continuously for almost three years, have an appointment at the

hospital in March and will probably need a hysterectomy which I will avoid

if I can. I think it's probably too big now for ablation.

How big are your fibroids? Do they affect your periods? I tell you

something, I REALLY MISS my periods and I never thought I'd say that. I

can't bear the thought of hysterectomy.

And to further add to problems, how will I know when I start going through

menopause otherwise?

I'll be interested to hear from you :-)

Jackie

_____

From: [mailto: ] On Behalf Of Tracey

Sent: Sunday, 11 January 2009 4:33 AM

Subject: Re: [ ] Glivec 800mg

> The side effects are pretty bad though. I had extremely heavy

menstrual bleeding from the start (now on the pill permanently due to

large fibroid, glivec induced),

*******************************************

Hi Jackie,

Sorry to hear about all the side effects you're having. I was

wondering if you could tell me how they determined that your fibroids

were caused by the Gleevec. I've searched a number of medical sites

and wasn't able to find a connection.

I also have fibroids but was told that most women over 35 have them

and the older a woman gets, the more problems the fibroids cause due

to the higher estrogen levels. After menopause when estrogen finally

drops, the fibroids are supposed to cause less problems. Something

to look forward to I guess.

I'd be curious to see any information you have regarding this.

Tracey

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database 3756 (20090110) __________

The message was checked by ESET NOD32 Antivirus.

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Hi Jackie,

I have several small fibroids in varying sizes with the biggest about

3-4 cms. I don't think that they're interfering with my cycle

because I have a fairly normal cycle now.

When I first started on Gleevec though, I had a horrendous time with

heavy bleeding but never had an ultrasound so I really don't know if

there were fibroids that played a role. After about a year my cycle

regulated on its own and became normal. I have no idea why or what

changed.

I was 31 when diagnosed so I don't think age had much to do with it.

I only found out about the fibroids when I was 35 and have no idea

when they started, how long they were there or what, if any effect

they had on things. Keep in mind though that my cycle had already

became regular at this point so I really can't blame the Gleevec for

the fibroids, especially since I was that magical age of 35.

I don't doubt that Gleevec has some effect on our hormones so I guess

it's not far fetched to assume that it could influence fibroid

growth. Since my cycle regulated after a year though, and since my

fibroids are within what would be considered normal for a woman my

age, I can't really conclude that Gleevec caused them.

There are other signs besides lack of menstruation that will tell you

if you are menopausal so don't worry about not knowing.

Tracey

> > The side effects are pretty bad though. I had extremely heavy

> menstrual bleeding from the start (now on the pill permanently due

to

> large fibroid, glivec induced),

>

> *******************************************

>

> Hi Jackie,

>

> Sorry to hear about all the side effects you're having. I was

> wondering if you could tell me how they determined that your

fibroids

> were caused by the Gleevec. I've searched a number of medical sites

> and wasn't able to find a connection.

>

> I also have fibroids but was told that most women over 35 have them

> and the older a woman gets, the more problems the fibroids cause

due

> to the higher estrogen levels. After menopause when estrogen

finally

> drops, the fibroids are supposed to cause less problems. Something

> to look forward to I guess.

>

> I'd be curious to see any information you have regarding this.

>

> Tracey

>

>

>

> __________ Information from ESET NOD32 Antivirus, version of virus

signature

> database 3756 (20090110) __________

>

> The message was checked by ESET NOD32 Antivirus.

>

> http://www.eset.com

>

>

>

>

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Dear Jackie,

Please don't ever feel like you are whining. We are here for the purpose of

helping to heal one another. Being supportive is part of the healing process,

to help you get over the blahs, or whatever else is making your life miserable.

No one else understands, but we do. Collectively, we could write a book about

side effects. There may be someone else out there who is having the same

problem, so go ahead and air it out for all to see and you will feel better

after venting.

Blessings,

Lottie

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Share on other sites

>

> Hi all

>

>

>

> Without whinging and going into details of what is happening to/with

me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you getting?

>

>

>

> I would appreciate all comments regarding side effects.

>

>

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

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Share on other sites

Wow Louis,

I just read your story with tears rolling down my face. Sending you a huge

kiss and hug.

My biggest hurdle now is to get over my big uterus problem. Scary or what. I

was so very glad to receive Sue's message last night.(Sue, you have no idea

what it meant to me reading that from another female).

I am also glad because I do tend to feel very alone with this. 800mg a day

is a hard pill to swallow. I have been so pleased just recently, knowing

that my counts were all good and that I was relatively stable at 0.02%. This

last time there was a blip and it was at 0.05%. I've been feeling depressed

ever since.

I do know that my onc did the right thing in putting me on 800, but even so

....

After reading both your story and Sue's, I feel much closer to you all.

Thank you so much for sharing that with me :-)

Much love and kisses

Jackie

xxxxx

Re: [ ] Glivec 800mg

>

> Hi all

>

>

>

> Without whinging and going into details of what is happening to/with

me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you getting?

>

>

>

> I would appreciate all comments regarding side effects.

>

>

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

Link to comment
Share on other sites

Salu Louis,

Long time no hear or see. It is great to see your post again.

When it comes to our CML stories, we could be twins.

We were both diagnosed in 1999

We both did the Peg Interferon vs Interferon trial.

We both started Gleevec in March 2001

We both saw Dr. Mauro at OHSU.

I beat you in the Zero Club. I'm # 102 and you're # 479.

You beat me in the baby race (1-0 for you, but I keep trying.

Yes, we are truly blessed,

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-282-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

Re: [ ] Glivec 800mg

>

> Hi all

>

>

>

> Without whinging and going into details of what is happening to/with

me, how

> many men and women out there are on the full dose of Glivec 800mg?

How are

> you coping with it? And most importantly what results are you getting?

>

>

>

> I would appreciate all comments regarding side effects.

>

>

>

> Thanks so much,

>

> Jackie

>

>

>

>

>

>

>

> On 800mg since first diagnosis in Nov '04.

>

>

>

>

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Share on other sites

Hello everyone,

Happy New Year to all!!  I guess I am now what was called when I first joined a

CML Board lurker..lol...I use to post, use to chat, but things just got so

hectic and just couldn't find time to post, which is honestly no excuse.  I do

read the posts periodically and noticed the question on 800mg of Gleevec.  I

will share my story. 

I was diagnosed in March 2003.  Before that for a few months I was feeling more

tired then usual, but that was it.  The beginning of the year 2003 I went for my

annual check up and of course the bloodwork came back with my WBC up to 65,000. 

Of course I thought oh I have an infection so just put me on antibidoics. That

didn't work.  Oh yeah, I live in the Cayman Islands so the doctor wanted me to

go to Cleveland Clinic in Florida where he gets some form of " kick back " .  I did

my own research for we had a friend that had Leukeima years back (acute) and he

had a few BMT and lived!!! He went to MD .  For those also with

children, I have twin daughters and at that time they were 12.  My husband and I

thought the best approach was to explain to them as much as we could until we

could find out what was what.  They accompanied us to MD and the

doctors, nurses and everyone there were great.  I think it was a good idea to

let them come

for they were old enough to understand and if god forbid something did happen

they would be able to deal with it a bit better then it being a surprise and

leaving them in the dark.  At the time I went Gleevec was on a trial basis with

the dosages.  I was one of the last lucky ones to be offered the 800mg of

gleevec - 4 in the morning, 4 at night.  Hey remember Zavie the big orange

capsules, now we have little tablets...lol....At the time the doctor stated that

they were seeing better responses in the 600mg-800mg then in the 400mg.  I

didn't have anything to lose so I went on the 800mg.  I was told what the side

effects were, but I honestly never thought they were going to be as bad as they

were.  Living in the Cayman Islands, we also had a horsebackriding business in

which we rode horses on the beach in the sun......here I am being told not to go

in the sun without proper clothing, hats, etc.  Sun lotion may not block the sun

for the side effects

of the medication!!!

I went home just happy to know that Gleevec may be the drug to safe my life and

I could take any type of side effects.  Week number one wasn't so bad, but then

it began.  Name it I had it........water retention, bone pain, the rash, oh my

gosh the rash, that was horrible.  I can't even begin to describe it.  I felt

like I had the flu 24/7.  Sitting in my car running my hand through my hair (I

had hair down to my waist almost), it started coming out!!! This wasn't suppose

to happen but it did!!!  I just kept taking the medication hoping beyond hope

that the side effects would go away.  I probably should have gone off of such a

high dosage, but I was so afraid that if i did i wouldn't get better (not

recommended to everyone).  My bloodwork was being done every week, so exciting

for all my bloodwork was coming back positive.  Felt like you know what, but

otherwise everything was coming back good!!!  I think the side effects lasted

for about 3-6

mths.  One morning I woke up and I started feeling better.  I never gave up and

I think that is the main thing!!!!  It is now going onto 6 years, 6 years I

cannot believe that.  When I was diagnosed all I wanted was to see my daughters

graduate from High School in 2007 AND I DID!!! Now I want to seem them graduate

from college get married and see them happy and hopefully with children!!! LOL

Today they are saying the choice is 600mg, but I am still on 800mg.  Believe it

or not, I tan now, my skin isn't as translucent as it was, water retention, once

in a while.  Being tired well I think we are all tired from time to time.  I

haven't gotten the rash since.  Diarehha, well again depending on what I eat,

some foods do effect it more then others.  Heavy menstrual cycle, if you take

the birth control pill that will control it some what.  I started excercising

last year, lost weight, pretty fit and it does help alot!!!  Try to avoid as

much sugar, keep your carbs down some what and eat plenty of salads/veg/fruit. 

You do feel better with a little bit more energy!!

Sorry for such a lengthy email, but just wanted those to know who have just been

diagnosed that IT DOES GET BETTER!!!

Lottie I see you post alot and I am glad that you are better now!!!!!

Oh my daughters are now 18 and will be going to college this year!!!!  They new

mommy was going to be okay and I think those with children that are of age that

understand let them be a part of it, you don't want them to worry, but it is

good that they understand what is going on!!!

Warm wishes to everyone!!!!

Penny

From: Lottie Duthu <lotajam@...>

Subject: [ ] Re: Glivec 800mg

" CML " < >

Date: Sunday, January 11, 2009, 1:03 AM

Dear Jackie,

Please don't ever feel like you are whining. We are here for the

purpose of helping to heal one another. Being supportive is part of the healing

process, to help you get over the blahs, or whatever else is making your life

miserable. No one else understands, but we do. Collectively, we could write a

book about side effects. There may be someone else out there who is having the

same problem, so go ahead and air it out for all to see and you will feel better

after venting.

Blessings,

Lottie

Link to comment
Share on other sites

What a great email Penny.  Thank you for that.

And you're right about sharing information with my kids. They need to know ahead

of time, so I talked to my two older girls last night.  They were fine and

remained positive for me. They reasurred me that I shouldn't worry ahead of time

about what " might " happen, and I usually keep the same attitude, but I guess

this menstrual cycle got the best of me and my emotions.  I too have fibroids,

and have for about 18 years, but they don't make me bleed more. My previous gyno

told me that I couldn't take the pill because the estrogen would enlarge the

fibroids, but my new young gyno thinks maybe I should take the pill so I'm

confused.

 

________________________________

From: Penny Rivers <pennyhon2003@...>

Sent: Monday, January 12, 2009 5:29:10 AM

Subject: Re: [ ] Re: Glivec 800mg

Hello everyone,

Happy New Year to all!!  I guess I am now what was called when I first joined a

CML Board lurker..lol. ..I use to post, use to chat, but things just got so

hectic and just couldn't find time to post, which is honestly no excuse.  I do

read the posts periodically and noticed the question on 800mg of Gleevec.  I

will share my story. 

I was diagnosed in March 2003.  Before that for a few months I was feeling more

tired then usual, but that was it.  The beginning of the year 2003 I went for my

annual check up and of course the bloodwork came back with my WBC up to 65,000. 

Of course I thought oh I have an infection so just put me on antibidoics. That

didn't work.  Oh yeah, I live in the Cayman Islands so the doctor wanted me to

go to Cleveland Clinic in Florida where he gets some form of " kick back " .  I did

my own research for we had a friend that had Leukeima years back (acute) and he

had a few BMT and lived!!! He went to MD .  For those also with

children, I have twin daughters and at that time they were 12.  My husband and I

thought the best approach was to explain to them as much as we could until we

could find out what was what.  They accompanied us to MD and the

doctors, nurses and everyone there were great.  I think it was a good idea to

let them come

for they were old enough to understand and if god forbid something did happen

they would be able to deal with it a bit better then it being a surprise and

leaving them in the dark.  At the time I went Gleevec was on a trial basis with

the dosages.  I was one of the last lucky ones to be offered the 800mg of

gleevec - 4 in the morning, 4 at night.  Hey remember Zavie the big orange

capsules, now we have little tablets...lol. ...At the time the doctor stated

that they were seeing better responses in the 600mg-800mg then in the 400mg.  I

didn't have anything to lose so I went on the 800mg.  I was told what the side

effects were, but I honestly never thought they were going to be as bad as they

were.  Living in the Cayman Islands, we also had a horsebackriding business in

which we rode horses on the beach in the sun......here I am being told not to go

in the sun without proper clothing, hats, etc.  Sun lotion may not block the sun

for the side effects

of the medication!! !

I went home just happy to know that Gleevec may be the drug to safe my life and

I could take any type of side effects.  Week number one wasn't so bad, but then

it began.  Name it I had it........water retention, bone pain, the rash, oh my

gosh the rash, that was horrible.  I can't even begin to describe it.  I felt

like I had the flu 24/7.  Sitting in my car running my hand through my hair (I

had hair down to my waist almost), it started coming out!!! This wasn't suppose

to happen but it did!!!  I just kept taking the medication hoping beyond hope

that the side effects would go away.  I probably should have gone off of such a

high dosage, but I was so afraid that if i did i wouldn't get better (not

recommended to everyone).  My bloodwork was being done every week, so exciting

for all my bloodwork was coming back positive.  Felt like you know what, but

otherwise everything was coming back good!!!  I think the side effects lasted

for about 3-6

mths.  One morning I woke up and I started feeling better.  I never gave up and

I think that is the main thing!!!!  It is now going onto 6 years, 6 years I

cannot believe that.  When I was diagnosed all I wanted was to see my daughters

graduate from High School in 2007 AND I DID!!! Now I want to seem them graduate

from college get married and see them happy and hopefully with children!!! LOL

Today they are saying the choice is 600mg, but I am still on 800mg.  Believe it

or not, I tan now, my skin isn't as translucent as it was, water retention, once

in a while.  Being tired well I think we are all tired from time to time.  I

haven't gotten the rash since.  Diarehha, well again depending on what I eat,

some foods do effect it more then others.  Heavy menstrual cycle, if you take

the birth control pill that will control it some what.  I started excercising

last year, lost weight, pretty fit and it does help alot!!!  Try to avoid as

much sugar, keep your carbs down some what and eat plenty of salads/veg/fruit. 

You do feel better with a little bit more energy!!

Sorry for such a lengthy email, but just wanted those to know who have just been

diagnosed that IT DOES GET BETTER!!!

Lottie I see you post alot and I am glad that you are better now!!!!!

Oh my daughters are now 18 and will be going to college this year!!!!  They new

mommy was going to be okay and I think those with children that are of age that

understand let them be a part of it, you don't want them to worry, but it is

good that they understand what is going on!!!

Warm wishes to everyone!!!!

Penny

From: Lottie Duthu <lotajamcomcast (DOT) net>

Subject: [ ] Re: Glivec 800mg

" CML " <groups (DOT) com>

Date: Sunday, January 11, 2009, 1:03 AM

Dear Jackie,

Please don't ever feel like you are whining. We are here for the

purpose of helping to heal one another. Being supportive is part of the healing

process, to help you get over the blahs, or whatever else is making your life

miserable. No one else understands, but we do. Collectively, we could write a

book about side effects. There may be someone else out there who is having the

same problem, so go ahead and air it out for all to see and you will feel better

after venting.

Blessings,

Lottie

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Share on other sites

How about the lowest dosage of birth control pills the ones they put younggirls

who suffer from bad cramps

I am glad year girls r supportive. Stay positive there r ssssoooo many

altermatives now

Warm wishes

Penny

Sent from my BlackBerry® wireless device from Cable & Wireless bMobile

[ ] Re: Glivec 800mg

" CML " <groups (DOT) com>

Date: Sunday, January 11, 2009, 1:03 AM

Dear Jackie,

Please don't ever feel like you are whining. We are here for the

purpose of helping to heal one another. Being supportive is part of the healing

process, to help you get over the blahs, or whatever else is making your life

miserable. No one else understands, but we do. Collectively, we could write a

book about side effects. There may be someone else out there who is having the

same problem, so go ahead and air it out for all to see and you will feel better

after venting.

Blessings,

Lottie

Link to comment
Share on other sites

Hi Penny,

Thank you for the update. I miss you on the list and the chats.

You have travelled the journey really well. In the early days CML was a

death sentence. Today it is a chronic disease with side effects that we have

to endure. Tomorrow we look forward to a cure.

Zavie

PS Penny is # 552 in the Zero Club.

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-282-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Penny

Rivers

Sent: January 12, 2009 8:29 AM

Subject: Re: [ ] Re: Glivec 800mg

Hello everyone,

Happy New Year to all!! I guess I am now what was called when I first

joined a CML Board lurker..lol...I use to post, use to chat, but things just

got so hectic and just couldn't find time to post, which is honestly no

excuse. I do read the posts periodically and noticed the question on 800mg

of Gleevec. I will share my story.

I was diagnosed in March 2003. Before that for a few months I was feeling

more tired then usual, but that was it. The beginning of the year 2003 I

went for my annual check up and of course the bloodwork came back with my

WBC up to 65,000. Of course I thought oh I have an infection so just put me

on antibidoics. That didn't work. Oh yeah, I live in the Cayman Islands so

the doctor wanted me to go to Cleveland Clinic in Florida where he gets some

form of " kick back " . I did my own research for we had a friend that had

Leukeima years back (acute) and he had a few BMT and lived!!! He went to MD

. For those also with children, I have twin daughters and at that

time they were 12. My husband and I thought the best approach was to

explain to them as much as we could until we could find out what was what.

They accompanied us to MD and the doctors, nurses and everyone

there were great. I think it was a good idea to let them come

for they were old enough to understand and if god forbid something did

happen they would be able to deal with it a bit better then it being a

surprise and leaving them in the dark. At the time I went Gleevec was on a

trial basis with the dosages. I was one of the last lucky ones to be

offered the 800mg of gleevec - 4 in the morning, 4 at night. Hey remember

Zavie the big orange capsules, now we have little tablets...lol....At the

time the doctor stated that they were seeing better responses in the

600mg-800mg then in the 400mg. I didn't have anything to lose so I went on

the 800mg. I was told what the side effects were, but I honestly never

thought they were going to be as bad as they were. Living in the Cayman

Islands, we also had a horsebackriding business in which we rode horses on

the beach in the sun......here I am being told not to go in the sun without

proper clothing, hats, etc. Sun lotion may not block the sun for the side

effects

of the medication!!!

I went home just happy to know that Gleevec may be the drug to safe my life

and I could take any type of side effects. Week number one wasn't so bad,

but then it began. Name it I had it........water retention, bone pain, the

rash, oh my gosh the rash, that was horrible. I can't even begin to

describe it. I felt like I had the flu 24/7. Sitting in my car running my

hand through my hair (I had hair down to my waist almost), it started coming

out!!! This wasn't suppose to happen but it did!!! I just kept taking the

medication hoping beyond hope that the side effects would go away. I

probably should have gone off of such a high dosage, but I was so afraid

that if i did i wouldn't get better (not recommended to everyone). My

bloodwork was being done every week, so exciting for all my bloodwork was

coming back positive. Felt like you know what, but otherwise everything was

coming back good!!! I think the side effects lasted for about 3-6

mths. One morning I woke up and I started feeling better. I never gave up

and I think that is the main thing!!!! It is now going onto 6 years, 6

years I cannot believe that. When I was diagnosed all I wanted was to see

my daughters graduate from High School in 2007 AND I DID!!! Now I want to

seem them graduate from college get married and see them happy and hopefully

with children!!! LOL

Today they are saying the choice is 600mg, but I am still on 800mg. Believe

it or not, I tan now, my skin isn't as translucent as it was, water

retention, once in a while. Being tired well I think we are all tired from

time to time. I haven't gotten the rash since. Diarehha, well again

depending on what I eat, some foods do effect it more then others. Heavy

menstrual cycle, if you take the birth control pill that will control it

some what. I started excercising last year, lost weight, pretty fit and it

does help alot!!! Try to avoid as much sugar, keep your carbs down some

what and eat plenty of salads/veg/fruit. You do feel better with a little

bit more energy!!

Sorry for such a lengthy email, but just wanted those to know who have just

been diagnosed that IT DOES GET BETTER!!!

Lottie I see you post alot and I am glad that you are better now!!!!!

Oh my daughters are now 18 and will be going to college this year!!!! They

new mommy was going to be okay and I think those with children that are of

age that understand let them be a part of it, you don't want them to worry,

but it is good that they understand what is going on!!!

Warm wishes to everyone!!!!

Penny

From: Lottie Duthu <lotajamcomcast (DOT) <mailto:lotajam%40comcast.net> net>

Subject: [ ] Re: Glivec 800mg

" CML " <groups (DOT) <mailto:%40> com>

Date: Sunday, January 11, 2009, 1:03 AM

Dear Jackie,

Please don't ever feel like you are whining. We are here for the

purpose of helping to heal one another. Being supportive is part of the

healing

process, to help you get over the blahs, or whatever else is making your

life

miserable. No one else understands, but we do. Collectively, we could write

a

book about side effects. There may be someone else out there who is having

the

same problem, so go ahead and air it out for all to see and you will feel

better

after venting.

Blessings,

Lottie

Link to comment
Share on other sites

Hi Zavie,

I miss you also!!! It has just been so hectic these past few months...where do i

begin..lol. We sold our house in October, yeah!!!!!! moved all the horses back

to Florida.  Trying to get the girls in school there so we will probably now be

going back and forth until they graduate.  Remember we have a house there. 

Right now I am back in Cayman with and is in Florida with her

dad.  They couldn't leave the horses for any long period of time, and

have two stallions in which our son can't take care of..so...that is

another storey!!!! LOL

I will defintely try to look for you on the chat this week!!!!

It was great talking to you again!! and yes just yesterday CML was a death

sentence...You are an inspiration to all of us!!! Look at your list on how long

you have had it!!!

Warm wishes

Penny

-- On Mon, 1/12/09, Zavie <zmiller@...> wrote:

From: Zavie <zmiller@...>

Subject: RE: [ ] Re: Glivec 800mg

Date: Monday, January 12, 2009, 4:17 PM

Hi Penny,

Thank you for the update. I miss you on the list and the chats.

You have travelled the journey really well. In the early days CML was a

death sentence. Today it is a chronic disease with side effects that we have

to endure. Tomorrow we look forward to a cure.

Zavie

PS Penny is # 552 in the Zero Club.

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-282-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Penny

Rivers

Sent: January 12, 2009 8:29 AM

Subject: Re: [ ] Re: Glivec 800mg

Hello everyone,

Happy New Year to all!! I guess I am now what was called when I first

joined a CML Board lurker..lol...I use to post, use to chat, but things just

got so hectic and just couldn't find time to post, which is honestly no

excuse. I do read the posts periodically and noticed the question on 800mg

of Gleevec. I will share my story.

I was diagnosed in March 2003. Before that for a few months I was feeling

more tired then usual, but that was it. The beginning of the year 2003 I

went for my annual check up and of course the bloodwork came back with my

WBC up to 65,000. Of course I thought oh I have an infection so just put me

on antibidoics. That didn't work. Oh yeah, I live in the Cayman Islands so

the doctor wanted me to go to Cleveland Clinic in Florida where he gets some

form of " kick back " . I did my own research for we had a friend that

had

Leukeima years back (acute) and he had a few BMT and lived!!! He went to MD

. For those also with children, I have twin daughters and at that

time they were 12. My husband and I thought the best approach was to

explain to them as much as we could until we could find out what was what.

They accompanied us to MD and the doctors, nurses and everyone

there were great. I think it was a good idea to let them come

for they were old enough to understand and if god forbid something did

happen they would be able to deal with it a bit better then it being a

surprise and leaving them in the dark. At the time I went Gleevec was on a

trial basis with the dosages. I was one of the last lucky ones to be

offered the 800mg of gleevec - 4 in the morning, 4 at night. Hey remember

Zavie the big orange capsules, now we have little tablets...lol....At the

time the doctor stated that they were seeing better responses in the

600mg-800mg then in the 400mg. I didn't have anything to lose so I went on

the 800mg. I was told what the side effects were, but I honestly never

thought they were going to be as bad as they were. Living in the Cayman

Islands, we also had a horsebackriding business in which we rode horses on

the beach in the sun......here I am being told not to go in the sun without

proper clothing, hats, etc. Sun lotion may not block the sun for the side

effects

of the medication!!!

I went home just happy to know that Gleevec may be the drug to safe my life

and I could take any type of side effects. Week number one wasn't so bad,

but then it began. Name it I had it........water retention, bone pain, the

rash, oh my gosh the rash, that was horrible. I can't even begin to

describe it. I felt like I had the flu 24/7. Sitting in my car running my

hand through my hair (I had hair down to my waist almost), it started coming

out!!! This wasn't suppose to happen but it did!!! I just kept taking the

medication hoping beyond hope that the side effects would go away. I

probably should have gone off of such a high dosage, but I was so afraid

that if i did i wouldn't get better (not recommended to everyone). My

bloodwork was being done every week, so exciting for all my bloodwork was

coming back positive. Felt like you know what, but otherwise everything was

coming back good!!! I think the side effects lasted for about 3-6

mths. One morning I woke up and I started feeling better. I never gave up

and I think that is the main thing!!!! It is now going onto 6 years, 6

years I cannot believe that. When I was diagnosed all I wanted was to see

my daughters graduate from High School in 2007 AND I DID!!! Now I want to

seem them graduate from college get married and see them happy and hopefully

with children!!! LOL

Today they are saying the choice is 600mg, but I am still on 800mg. Believe

it or not, I tan now, my skin isn't as translucent as it was, water

retention, once in a while. Being tired well I think we are all tired from

time to time. I haven't gotten the rash since. Diarehha, well again

depending on what I eat, some foods do effect it more then others. Heavy

menstrual cycle, if you take the birth control pill that will control it

some what. I started excercising last year, lost weight, pretty fit and it

does help alot!!! Try to avoid as much sugar, keep your carbs down some

what and eat plenty of salads/veg/fruit. You do feel better with a little

bit more energy!!

Sorry for such a lengthy email, but just wanted those to know who have just

been diagnosed that IT DOES GET BETTER!!!

Lottie I see you post alot and I am glad that you are better now!!!!!

Oh my daughters are now 18 and will be going to college this year!!!! They

new mommy was going to be okay and I think those with children that are of

age that understand let them be a part of it, you don't want them to worry,

but it is good that they understand what is going on!!!

Warm wishes to everyone!!!!

Penny

From: Lottie Duthu <lotajamcomcast (DOT) <mailto:lotajam%40comcast.net>

net>

Subject: [ ] Re: Glivec 800mg

" CML " <groups (DOT) <mailto:%40>

com>

Date: Sunday, January 11, 2009, 1:03 AM

Dear Jackie,

Please don't ever feel like you are whining. We are here for the

purpose of helping to heal one another. Being supportive is part of the

healing

process, to help you get over the blahs, or whatever else is making your

life

miserable. No one else understands, but we do. Collectively, we could write

a

book about side effects. There may be someone else out there who is having

the

same problem, so go ahead and air it out for all to see and you will feel

better

after venting.

Blessings,

Lottie

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