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Re: sudden change in pcr results

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Hi Dan,

I would try not to worry about a single test result. Mistakes do

happen and treatment decisions should never be made using a single

test result. With PCR's especially, there's a relatively large

margin of error (up to a half a log) and besides that, you want to

have a couple of tests to see if there is a trend before you can

determine the significance of the results.

The first question that I would ask though is if the lab has changed

their way of testing since your last test. Many labs are now trying

to " get with the program " and do better testing so perhaps this is

the case with your lab. Perhaps they have simply started doing

better (more sensitive) testing.

The other question that you want to know is what the lab's baseline

value is so you can determine how your result compares.

I know it's easier said than done but try not to worry. PCR's do go

up and down.

Take care,

Tracey

>

> I have been in the zero club for several years on 600 mg of

Gleevec.

> Just had a pcr test that had level of 0.5. Should I be worried?

This

> is the first non zero test I have had in years. The doctor is

going to

> repeat the test in 30 days. He did not seem worried, but I am.

>

> Any experience on this sort of thing?

>

> Thanks

>

> Dan

>

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Thanks ,

Its funny...I had gotten so used to Gleevec working perfectly, I had

gotten used to cml and really didn't think much about it. Anyway, I

appreciate your response. Thanks again.

Dan

> >

> > I have been in the zero club for several years on 600 mg of

> Gleevec.

> > Just had a pcr test that had level of 0.5. Should I be worried?

> This

> > is the first non zero test I have had in years. The doctor is

> going to

> > repeat the test in 30 days. He did not seem worried, but I am.

> >

> > Any experience on this sort of thing?

> >

> > Thanks

> >

> > Dan

> >

>

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