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My son spent nearly the first 6 to 9 months of his life on Augmentin.

new info

In a study released this week, the antibiotic Augmentin TM has been

implicated in the formation of autism. The study published in

Medical Hypotheses strongly suggests the possibility of ammonia

poisoning as a result of young children taking Augmentin.

Distribution Source : PRWeb

Date : Wednesday - January 05, 2005

Yonkers, NY (PRWEB) January 5, 2005 -- In a study released this

week, the antibiotic Augmentin TM has been implicated in the

formation of autism. The study strongly suggests the possibility of

ammonia poisoning as a result of young children taking Augmentin.

Augmentin has been given to children since the late 1980's for

bacterial infections. Composed of amoxicillin and clavulanate

potassium, Augmentin has proven a potent antibacterial, especially

for ear infections which quickly become resistant to amoxicillin

alone.

The manufacture of AugmentinTM involves the fermentation of

clavulanic acid. The fermentation process involves large amounts of

urea/ammonia. Ingested ammonia can potentially injure the intestines

of small children as well as brain and nervous tissue. Even a small

residue of urea/ammonia can potentially induce a substantial brain

inflammation or abnormality.

The study, published in Medical Hypotheses, (2005 64, 312-315)

examines 206 children under the age of 3 diagnosed with autism.

These children were found to have a significantly higher number of

ear infections than the general pediatric population. These same

children received, on average, 12 courses of antibiotics

representing a sum total number of 2480. Of the 2480, 893 of these

courses were Augmentin with 362 of those given under the age of 1

year.

Dr. Joan Fallon, scientist, autism researcher and author of the

study, states that, " Augmentin is one of the most widely prescribed

drugs for children. Its introduction into the marketplace for use in

the treatment of childhood illnesses corresponds with the

significant increase in the incidence of autism. It is possible that

some children, especially those with immaturity, or others at risk

for developmental disorders can be injured by taking this drug. It

is imperative that further research be undertaken to determine if a

subset of children are at risk for neurotoxicity due to the use of

clavulanate or clavulanic acid in pharmaceutical preparations -

especially Augmentin. "

###

Dr. Joan Fallon

914-779-9300

E-mail Information

<http://press.arrivenet.com/hea/article.php/551918.html>

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OMG, my son is on Augmentin RIGHT NOW for double ear infections. He

is 5 1/2 years old & doesn't have any diagnosis as we are currently

doing speech & OT for his Sensory Integration Disorder. The OT

feels if he does have Asperger's, it would be very mild. In any

case, I'm FREAKING right now wondering if this antibiotic may make

him worse!! Does anyone know anymore about this study & if it

affects kids 5+ years old?? Thanks!!! Jackie :)

>

> In a study released this week, the antibiotic Augmentin TM has

been

> implicated in the formation of autism. The study published in

> Medical Hypotheses strongly suggests the possibility of ammonia

> poisoning as a result of young children taking Augmentin.

> Distribution Source : PRWeb

>

> Date : Wednesday - January 05, 2005

>

>

> Yonkers, NY (PRWEB) January 5, 2005 -- In a study released this

> week, the antibiotic Augmentin TM has been implicated in the

> formation of autism. The study strongly suggests the possibility

of

> ammonia poisoning as a result of young children taking Augmentin.

> Augmentin has been given to children since the late 1980's for

> bacterial infections. Composed of amoxicillin and clavulanate

> potassium, Augmentin has proven a potent antibacterial, especially

> for ear infections which quickly become resistant to amoxicillin

> alone.

>

> The manufacture of AugmentinTM involves the fermentation of

> clavulanic acid. The fermentation process involves large amounts

of

> urea/ammonia. Ingested ammonia can potentially injure the

intestines

> of small children as well as brain and nervous tissue. Even a

small

> residue of urea/ammonia can potentially induce a substantial brain

> inflammation or abnormality.

>

> The study, published in Medical Hypotheses, (2005 64, 312–315)

> examines 206 children under the age of 3 diagnosed with autism.

> These children were found to have a significantly higher number of

> ear infections than the general pediatric population. These same

> children received, on average, 12 courses of antibiotics

> representing a sum total number of 2480. Of the 2480, 893 of these

> courses were Augmentin with 362 of those given under the age of 1

> year.

>

> Dr. Joan Fallon, scientist, autism researcher and author of the

> study, states that, " Augmentin is one of the most widely

prescribed

> drugs for children. Its introduction into the marketplace for use

in

> the treatment of childhood illnesses corresponds with the

> significant increase in the incidence of autism. It is possible

that

> some children, especially those with immaturity, or others at risk

> for developmental disorders can be injured by taking this drug. It

> is imperative that further research be undertaken to determine if

a

> subset of children are at risk for neurotoxicity due to the use of

> clavulanate or clavulanic acid in pharmaceutical preparations -

> especially Augmentin. "

>

> ###

>

> Dr. Joan Fallon

> 914-779-9300

> E-mail Information

>

> <http://press.arrivenet.com/hea/article.php/551918.html>

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Here here…

JR spent many months on it to until he was unable to tolerate it …. Gave him

stomach problems big time

-----Original

Message-----

From: Holland Family

[mailto:hollands@...]

Sent: Friday, 14 January 2005 9:24

AM

To:

Autism and Aspergers Treatment

Subject: Re:

new info

My son spent nearly the first

6 to 9 months of his life on Augmentin.

new info

In a study released this week, the antibiotic

Augmentin TM has been

implicated in the formation of autism. The study

published in

Medical Hypotheses strongly suggests the

possibility of ammonia

poisoning as a result of young children taking

Augmentin.

Distribution Source : PRWeb

Date : Wednesday - January 05, 2005

Yonkers, NY (PRWEB) January 5, 2005 -- In a study

released this

week, the antibiotic Augmentin TM has been

implicated in the

formation of autism. The study strongly suggests

the possibility of

ammonia poisoning as a result of young children

taking Augmentin.

Augmentin has been given to children since the

late 1980's for

bacterial infections. Composed of amoxicillin and

clavulanate

potassium, Augmentin has proven a potent

antibacterial, especially

for ear infections which quickly become resistant

to amoxicillin

alone.

The manufacture of AugmentinTM involves the

fermentation of

clavulanic acid. The fermentation process involves

large amounts of

urea/ammonia. Ingested ammonia can potentially

injure the intestines

of small children as well as brain and nervous tissue.

Even a small

residue of urea/ammonia can potentially induce a

substantial brain

inflammation or abnormality.

The study, published in Medical Hypotheses, (2005

64, 312-315)

examines 206 children under the age of 3 diagnosed

with autism.

These children were found to have a significantly

higher number of

ear infections than the general pediatric

population. These same

children received, on average, 12 courses of

antibiotics

representing a sum total number of 2480. Of the

2480, 893 of these

courses were Augmentin with 362 of those given

under the age of 1

year.

Dr. Joan Fallon, scientist, autism researcher and

author of the

study, states that, " Augmentin is one of the

most widely prescribed

drugs for children. Its introduction into the marketplace

for use in

the treatment of childhood illnesses corresponds

with the

significant increase in the incidence of autism.

It is possible that

some children, especially those with immaturity,

or others at risk

for developmental disorders can be injured by

taking this drug. It

is imperative that further research be undertaken

to determine if a

subset of children are at risk for neurotoxicity

due to the use of

clavulanate or clavulanic acid in pharmaceutical

preparations -

especially Augmentin. "

###

Dr. Joan Fallon

914-779-9300

E-mail Information

<http://press.arrivenet.com/hea/article.php/551918.html>

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Jackie,

Honestly, and this is JMO, I wouldn't worry about it. They always have studies saying such and such, and then a little while later, you find out just the opposite. Until something is definite, I wouldn't worry about it too much. As far as autism goes, I think there are all kinds of different things that may trigger autism in certain people with a certain body chemistry. There's no way of knowing right now- maybe some day.

Anne

-- Re: new info

OMG, my son is on Augmentin RIGHT NOW for double ear infections. He is 5 1/2 years old & doesn't have any diagnosis as we are currently doing speech & OT for his Sensory Integration Disorder. The OT feels if he does have Asperger's, it would be very mild. In any case, I'm FREAKING right now wondering if this antibiotic may make him worse!! Does anyone know anymore about this study & if it affects kids 5+ years old?? Thanks!!! Jackie :)> > In a study released this week, the antibiotic Augmentin TM has been > implicated in the formation of autism. The study published in > Medical Hypotheses strongly suggests the possibility of ammonia > poisoning as a result of young children taking Augmentin. > Distribution Source : PRWeb> > Date : Wednesday - January 05, 2005> > > Yonkers, NY (PRWEB) January 5, 2005 -- In a study released this > week, the antibiotic Augmentin TM has been implicated in the > formation of autism. The study strongly suggests the possibility of > ammonia poisoning as a result of young children taking Augmentin. > Augmentin has been given to children since the late 1980's for > bacterial infections. Composed of amoxicillin and clavulanate > potassium, Augmentin has proven a potent antibacterial, especially > for ear infections which quickly become resistant to amoxicillin > alone.> > The manufacture of AugmentinTM involves the fermentation of > clavulanic acid. The fermentation process involves large amounts of > urea/ammonia. Ingested ammonia can potentially injure the intestines > of small children as well as brain and nervous tissue. Even a small > residue of urea/ammonia can potentially induce a substantial brain > inflammation or abnormality.> > The study, published in Medical Hypotheses, (2005 64, 312–315) > examines 206 children under the age of 3 diagnosed with autism. > These children were found to have a significantly higher number of > ear infections than the general pediatric population. These same > children received, on average, 12 courses of antibiotics > representing a sum total number of 2480. Of the 2480, 893 of these > courses were Augmentin with 362 of those given under the age of 1 > year.> > Dr. Joan Fallon, scientist, autism researcher and author of the > study, states that, "Augmentin is one of the most widely prescribed > drugs for children. Its introduction into the marketplace for use in > the treatment of childhood illnesses corresponds with the > significant increase in the incidence of autism. It is possible that > some children, especially those with immaturity, or others at risk > for developmental disorders can be injured by taking this drug. It > is imperative that further research be undertaken to determine if a > subset of children are at risk for neurotoxicity due to the use of > clavulanate or clavulanic acid in pharmaceutical preparations - > especially Augmentin."> > ###> > Dr. Joan Fallon> 914-779-9300> E-mail Information > > <http://press.arrivenet.com/hea/article.php/551918.html>

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OMG, my son is on Augmentin RIGHT NOW for

double ear infections. He

is 5 1/2 years old & doesn't have any

diagnosis as we are currently

doing speech & OT for his Sensory

Integration Disorder. The OT

feels if he does have Asperger's, it would be

very mild. In any

case, I'm FREAKING right now wondering if

this antibiotic may make

him worse!! Does anyone know anymore

about this study & if it

affects kids 5+ years old?? Thanks!!!

Jackie :)

Hi Jackie. Personally I

wouldn’t worry. My son as well had Augmentin, but frankly there were

signs when he was a baby long before the Augmentin prescriptions. He stared at

objects, didn’t smile, point, crawl. He didn’t sleep,,,etc. I

wouldn’t worry, Gail

..

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I saw the study and wondered about it myself. I do know there are meds that aggravate their behavior. Augmentin is really hard on the GI system.

MISSYSAHM to some special kids!!!

I am who I am because that's who I am--, 5, Aspergers

All kids are gifted; some just open theirpackages earlier than others.

-- Carr

Re: new info

OMG, my son is on Augmentin RIGHT NOW for double ear infections. He is 5 1/2 years old & doesn't have any diagnosis as we are currently doing speech & OT for his Sensory Integration Disorder. The OT feels if he does have Asperger's, it would be very mild. In any case, I'm FREAKING right now wondering if this antibiotic may make him worse!! Does anyone know anymore about this study & if it affects kids 5+ years old?? Thanks!!! Jackie :)> > In a study released this week, the antibiotic Augmentin TM has been > implicated in the formation of autism. The study published in > Medical Hypotheses strongly suggests the possibility of ammonia > poisoning as a result of young children taking Augmentin. > Distribution Source : PRWeb> > Date : Wednesday - January 05, 2005> > > Yonkers, NY (PRWEB) January 5, 2005 -- In a study released this > week, the antibiotic Augmentin TM has been implicated in the > formation of autism. The study strongly suggests the possibility of > ammonia poisoning as a result of young children taking Augmentin. > Augmentin has been given to children since the late 1980's for > bacterial infections. Composed of amoxicillin and clavulanate > potassium, Augmentin has proven a potent antibacterial, especially > for ear infections which quickly become resistant to amoxicillin > alone.> > The manufacture of AugmentinTM involves the fermentation of > clavulanic acid. The fermentation process involves large amounts of > urea/ammonia. Ingested ammonia can potentially injure the intestines > of small children as well as brain and nervous tissue. Even a small > residue of urea/ammonia can potentially induce a substantial brain > inflammation or abnormality.> > The study, published in Medical Hypotheses, (2005 64, 312–315) > examines 206 children under the age of 3 diagnosed with autism. > These children were found to have a significantly higher number of > ear infections than the general pediatric population. These same > children received, on average, 12 courses of antibiotics > representing a sum total number of 2480. Of the 2480, 893 of these > courses were Augmentin with 362 of those given under the age of 1 > year.> > Dr. Joan Fallon, scientist, autism researcher and author of the > study, states that, "Augmentin is one of the most widely prescribed > drugs for children. Its introduction into the marketplace for use in > the treatment of childhood illnesses corresponds with the > significant increase in the incidence of autism. It is possible that > some children, especially those with immaturity, or others at risk > for developmental disorders can be injured by taking this drug. It > is imperative that further research be undertaken to determine if a > subset of children are at risk for neurotoxicity due to the use of > clavulanate or clavulanic acid in pharmaceutical preparations - > especially Augmentin."> > ###> > Dr. Joan Fallon> 914-779-9300> E-mail Information > > <http://press.arrivenet.com/hea/article.php/551918.html>

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  • 2 years later...
Guest guest

Hi, I'm Tracey and a Pharmacist. I am so sorry for what is happening to you. I am concerned that my fellow diversion participant who tested + a week ago Friday has also been suspended because this is her third + in a year. I haven't been able to get ahold of her. I am frustrated, trying to get an attorney who can comprehend the complicated situation we are all in. What state do you practice in? Take care and hold on! doetta5555 <doetta5555@...> wrote: I just received a call from my probation monitor that I have been suspended from working as a nurse because of my positive tests. Your input and support would be gratefully appreciated, Diane

Pinpoint customers who are looking for what you sell.

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Guest guest

So sorry this happened to you. Sorry you have joined the ranks with

us who have been suspended from working. Our club is an awful one.

I was suspended for 2 weeks back in October after a fouth positive

etg in 2 years, the 3rd positive in 6 months! The harder I tried,

the higher my levels were coming back. I was at such a loss.

Thankfully, I was already scheduled to meet with my diversion

committee at the end of the 2nd week, and after they spoke to me and

reviewed my records and I had 3 negative urines in a row I was

allowed to return to work. I was told they did not feel I had

relapsed, but if I have one more positive I would have to start the

program over, and possibly go to treatment. Considering I had no

idea what was causing the positives, this was a terrible threat for

me, and I lost a lot of weight, developed migraines (thankfully they

have passed), but have not had another positive urine (yet). The

only thing that has been different is that I stopped the b.i.d.

Ditropan and advil I was taking. I also don't order anything that

might have marinated meat in it, and take my own dressing to

restaurants (catalina seems to be okay-for me). I truly believe

there is something about the meds we are on, and I hope you are on

something and can change it to a med that is excreted through the

renal system, as that would be the best solution for a very

problematic situation.

Please remember you are among friends. My solution when I was

removed from work was that I stayed consistent with my schedule (gym,

meetings), and hung out with my friends who are retired now and had

time to go to movies and other outings. I also attended a nursing

conference in Las Vegas that I had been scheduled to attend. I just

didn't get to use training hours from work, I had to use my paid time

off, but I think it was a very healthy thing to do, and I kept my

schedule consistent in Vegas as well.

Good luck and stay in touch,

Robin

--- doetta5555 <doetta5555@...> wrote:

> I just received a call from my probation monitor that I have been

> suspended from working as a nurse because of my positive tests.

> Your

> input and support would be gratefully appreciated, Diane

>

>

________________________________________________________________________________\

____

The fish are biting.

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Guest guest

very sick of them and sad for you and us diane...can you share specifics numbers with creatinine values if you have them,exposure sources pills supplements of any kind DOC any concurrent medical conditions?hang in there,regards,r doetta5555 <doetta5555@...> wrote: I just received a call from my probation monitor that I have been suspended from working as a nurse because of my positive tests. Your input and support would be gratefully appreciated,

Diane

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Guest guest

I am in Woodland, near , CA. I was told the #'s of the etg's,

between 500-900. then the last one was 1800!!! But was never given any

creatinine levels. Who would I call for that? Compass Vision? I am on

trazadone, wellbutrin, effexor, atenolol, hctz, nifedical XL,

tinazadine, asa, was on tylenol and nsaids but I stopped those. Was on

pain meds after my automobile accident but I've finished with those. I

take a prenatal vitamin. I have slightly elevated alt, my cholesterol

and triglycerides are high and I am prediabetic. My glomerular

filtration rate is decreased, that's why the Dr. said no more nsaids

ever again in my life! I was trying to look up the SAMSHA article

yesterday and it says error, unable to find.

I wasn't told yet when I can return for work. I received something from

the AG's office and may have to go to a hearing. I haven't had to do

that yet. I was in diversion from 1995-2002, then was kicked out because

I had too many relapses on pain meds. I have been on probation for 1 yr.

Hindsight is 20/20 but I'm not going there. Today I have a year clean

and sober!!! Thanks for all your help and advice, Diane

I just received a call

from my probation monitor that I have been

> suspended from working as a nurse because of my positive tests. Your

> input and support would be gratefully appreciated, Diane

>

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Guest guest

Hi Diane,

Your probation monitor would have the creatinines. They're on the lab report.

Here's a link to the SAMHSA advisory: http://www.kap.samhsa.gov/products/manuals/advisory/pdfs/0609_biomarkers.pdf

If you have a AG hearing, I would love to attend, if that is allowed. I can only tell you that the deputy AG who handled my case assured me that I would NOT lose my license d/t EtG. In other words, low-level EtG results WILL NOT HOLD UP in the administrative courts here in CA (and that is thanks to the SAMHSA advisory, for the most part).

Lorie.

Re: New info

I am in Woodland, near , CA. I was told the #'s of the etg's, between 500-900. then the last one was 1800!!! But was never given any creatinine levels. Who would I call for that? Compass Vision? I am on trazadone, wellbutrin, effexor, atenolol, hctz, nifedical XL, tinazadine, asa, was on tylenol and nsaids but I stopped those. Was on pain meds after my automobile accident but I've finished with those. I take a prenatal vitamin. I have slightly elevated alt, my cholesterol and triglycerides are high and I am prediabetic. My glomerular filtration rate is decreased, that's why the Dr. said no more nsaids ever again in my life! I was trying to look up the SAMSHA article yesterday and it says error, unable to find.I wasn't told yet when I can return for work. I received something from the AG's office and may have to go to a hearing. I haven't had to do that yet. I was in diversion from 1995-2002, then was kicked out because I had too many relapses on pain meds. I have been on probation for 1 yr. Hindsight is 20/20 but I'm not going there. Today I have a year clean and sober!!! Thanks for all your help and advice, Diane I just received a call from my probation monitor that I have been > suspended from working as a nurse because of my positive tests. Your > input and support would be gratefully appreciated, Diane>

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trazadone,welbutrin,effexor all liver drugs......discuss with treating md taper as much as possible of all liver drugs and/or take so you test outside of the half life of the drugs should help...congrats on your recovery,hang in there,rdoetta5555 <doetta5555@...> wrote: I am in Woodland, near , CA. I was told the #'s of the etg's, between 500-900. then the last one was 1800!!! But was never given any creatinine levels. Who would I call for that? Compass Vision? I am on trazadone, wellbutrin,

effexor, atenolol, hctz, nifedical XL, tinazadine, asa, was on tylenol and nsaids but I stopped those. Was on pain meds after my automobile accident but I've finished with those. I take a prenatal vitamin. I have slightly elevated alt, my cholesterol and triglycerides are high and I am prediabetic. My glomerular filtration rate is decreased, that's why the Dr. said no more nsaids ever again in my life! I was trying to look up the SAMSHA article yesterday and it says error, unable to find.I wasn't told yet when I can return for work. I received something from the AG's office and may have to go to a hearing. I haven't had to do that yet. I was in diversion from 1995-2002, then was kicked out because I had too many relapses on pain meds. I have been on probation for 1 yr. Hindsight is 20/20 but I'm not going there. Today I have a year clean and sober!!! Thanks for all your help and advice, Diane I just received a call from my probation monitor that I have been > suspended from working as a nurse because of my positive tests. Your > input and support would be gratefully appreciated, Diane>

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Guest guest

Thanks so much Lorie. I know you are the etg expert. Hey, can my

lawyer call you if needed? He's in Sacramento but he's not the one

you mentioned. Mine is Ron Kaldor. Later, Diane I just received a call

> from my probation monitor that I have been

> > suspended from working as a nurse because of my positive tests.

Your

> > input and support would be gratefully appreciated, Diane

> >

>

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Guest guest

Thanks so much Lorie. I know you are the etg expert. Hey, can my

lawyer call you if needed? He's in Sacramento but he's not the one

you mentioned. Mine is Ron Kaldor. Later, Diane I just received a call

> from my probation monitor that I have been

> > suspended from working as a nurse because of my positive tests.

Your

> > input and support would be gratefully appreciated, Diane

> >

>

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Guest guest

Thanks Robin. I don't know if I can taper off my antidepressants. I

will talk to my Dr. about it. He doesn't know anything about etg,

only what I've told him. Diane I just received a call

> from my probation monitor that I have been

> > suspended from working as a nurse because of my positive tests.

Your

> > input and support would be gratefully appreciated, Diane

> >

>

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Guest guest

I'm not an EtG expert. Dr. Skipper is the EtG guru...but what ever happened to him?

In reality, 3+ years after EtG's introduction to the marketplace, there really are no EtG experts. There's lots of speculation about the "science of EtG" but few new hard facts. That is really sad.

I'd be happy to talk to Mr. Kaldor about what seemed to help in my own case.

Lorie

Re: New info

Thanks so much Lorie. I know you are the etg expert. Hey, can my lawyer call you if needed? He's in Sacramento but he's not the one you mentioned. Mine is Ron Kaldor. Later, Diane I just received a call > from my probation monitor that I have been > > suspended from working as a nurse because of my positive tests. Your > > input and support would be gratefully appreciated, Diane> >>

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  • 1 year later...

melva

i have to have surgery on the 27 of this month for a c-toma and my ear itchs really bad and burns and i have alot of pressure and it hurts to touch behind my ear cause it is very sore the dr said mine was in my middle ear.not sure what yours is..

SANDY SMALL

From: Melva <dbuck5@...>Subject: new infocholesteatoma Date: Saturday, January 17, 2009, 2:13 PM

I had an audiologist look over my papers and I have an external ear canal cholesteatoma. We are assuming it was the lesion that was removed by biopsy. The pneumonia that I had over Christmas caused an ear infection and stirred up the problem again. My Dr said that I will need periodic cleaning. He suggested 6 months but I made the appt for 3 months. I have pressure in my sinus area and the side under that ear is very sore. The ear feels itchy. The Dr said it was rare and he felt confident to not do a CT because my ear drum is intact. I am having to feel the discomfort and trust this Dr. Does anyone on this list have the ear canal kind?------------------------------------

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  • 3 weeks later...

Hello All,

Just found this bit of info & thought it may be of some

interest, I know it mentions " Acute " but this may be relevant to CML:

Cell find 'lifts leukaemia fight'

Purple acute myelod leukaemia cells visible amongst the blood cells

Research which sheds light on how blood cancer cells work may improve

the power of leukaemia treatments.

A Stanford University study found that leukaemia " stem cells " , which

drive the spread of the cancer, work differently to healthy blood

stem cells.

This might mean they could be targeted and destroyed more easily.

The study, published in the journal Cell Stem Cell, might one day

reduce the chances of leukaemia returning after treatment, say

experts.

These findings may have a substantial clinical impact

Dr Tim Somervaille

Study author

Cancer was once regarded a disease in which all malignant cells were

the same, but in recent years, cancer researchers have focused on the

role of cancer " stem cells " .

These, like healthy stem cells, provide a source for new cells, and

it is important to kill these to stop the cancer regrouping and

returning.

This is a problem in leukaemia, in which there can be a significant

risk of relapse even after apparently successful chemotherapy.

Conventional treatment for some forms of leukaemia destroys both

leukaemia cells and healthy blood cells, but the latest research may

point to ways in which therapies can be fine tuned to pick off the

leukaemia stem cells more efficiently.

The researchers found difference between two types of stem cells.

Leukaemia stem cells, they found, tap into a genetic mechanism

normally harnessed by stem cells in the embryo to allow their

division into fresh cells.

Normal blood stem cells use a difference mechanism to prompt their

growth.

This means that, in theory at least, drugs which targeted this

process would stop leukaemia stem cells dividing, while leaving

healthy blood stem cells unharmed.

Root removal

Dr Tim Somervaille, who led the research, said: " This study

highlights the great potential of treatment aimed at genes and

pathways that are of great importance to the function of leukaemia

stem cells.

" These findings may have a substantial clinical impact. "

A spokesman from charity Leukaemia Research, said the research could

also help make future treatments better at completely wiping out

leukaemia stem cells.

He said: " We will only be able to cure leukaemia if we can target and

kill the leukaemia stem cells, something that current chemotherapy

may not be doing as we would like.

" If you killed 90% of the leukaemia cells, but only 10% of these

leukaemia stem cells, you haven't done well enough.

" This approach is like ripping out the roots of the cancer as well as

the growth above the surface. "

He said he would expect any treatment arising from the research to be

delivered in combination with other anti-cancer drugs.

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