time for me to switch from Gleevec to Sprycell

[Guest guest]

Hello All, I know I have gotten out of the posting habit the last many

months, just have had such an overflowing plate. My wife has been away for

months, taking care of her mom who was diagnosed with stage four lung cancer,

so I

have been super wrapped up taking care of so much more around here than

normal.

Well, I am not surprised with the news from my Onc, Gleevec is slowly

loosing its effectivenss with me. I am not sure how I knew, just had that

feeling

inside, I suppose. He never even mentioned he has suspicions, but I know how

I feel and I watched over the last many months my CBC's, I just had a

feeling. Anyhow, I had a BMB a few weeks back, the results were pretty clear,

plus

I am one that has dealt with the side effects of Gleevec. Also, the 30 days

prior to the BMB, we adjusted the Gleevec dosage to 600Mg. I must say, it

reminded me of when I first started Gleevec, it was physical prison.

I had asked this once before, in a different way and more hypothetical than

anything. My Onc said when the Gleevec runs out start Sprycell the next day,

no wash out period. Some on this forum had stated that same protocol a few

months ago. What I am curious, is there any combining of the meds side

effects to be cautious of, should I maybe wait a week in between? I just found

this interesting, I have got to be as careful as possible, staying healthy. I

already know my wife will not be home the last two weeks of Jan, she will be

back at her mom's. Basically that is the plan, she will take the latter two

weeks of each month to stay with her mom, helping her out and making things

as easy as possible for her.

Over all, I am pretty excited to go to a course of action. I am not happy

on Gleevec, how I feel, the fatigue has slowed me so far down and made some of

the heavier task I used to enjoy near impossible. I really hope maybe by

summer to be feeling much better. It is not that I feel horrible, I just do

not feel great and I lack motivation, as I know I now have physical limitations

due to the fatigue and headaches.

I also am a bit nervous to know that I have now worn out the first line of

defense to CML.

Anyhow, thanks for any experiences that you car share.

Regards,

Chris

Dx 01 March 2007

Gleevec 400Mg

Husband to Tabitha

Father to , just turned 15

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